papaverine has been researched along with Cholestasis in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isales, CM | 1 |
| Nathanson, MH | 1 |
| Bruck, R | 1 |
| Lenzen, R | 2 |
| Funk, A | 1 |
| Kolb-Bachofen, V | 1 |
| Strohmeyer, G | 1 |
| Akerboom, T | 1 |
| Schneider, I | 1 |
| Sies, H | 1 |
| Wolloch, Y | 1 |
| Dintsman, M | 1 |
4 other studies available for papaverine and Cholestasis
| Article | Year |
|---|---|
Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure.
Topics: Animals; Bile; Blood Pressure; Calcium; Cholestasis; Endothelins; Male; Papaverine; Portal System; R | 1993 |
Norepinephrine-induced cholestasis in the isolated perfused rat liver is secondary to its hemodynamic effects.
Topics: Animals; Bile; Cholestasis; Hemodynamics; In Vitro Techniques; Liver; Male; Norepinephrine; Papaveri | 1990 |
Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Bile; Blood Pressure; Calcimycin; Cholestasis; Liver; Male; Microci | 1987 |
Carcinoma of the large intestine in children.
Topics: Adenocarcinoma; Adolescent; Atropa belladonna; Child; Cholestasis; Colonic Neoplasms; Female; Follow | 1974 |