papaverine has been researched along with Central Nervous System Origin Vertigo in 10 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the first double-blind study in outpatients to evaluate the effectiveness of dihydrogenated ergot alkaloids (DEA) (Hydergine) versus papaverine in the treatment of selected symptoms associated with mental aging." | 5.04 | Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine). ( Rosen, HJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOHMANN, H | 2 |
| STOLL, HG | 1 |
| Byl, FM | 1 |
| Rosen, HJ | 1 |
| Feine-Haake, G | 1 |
| Neiss, A | 1 |
| Weinert, W | 1 |
| Agnoli, A | 2 |
| Piccinelli, A | 1 |
| Neri, G | 1 |
| Turner, JS | 1 |
| Saunders, AZ | 1 |
| Per-Lee, JH | 1 |
| Straube, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss[NCT05112354] | Phase 2 | 40 participants (Actual) | Interventional | 2019-12-01 | Completed | ||
| Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.[NCT02204618] | 160 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Central Nervous System Origin Vertigo
| Article | Year |
|---|---|
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
3 trials available for papaverine and Central Nervous System Origin Vertigo
| Article | Year |
|---|---|
Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine).
Topics: Aged; Aging; Clinical Trials as Topic; Confusion; Dementia; Depression; Dihydroergotoxine; Ergoloid | 1975 |
[The treatment of cerebrovascular insufficiency. Their evaluation in a double-blind study].
Topics: Aged; Aging; Cerebrovascular Disorders; Clinical Trials as Topic; Confusion; Drug Combinations; Drug | 1975 |
[Long-term medical treatment of acute cerebrovascular disease sequelae (comparison papaverine-piribedil].
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Dioxoles; Drug Eva | 1974 |
6 other studies available for papaverine and Central Nervous System Origin Vertigo
| Article | Year |
|---|---|
[Contribution to the management of labyrinthine and vasomotor vertigo].
Topics: Humans; Meniere Disease; Papaverine; Quinine; Vertigo | 1956 |
[Further experiences with the treatment of labyrinthine & vasomotor dizziness; contribution to the problem of placebos].
Topics: Dizziness; Humans; Meniere Disease; Papaverine; Quinine; Vertigo | 1958 |
[On the medicinal treatment of dizziness].
Topics: Dizziness; Humans; Meniere Disease; Papaverine; Quinine; Vertigo | 1960 |
[Problems in the long-term medical treatment of sequelae of acute cerebrovascular diseases. Double-blind studies].
Topics: Cerebrovascular Disorders; Cognition Disorders; Emotions; Headache; Humans; Mental Processes; Motor | 1976 |
A 10-year profile of Meniere's disease and endolymphatic shunt surgery.
Topics: Adult; Aged; Ear, Inner; Female; Hearing; Histamine; Humans; Labyrinthine Fluids; Male; Meniere Dise | 1973 |
[On the evaluation and treatment of vertigo in the neurological practice].
Topics: Humans; Papaverine; Quinine; Vertigo | 1969 |