papaverine has been researched along with Cardiac Hypertrophy in 9 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the role played by angiotensin II (AII) in the development of prehypertensive vascular hypertrophy in the spontaneously hypertensive rat (SHR) and to determine whether normalization of prehypertensive vascular hypertrophy attenuates the development of hypertension." | 3.69 | Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats. ( Black, MJ; Bobik, A; Kanellakis, P, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HEIMANN, W | 1 |
| WILBRANDT, W | 1 |
| HANNA, C | 1 |
| ESPLUGUES, J | 1 |
| BRUGGER, A | 1 |
| HUESO, E | 1 |
| SOTO, L | 1 |
| Black, MJ | 1 |
| Kanellakis, P | 1 |
| Bobik, A | 1 |
| McNamara, RF | 1 |
| Schmid, PG | 2 |
| Schmidt, JA | 1 |
| Lund, DD | 1 |
| Bhatnagar, RK | 1 |
| Mayer, HE | 1 |
| Mark, AL | 1 |
| Heistad, DD | 1 |
| Abboud, FM | 1 |
| Antony, I | 1 |
| Nitenberg, A | 1 |
| Foult, JM | 1 |
| Severin, SE | 1 |
| Zoli, I | 1 |
| Baroncini, S | 1 |
| Cornia, GL | 1 |
| Donato, S | 1 |
| Minore, G | 1 |
| Pigini, G | 1 |
| Pretolani, E | 1 |
9 other studies available for papaverine and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Studies on coronary-dilatating effects on Langendorff's preparation and its interpretation on the basis of competitive antagonism].
Topics: Caffeine; Cardiomegaly; Heart; Humans; Khellin; Papaverine; Theophylline | 1954 |
Papaverine analogs. VII. Studies on the time of onset of coronary dilator action.
Topics: Cardiomegaly; Coronary Vessels; Heart; Humans; Papaverine | 1959 |
[INVERSION OF THE CORONARY DILATOR EFFECT OF SOME DRUGS BY ERGOTAMINE TARTRATE].
Topics: Animals; Blood Circulation; Cardiomegaly; Coronary Vessels; Dipyridamole; Dogs; Ergotamine; Papaveri | 1963 |
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensiv | 1997 |
Humoral regulation of vascular resistance after 30 days of pulmonary artery constriction.
Topics: Angiotensin II; Animals; Cardiomegaly; Catecholamines; Dopamine; Epinephrine; Guinea Pigs; Heart Fai | 1979 |
Differences in the regulation of vascular resistance in guinea pigs with right and left heart failure.
Topics: Angiotensin II; Animals; Aorta; Arterial Occlusive Diseases; Blood Gas Analysis; Cardiomegaly; Elect | 1977 |
[Coronary reserve in treated hypertension with persistent left ventricular hypertrophy].
Topics: Cardiomegaly; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Hypertension; Middle Age | 1991 |
[Basic directions in the study of the biochemistry of the myocardium].
Topics: Adaptation, Physiological; Animals; Camphor; Cardiac Glycosides; Cardiomegaly; Cardiovascular Diseas | 1967 |
[Therapeutic possibilities in coronary disease].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Arteriosclerosis; Cardiomegaly; Coronary Disease | 1973 |