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papaverine and Cavernitis, Fibrous

papaverine has been researched along with Cavernitis, Fibrous in 32 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"Priapism was not encountered during self-injection but it did occur twice in 329 physician-administered injections."5.28Side effects of self-administration of intracavernous papaverine and phentolamine for the treatment of impotence. ( Althof, SE; Bodner, DR; Kursh, ED; Levine, SB; Resnick, MI; Risen, CB; Turner, LA, 1989)
"Fourteen patients with organic impotence received intracorporeal injections of papaverine and were then monitored by Rigiscan."5.27Utility of Rigiscan and papaverine in diagnosis of erectile impotence. ( Badlani, GH; Weinberg, JJ, 1988)
"From May 1985 to July 1989, 143 patients suffering from chronic erectile dysfunction (21-70 years old) underwent constant corpus cavernosum auto-injection therapy (CCAT) with papaverine alone (1257 injections) or with a standardized papaverine-phentolamine mixture (11035 injections)."3.68[Long-term results of corpus cavernosum auto-injection therapy in treatment of patients with chronic erectile dysfunction]. ( Bähren, W; Gall, H; Holzki, G; Irion, R; Scherb, W; Sparwasser, C, 1992)
"Penile indurations were found at follow-up examination in six of 120 patients with erectile dysfunction who practice intracavernosal self-injection of papaverine-phentolamine."3.68Intracorporeal calcifications after self-injection of papaverine. ( Kaftori, JK; Pery, M; Rosenberger, A; Vardi, Y, 1990)
"In erectile dysfunction formerly, for both diagnostic and therapeutic purposes, intracavernous injections of papaverine and the combination papaverine/phentolamine were employed."3.68[Prostaglandin E1 injection in erectile dysfunction. Current diagnostic and therapeutic possibilities]. ( Schrey, A, 1990)
"We report 3 cases of penile curvature deformity and fibrosis of the tunica albuginea after long-term self-injection with papaverine hydrochloride and phentolamine mesylate."3.67Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection. ( Burks, C; Christy, WC; Hu, KN, 1987)
"A total of 78 patients 17 to 84 years old reported their experience via questionnaire with the papaverine-phentolamine injection technique for impotence."3.67Intracavernous self-injection for impotence: a long-term therapeutic option? Experience in 78 patients. ( Bruskewitz, RC; Feyzi, J; Gasser, TC; Girdley, FM; Graversen, PH, 1988)
"Results from 31 men with vasculogenic impotence were compared with those from 17 men with non-vasculogenic impotence and a control group of 6 potent men."1.28The role of colour duplex ultrasonography in the diagnosis of vasculogenic impotence. ( Oates, CP; Pickard, RS; Powell, PH; Sethia, KK, 1991)
" A further advantage of the method is the lower dosage required, which means that the gonads are exposed to less radiation."1.28[Cavernosography using digital luminescence radiography (DLR) in the diagnosis of venous induced erectile function and of diseases of the corpus cavernosum]. ( Christiansen, GR; Marks, W; Papadopoulos, I; Weichert-Jacobsen, K, 1991)
"The remaining 132 patients had erectile impotence of various etiologies."1.28Evaluation of vasculogenic erectile impotence using penile duplex ultrasonography. ( Dunn, JK; Fishman, IJ; Quesada, ET; Seale-Hawkins, CK; Shabsigh, R, 1989)
"Priapism was not encountered during self-injection but it did occur twice in 329 physician-administered injections."1.28Side effects of self-administration of intracavernous papaverine and phentolamine for the treatment of impotence. ( Althof, SE; Bodner, DR; Kursh, ED; Levine, SB; Resnick, MI; Risen, CB; Turner, LA, 1989)
"Fourteen patients with organic impotence received intracorporeal injections of papaverine and were then monitored by Rigiscan."1.27Utility of Rigiscan and papaverine in diagnosis of erectile impotence. ( Badlani, GH; Weinberg, JJ, 1988)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.00)18.7374
1990's16 (50.00)18.2507
2000's5 (15.63)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ismail, A1
Tabari, AM1
Alhasan, SU1
Abdullahi, A1
Goldstein, I1
Levine, LA2
Goldman, KE1
Greenfield, JM1
Monga, M1
Cosgrove, D1
Zupkas, P1
Jain, A1
Kasyan, A1
Wilkes, N1
Rajasekaran, M1
Kadioglu, A1
Oktar, T1
Kandirali, E1
Kendirci, M1
Sanli, O1
Ozsoy, C1
Shioshvili, TJ1
Kakonashvili, AP1
Ohebshalom, M1
Mulhall, JP1
Porst, H1
Buvat, J1
Buvat-Herbaut, M1
Lemaire, A1
Marcolin, G1
Yanagi, S1
Suzuki, H1
Namiki, T1
Porena, M1
Rosi, P1
Lombi, R1
Valli, PP1
De Mitri, R1
Virgili, G1
Jordan, GH1
Angermeier, KW1
Kaufman, JM1
Borges, FD1
Fitch, WP1
Geller, RA1
Gruber, MB1
Hubbard, JG1
McKay, DL1
Tuttle, JP1
Witten, FR1
Kümmerling, S1
Schubert, J2
Wunderlich, H1
Werner, W1
Culha, M1
Mutlu, N1
Acar, O1
Alici, B1
Gall, H1
Sparwasser, C1
Bähren, W1
Scherb, W1
Holzki, G1
Irion, R1
Pickard, RS1
Oates, CP1
Sethia, KK1
Powell, PH1
De Luca, V1
Tralce, L1
Olivetti, L1
Zambolin, T1
Frego, E1
Simeone, C1
Giambroni, L1
Cosciani Cunico, S1
Chiesa, A1
Schwarzer, JU1
Hofmann, R1
Papadopoulos, I1
Marks, W1
Christiansen, GR1
Weichert-Jacobsen, K1
Pery, M1
Rosenberger, A1
Kaftori, JK1
Vardi, Y1
Schrey, A1
Hu, KN1
Burks, C1
Christy, WC1
Weinberg, JJ1
Badlani, GH1
Shabsigh, R1
Fishman, IJ1
Quesada, ET1
Seale-Hawkins, CK1
Dunn, JK1
Levine, SB1
Althof, SE1
Turner, LA1
Risen, CB1
Bodner, DR1
Kursh, ED1
Resnick, MI1
Girdley, FM1
Bruskewitz, RC1
Feyzi, J1
Graversen, PH1
Gasser, TC1
Desai, KM2
Gingell, JC2
Bookstein, JJ1

Reviews

1 review available for papaverine and Cavernitis, Fibrous

ArticleYear
Transdermal and topical pharmacotherapy for male sexual dysfunction.
    Expert opinion on drug delivery, 2005, Volume: 2, Issue:1

    Topics: Administration, Cutaneous; Administration, Topical; Alprostadil; Androgens; Animals; Erectile Dysfun

2005

Trials

1 trial available for papaverine and Cavernitis, Fibrous

ArticleYear
[Treatment of impotence with intracavernous auto-injections: moxisylyte diminishes the risks compared to papaverine].
    Contraception, fertilite, sexualite (1992), 1993, Volume: 21, Issue:2

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Moxisylyte; Papaverine; Pe

1993

Other Studies

30 other studies available for papaverine and Cavernitis, Fibrous

ArticleYear
Dynamic and morphologic evaluation of erectile dysfunction on penile doppler sonography and contrast cavernosography.
    Nigerian journal of clinical practice, 2017, Volume: 20, Issue:6

    Topics: Adult; Arteries; Contrast Media; Diabetes Complications; Humans; Hypertension; Impotence, Vasculogen

2017
My pet peeve.
    The journal of sexual medicine, 2010, Volume: 7, Issue:4 Pt 1

    Topics: Adrenergic alpha-Antagonists; Advertising; Alprostadil; Atropine; Attitude of Health Personnel; Drug

2010
Current approach to the man with acute phase Peyronie's disease--case presentation and discussion.
    The journal of sexual medicine, 2011, Volume: 8, Issue:6

    Topics: Adult; Arginine; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; H

2011
Experience with intraplaque injection of verapamil for Peyronie's disease.
    The Journal of urology, 2002, Volume: 168, Issue:2

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Injections, Int

2002
Small intestinal submucosa as a tunica albuginea graft material.
    The Journal of urology, 2002, Volume: 168, Issue:3

    Topics: Actins; Alprostadil; Animals; Dose-Response Relationship, Drug; Immunohistochemistry; Intestinal Muc

2002
Incidentally diagnosed Peyronie's disease in men presenting with erectile dysfunction.
    International journal of impotence research, 2004, Volume: 16, Issue:6

    Topics: Adult; Aged; Diabetes Complications; Erectile Dysfunction; Humans; Hypercholesterolemia; Impotence,

2004
The surgical treatment of Peyronie's disease: replacement of plaque by free autograft of buccal mucosa.
    European urology, 2005, Volume: 48, Issue:1

    Topics: Adult; Blood Flow Velocity; Follow-Up Studies; Humans; Injections; Male; Middle Aged; Mouth Mucosa;

2005
The rationale for prostaglandin E1 (alpha-alprostadil) in the management of male impotence.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Alprostadil; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Molsidomine; Moxisylyte; P

1995
[Evaluation of vasculogenic erectile impotence using DICC (dynamic infusion cavernosometry & cevernosography) with intracavernous injection of papaverine].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:6

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Injections; Male; Manometry; Middle Aged; Papaverine; Pen

1993
[Echography during drug-induced erections in the study of penile plastic induration].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 1993, Volume: 65, Issue:4

    Topics: Adult; Aged; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penile Induration; Ultrasonogra

1993
Preoperative evaluation of erectile function with dynamic infusion cavernosometry/cavernosography in patients undergoing surgery for Peyronie's disease: correlation with postoperative results.
    The Journal of urology, 1993, Volume: 150, Issue:4

    Topics: Alprostadil; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penile Induration; Penis; Phent

1993
Evaluation of erectile dysfunction by dynamic infusion cavernosometry and cavernosography (DICC). Multi-institutional study.
    Urology, 1993, Volume: 41, Issue:5

    Topics: Blood Pressure; Diabetic Angiopathies; Erectile Dysfunction; Humans; Male; Manometry; Middle Aged; P

1993
Peyronie's disease. Investigation of staging, erectile failure and operative management.
    International urology and nephrology, 1995, Volume: 27, Issue:5

    Topics: Erectile Dysfunction; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Papaverine; Penile

1995
Coincidence of induratio penis plastica and erectile dysfunction.
    Urologia internationalis, 1998, Volume: 60, Issue:2

    Topics: Adult; Aged; Diagnosis, Differential; Erectile Dysfunction; Follow-Up Studies; Humans; Injections, I

1998
Patient-partner satisfaction with intracavernous medication supported with oral agents in selected cases of Peyronie's disease. A ten-month follow-up study.
    International urology and nephrology, 1999, Volume: 31, Issue:2

    Topics: Adult; Alprostadil; Colchicine; Drug Administration Routes; Drug Therapy, Combination; Follow-Up Stu

1999
[Long-term results of corpus cavernosum auto-injection therapy in treatment of patients with chronic erectile dysfunction].
    Der Urologe. Ausg. A, 1992, Volume: 31, Issue:1

    Topics: Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Injections; Long-Term Care; Male; Ma

1992
The role of colour duplex ultrasonography in the diagnosis of vasculogenic impotence.
    British journal of urology, 1991, Volume: 68, Issue:5

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Induration; Penis;

1991
[Echography versus nuclear magnetic resonance in the preoperative dynamic evaluation of plastic penile induration].
    Archivio italiano di urologia, nefrologia, andrologia : organo ufficiale dell'Associazione per la ricerca in urologia = Urological, nephrological, and andrological sciences, 1991, Volume: 63 Suppl 2

    Topics: Adult; Aged; Evaluation Studies as Topic; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pap

1991
Purulent corporeal cavernositis secondary to papaverine-induced priapism.
    The Journal of urology, 1991, Volume: 146, Issue:3

    Topics: Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Papaverine; Penile Induration; Priapism

1991
[Cavernosography using digital luminescence radiography (DLR) in the diagnosis of venous induced erectile function and of diseases of the corpus cavernosum].
    Der Urologe. Ausg. A, 1991, Volume: 30, Issue:1

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Diseases; Penile Er

1991
Intracorporeal calcifications after self-injection of papaverine.
    Radiology, 1990, Volume: 176, Issue:1

    Topics: Adult; Calcinosis; Humans; Injections; Male; Middle Aged; Papaverine; Penile Induration; Ultrasonogr

1990
[Prostaglandin E1 injection in erectile dysfunction. Current diagnostic and therapeutic possibilities].
    Fortschritte der Medizin, 1990, Oct-20, Volume: 108, Issue:30

    Topics: Alprostadil; Erectile Dysfunction; Humans; Injections; Male; Papaverine; Penile Induration; Priapism

1990
Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection.
    The Journal of urology, 1987, Volume: 138, Issue:2

    Topics: Aged; Drug Combinations; Erectile Dysfunction; Fibrosis; Humans; Male; Middle Aged; Papaverine; Peni

1987
Utility of Rigiscan and papaverine in diagnosis of erectile impotence.
    Urology, 1988, Volume: 31, Issue:6

    Topics: Erectile Dysfunction; Evaluation Studies as Topic; Humans; Male; Monitoring, Physiologic; Papaverine

1988
Evaluation of vasculogenic erectile impotence using penile duplex ultrasonography.
    The Journal of urology, 1989, Volume: 142, Issue:6

    Topics: Adult; Aged; Arteries; Ejaculation; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Pen

1989
Side effects of self-administration of intracavernous papaverine and phentolamine for the treatment of impotence.
    The Journal of urology, 1989, Volume: 141, Issue:1

    Topics: Adult; Aged; Drug Therapy, Combination; Erectile Dysfunction; Humans; Injections; Liver Function Tes

1989
Intracavernous self-injection for impotence: a long-term therapeutic option? Experience in 78 patients.
    The Journal of urology, 1988, Volume: 140, Issue:5

    Topics: Consumer Behavior; Drug Combinations; Erectile Dysfunction; Humans; Male; Middle Aged; Pain; Papaver

1988
Penile corporeal fibrosis complicating papaverine self-injection therapy for erectile impotence.
    European urology, 1988, Volume: 15, Issue:1-2

    Topics: Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penile Induration; Sel

1988
Out-patient assessment of penile curvature.
    British journal of urology, 1987, Volume: 60, Issue:5

    Topics: Ambulatory Care; Humans; Male; Papaverine; Penile Erection; Penile Induration

1987
Cavernosal venocclusive insufficiency in male impotence: evaluation of degree and location.
    Radiology, 1987, Volume: 164, Issue:1

    Topics: Aged; Blood Pressure; Erectile Dysfunction; Humans; Male; Manometry; Middle Aged; Papaverine; Penile

1987