papaverine has been researched along with Carcinoma, Renal Cell in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human renal cell carcinomas display a characteristically high degree of intrinsic chemoresistance to a multitude of chemotherapeutic agents." | 1.28 | Effects of calcium antagonists in multidrug resistant primary human renal cell carcinomas. ( Alken, PM; Keilhauer, G; Kössig, J; Mickisch, GH; Schlick, E; Tschada, RK, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mickisch, GH | 1 |
| Kössig, J | 1 |
| Keilhauer, G | 1 |
| Schlick, E | 1 |
| Tschada, RK | 1 |
| Alken, PM | 1 |
1 other study available for papaverine and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Effects of calcium antagonists in multidrug resistant primary human renal cell carcinomas.
Topics: Calcium; Carcinoma, Renal Cell; Chemical Phenomena; Chemistry; Dihydropyridines; Diltiazem; Drug Res | 1990 |