papaverine has been researched along with Cirrhosis in 17 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracorporeal papaverine self-injection is a new therapy for erectile dysfunction." | 7.67 | Papaverine-induced fibrosis of the corpus cavernosum. ( Brawer, MK; Fuchs, ME, 1989) |
| "Intracavernous administration of papaverine and phentolamine has become an essential and indispensible element in the diagnosis and treatment of erectile dysfunction." | 4.77 | How safe is the treatment of impotence with intracavernous autoinjection? ( Ludwig, G; Zentgraf, M; Ziegler, M, 1989) |
| "Using papaverine, papaverine/phentolamine, or prostaglandin E1 (PGE1), intracavernosal pharmacotherapy has been successful in treating erectile dysfunction." | 3.69 | Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction. ( Chao, R; Clowers, DE, 1994) |
| "We report 3 cases of penile curvature deformity and fibrosis of the tunica albuginea after long-term self-injection with papaverine hydrochloride and phentolamine mesylate." | 3.67 | Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection. ( Burks, C; Christy, WC; Hu, KN, 1987) |
| "Intracorporeal papaverine self-injection is a new therapy for erectile dysfunction." | 3.67 | Papaverine-induced fibrosis of the corpus cavernosum. ( Brawer, MK; Fuchs, ME, 1989) |
| " Dose-dependent response with reversed drug sensitivity was found in the papaverine group, but only elongation to tumescence was found in the PGE1 group, even with double dosage (probably because of scarce PGE1 receptors in monkey's penile tissue)." | 1.28 | Histopathological change of corpora cavernosa after long-term intracavernous injection. ( Chu, HW; Ho, WL; Hwang, TI; Yang, CR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asuar Aydillo, S | 1 |
| Moemen, MN | 1 |
| Hamed, HA | 1 |
| Kamel, II | 1 |
| Shamloul, RM | 1 |
| Ghanem, HM | 1 |
| Meinhardt, W | 1 |
| Lycklama à Nijeholt, AA | 1 |
| Kropman, RF | 1 |
| Vermeij, P | 1 |
| Zwartendijk, J | 1 |
| Chao, R | 1 |
| Clowers, DE | 1 |
| De Rose, AF | 1 |
| Oppezzi, GF | 1 |
| Scotto, S | 1 |
| Casabé, A | 1 |
| Bechara, A | 1 |
| Cheliz, G | 1 |
| Romano, S | 1 |
| Rey, H | 1 |
| Fredotovich, N | 1 |
| Sahin, M | 1 |
| Başar, MM | 1 |
| Bozdoğan, O | 1 |
| Atan, A | 1 |
| Hwang, TI | 1 |
| Yang, CR | 1 |
| Ho, WL | 1 |
| Chu, HW | 1 |
| Stief, CG | 2 |
| Wetterauer, U | 1 |
| Kulvelis, F | 1 |
| Popken, G | 1 |
| Staubesand, J | 1 |
| Sommerkamp, H | 1 |
| Lakin, MM | 1 |
| Montague, DK | 1 |
| VanderBrug Medendorp, S | 1 |
| Tesar, L | 1 |
| Schover, LR | 1 |
| Gall, H | 1 |
| Scherb, W | 1 |
| Bähren, W | 1 |
| Hu, KN | 1 |
| Burks, C | 1 |
| Christy, WC | 1 |
| Zentgraf, M | 1 |
| Ludwig, G | 1 |
| Ziegler, M | 1 |
| Fuchs, ME | 1 |
| Brawer, MK | 1 |
| Corriere, JN | 1 |
| Fishman, IJ | 1 |
| Benson, GS | 1 |
| Carlton, CE | 1 |
| Abozeid, M | 1 |
| Juenemann, KP | 1 |
| Luo, JA | 1 |
| Lue, TF | 1 |
| Yen, TS | 1 |
| Tanagho, EA | 1 |
| Larsen, EH | 1 |
| Gasser, TC | 1 |
| Bruskewitz, RC | 1 |
1 review available for papaverine and Cirrhosis
| Article | Year |
|---|---|
How safe is the treatment of impotence with intracavernous autoinjection?
Topics: Drug Combinations; Erectile Dysfunction; Fibrosis; Humans; Male; Papaverine; Penile Erection; Penis; | 1989 |
2 trials available for papaverine and Cirrhosis
| Article | Year |
|---|---|
Clinical and sonographic assessment of the side effects of intracavernous injection of vasoactive substances.
Topics: Adult; Alprostadil; Drug Combinations; Erectile Dysfunction; Fibrosis; Humans; Injections, Intralesi | 2004 |
Comparison of a mixture of papaverine, phentolamine and prostaglandin E1 with other intracavernous injections.
Topics: Alprostadil; Drug Combinations; Erectile Dysfunction; Fibrosis; Follow-Up Studies; Humans; Injection | 1994 |
14 other studies available for papaverine and Cirrhosis
| Article | Year |
|---|---|
[Current role of intracavernous therapy in the treatment of erectile dysfunction].
Topics: Adrenergic alpha-Antagonists; Alprostadil; Clinical Trials as Topic; Drug Combinations; Erectile Dys | 2002 |
Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction.
Topics: Adult; Alprostadil; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Drug Monitoring; Drug Syne | 1994 |
[Local complications of papaverine-induced erection: follow-up at 7 years].
Topics: Adult; Aged; Erectile Dysfunction; Fibrosis; Follow-Up Studies; Humans; Hypertrophy; Male; Middle Ag | 1993 |
Drop-out reasons and complications in self-injection therapy with a triple vasoactive drug mixture in sexual erectile dysfunction.
Topics: Adult; Aged; Alprostadil; Erectile Dysfunction; Fibrosis; Humans; Male; Middle Aged; Papaverine; Pen | 1998 |
Short-term histopathologic effects of different intracavernosal agents on corpus cavernosum and antifibrotic activity of intracavernosal verapamil: an experimental study.
Topics: Alprostadil; Animals; Calcium Channel Blockers; Chemical and Drug Induced Liver Injury; Disease Mode | 2001 |
Histopathological change of corpora cavernosa after long-term intracavernous injection.
Topics: Alprostadil; Animals; Dose-Response Relationship, Drug; Erectile Dysfunction; Fibrosis; Injections; | 1991 |
Intracavernous drug delivery system: an alternative to intracavernous injection in the treatment of impotence?
Topics: Animals; Drug Combinations; Erectile Dysfunction; Fibrosis; Infusion Pumps, Implantable; Macaca fasc | 1990 |
Intracavernous injection therapy: analysis of results and complications.
Topics: Drug Therapy, Combination; Erectile Dysfunction; Fibrosis; Hematoma; Humans; Male; Middle Aged; Papa | 1990 |
Erectile response to intracavernous injection of vasoactive drugs after penile prosthesis removal.
Topics: Aged; Fibrosis; Humans; Injections; Male; Middle Aged; Papaverine; Penile Erection; Penile Prosthesi | 1990 |
Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection.
Topics: Aged; Drug Combinations; Erectile Dysfunction; Fibrosis; Humans; Male; Middle Aged; Papaverine; Peni | 1987 |
Papaverine-induced fibrosis of the corpus cavernosum.
Topics: Erectile Dysfunction; Fibrosis; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penis; Self | 1989 |
Development of fibrotic penile lesions secondary to the intracorporeal injection of vasoactive agents.
Topics: Adult; Erectile Dysfunction; Fibrosis; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penis | 1988 |
Chronic papaverine treatment: the effect of repeated injections on the simian erectile response and penile tissue.
Topics: Animals; Dose-Response Relationship, Drug; Fibrosis; Hypertrophy; Injections; Liver; Macaca fascicul | 1987 |
Fibrosis of corpus cavernosum after intracavernous injection of phentolamine/papaverine.
Topics: Adult; Drug Combinations; Erectile Dysfunction; Fibrosis; Humans; Injections; Male; Papaverine; Peni | 1987 |