Page last updated: 2024-11-02

papaverine and Carotid Artery Narrowing

papaverine has been researched along with Carotid Artery Narrowing in 4 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension."9.09Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001)
"This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension."5.09Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001)
"Two patients showed signs of elevated intracranial pressure after the procedures and also had ASrO2 readings exceeding 15%; measures to lower arterial hypertension reduced SrO2 in these patients."2.72[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty]. ( Carrero, E; Fàbregas, N; Fontanals, J; Rodríguez, L; Salvador, L; Valero, R, 2006)
"10% glycerol solution was able to prevent microvascular alterations due to BCCAO protecting cerebral tissue."1.35Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol. ( Colantuoni, A; Lapi, D; Marchiafava, PL, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, QY1
Xu, WL1
Zhang, Y1
Lu, PS1
Yuan, ZC1
Zhan, LP1
Wang, P1
Lu, XY1
Cheng, B1
Rodríguez, L1
Salvador, L1
Valero, R1
Carrero, E1
Fontanals, J1
Fàbregas, N1
Lapi, D1
Marchiafava, PL1
Colantuoni, A1
Joshi, S1
Hashimoto, T1
Ostapkovich, N1
Pile-Spellman, J1
Duong, DH1
Hacein-Bey, L1
Hacien-Bey, L1
Marshall, RS1
James, DJ1
Young, WL1

Trials

2 trials available for papaverine and Carotid Artery Narrowing

ArticleYear
[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Aged; Angioplasty, Balloon; Blood Pressure; Brain Ischemia; Carotid Artery, Internal; Carotid Stenos

2006
Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension.
    Journal of neurosurgical anesthesiology, 2001, Volume: 13, Issue:2

    Topics: Aged; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Female; Functional Laterality

2001

Other Studies

2 other studies available for papaverine and Carotid Artery Narrowing

ArticleYear
Intravascular infusion of lidocaine: a novel way to relieve sudden internal carotid artery occlusion in embolization of intracranial aneurysms.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:2

    Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Embolization, Therapeutic; Female; Humans; Infusio

2012
Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol.
    Journal of vascular research, 2008, Volume: 45, Issue:2

    Topics: Animals; Blood Flow Velocity; Capillary Permeability; Carotid Artery, Common; Carotid Stenosis; Cell

2008