papaverine has been researched along with Cochlear Hearing Loss in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine hydrochloride is a direct-acting vasodilator used to manage vasospasm during various neurosurgical operations." | 1.35 | Adverse effects of topical papaverine on auditory nerve function. ( Asher, AL; Chadwick, GM; Pollard, RJ; Van Der Veer, CA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chadwick, GM | 1 |
| Asher, AL | 1 |
| Van Der Veer, CA | 1 |
| Pollard, RJ | 1 |
| Byl, FM | 1 |
| Umemura, K | 1 |
| Takiguchi, Y | 1 |
| Nakashima, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss[NCT05112354] | Phase 2 | 40 participants (Actual) | Interventional | 2019-12-01 | Completed | ||
| Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.[NCT02204618] | 160 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Cochlear Hearing Loss
| Article | Year |
|---|---|
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
2 other studies available for papaverine and Cochlear Hearing Loss
| Article | Year |
|---|---|
Adverse effects of topical papaverine on auditory nerve function.
Topics: Administration, Topical; Afferent Pathways; Aged; Aged, 80 and over; Basilar Artery; Cochlear Nerve; | 2008 |
Altered effect of arachidonic acid on inner ear blood flow in rats with streptozotocin-induced diabetes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Audiometry, Evoked Response; Diabetes Mellitus, Experi | 1991 |