papaverine has been researched along with Carotid Stenosis in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension." | 9.09 | Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001) |
| "This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension." | 5.09 | Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001) |
| "Two patients showed signs of elevated intracranial pressure after the procedures and also had ASrO2 readings exceeding 15%; measures to lower arterial hypertension reduced SrO2 in these patients." | 2.72 | [Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty]. ( Carrero, E; Fàbregas, N; Fontanals, J; Rodríguez, L; Salvador, L; Valero, R, 2006) |
| "10% glycerol solution was able to prevent microvascular alterations due to BCCAO protecting cerebral tissue." | 1.35 | Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol. ( Colantuoni, A; Lapi, D; Marchiafava, PL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, QY | 1 |
| Xu, WL | 1 |
| Zhang, Y | 1 |
| Lu, PS | 1 |
| Yuan, ZC | 1 |
| Zhan, LP | 1 |
| Wang, P | 1 |
| Lu, XY | 1 |
| Cheng, B | 1 |
| Rodríguez, L | 1 |
| Salvador, L | 1 |
| Valero, R | 1 |
| Carrero, E | 1 |
| Fontanals, J | 1 |
| Fàbregas, N | 1 |
| Lapi, D | 1 |
| Marchiafava, PL | 1 |
| Colantuoni, A | 1 |
| Joshi, S | 1 |
| Hashimoto, T | 1 |
| Ostapkovich, N | 1 |
| Pile-Spellman, J | 1 |
| Duong, DH | 1 |
| Hacein-Bey, L | 1 |
| Hacien-Bey, L | 1 |
| Marshall, RS | 1 |
| James, DJ | 1 |
| Young, WL | 1 |
2 trials available for papaverine and Carotid Stenosis
| Article | Year |
|---|---|
[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty].
Topics: Aged; Angioplasty, Balloon; Blood Pressure; Brain Ischemia; Carotid Artery, Internal; Carotid Stenos | 2006 |
Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension.
Topics: Aged; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Female; Functional Laterality | 2001 |
2 other studies available for papaverine and Carotid Stenosis
| Article | Year |
|---|---|
Intravascular infusion of lidocaine: a novel way to relieve sudden internal carotid artery occlusion in embolization of intracranial aneurysms.
Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Embolization, Therapeutic; Female; Humans; Infusio | 2012 |
Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol.
Topics: Animals; Blood Flow Velocity; Capillary Permeability; Carotid Artery, Common; Carotid Stenosis; Cell | 2008 |