papaverine has been researched along with Bronchial Spasm in 25 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The tested medication has a favorable therapeutic spectrum as a result of the low dosage of the individual substances." | 2.66 | [Bronchospasmolytic effectiveness of controlled drug combinations]. ( Forche, G; Harnoncourt, K; Zenker, G, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (96.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Temple, DL | 1 |
| Yevich, JP | 1 |
| Catt, JD | 1 |
| Owens, D | 1 |
| Hanning, C | 1 |
| Covington, RR | 1 |
| Seidehamel, RJ | 1 |
| Dungan, KW | 1 |
| MERCIER, F | 2 |
| SESTIER, MR | 1 |
| RICHAUD, L | 1 |
| FRANDSEN, VA | 1 |
| ROKSETH, R | 1 |
| KJORSTAD, H | 1 |
| SKAGA, E | 1 |
| STORSTEIN, O | 1 |
| ZIELINSKI, J | 1 |
| KOZIOROWSKI, A | 1 |
| MERCIER, J | 1 |
| COLIN, J | 1 |
| Biernacki, W | 1 |
| Bestry-Fus, I | 1 |
| Figielski, G | 1 |
| Marmo, E | 1 |
| McAtamney, D | 1 |
| McKaigue, JP | 1 |
| Linée, P | 1 |
| Lacroix, P | 1 |
| Laville, MP | 1 |
| Le Pollès, JB | 1 |
| Kukes, VG | 1 |
| Shvarts, GIa | 1 |
| Milovanova, NM | 1 |
| Chang, WW | 1 |
| Zisel'man, SB | 1 |
| Forche, G | 1 |
| Zenker, G | 1 |
| Harnoncourt, K | 1 |
| Offermeier, J | 1 |
| Brandt, HD | 1 |
| Marquardt, H | 1 |
| Farmer, JB | 1 |
| Lehrer, DN | 1 |
| Giertz, H | 1 |
| Hahn, F | 2 |
| Bernauer, W | 2 |
| Kovács, IB | 1 |
| Görög, P | 1 |
| Zaslavskaia, RM | 1 |
| Bartsch, R | 1 |
| Nowak, R | 1 |
| Femmer, K | 1 |
| Stade, K | 1 |
| Mahlstedt, J | 1 |
| Resch-Bollhagen, S | 1 |
| Beck, E | 1 |
| Weiss, S | 1 |
| Scherrer, M | 1 |
| Dutta, D | 1 |
| Bhargava, KC | 1 |
| Chakravarti, RN | 1 |
| Dhall, SR | 1 |
| Groll, H | 1 |
| Cheshik, VG | 1 |
| Golubov, EF | 1 |
| Kulka, F | 1 |
1 trial available for papaverine and Bronchial Spasm
| Article | Year |
|---|---|
[Bronchospasmolytic effectiveness of controlled drug combinations].
Topics: Airway Resistance; Aminophylline; Atropine Derivatives; Blood Pressure; Bronchial Spasm; Bronchodila | 1986 |
24 other studies available for papaverine and Bronchial Spasm
| Article | Year |
|---|---|
Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Chemical Phenomena; Chemistry; Female; Guinea Pigs; | 1980 |
[Effect of papaverine derivatives on histaminic bronchospasm in the guinea pig].
Topics: Bronchi; Bronchial Diseases; Bronchial Spasm; Disease; Guinea Pigs; Papaverine | 1952 |
[Research on the action of various antiasthmatic and antispasmodic substances on experimental bronchospasm].
Topics: Anti-Asthmatic Agents; Atropine; Bronchi; Bronchial Diseases; Bronchial Spasm; Disease; Epinephrine; | 1953 |
Papaverine hydrochloride and the pulmonary circulation, with a note on the effect of bronchospasm.
Topics: Blood Circulation; Bronchial Spasm; Humans; Papaverine; Pulmonary Circulation | 1960 |
COMBINED RESPIRATORY AND METABOLIC ACIDOSIS CAUSED BY BRONCHOSPASM IN ANAPHYLACTIC SHOCK.
Topics: Acidosis; Acidosis, Respiratory; Aminopyrine; Anaphylaxis; Bronchial Spasm; Bronchodilator Agents; D | 1964 |
[Effect of papaverine on histamine and acetylcholine bronchospasms of the guinea pig].
Topics: Acetylcholine; Bronchial Spasm; Guinea Pigs; Histamine; Papaverine; Parasympatholytics | 1950 |
[Spirographic indicators and theophylline levels in the blood and saliva after oral administration of 2 euphylline preparations in patients with reversible bronchial obstruction].
Topics: Administration, Oral; Adult; Aminophylline; Biological Availability; Bronchi; Bronchial Spasm; Bronc | 1982 |
[Pharmacodynamic aspects of reproterol].
Topics: Albuterol; Animals; Atropine; Bronchi; Bronchial Spasm; Bronchodilator Agents; Clenbuterol; Drug Com | 1981 |
Severe bronchospasm relieved by papaverine?
Topics: Bronchial Spasm; Child; Humans; Intraoperative Complications; Kidney Transplantation; Male; Papaveri | 2000 |
[Effect of L-eburnamonine on bronchial respiratory resistance in the anesthetized guinea pig. Comparison with vincamine].
Topics: Airway Resistance; Anesthesia; Animals; Atropine; Brompheniramine; Bronchi; Bronchial Spasm; Female; | 1978 |
[Efficacy of tiphen].
Topics: Adult; Aged; Animals; Arteriosclerosis; Bronchial Spasm; Female; Gastrointestinal Diseases; Guinea P | 1979 |
Mode of antagonism between beta-adrenergic drugs and prostaglandin F2-alpha.
Topics: Adrenergic beta-Antagonists; Animals; Bronchial Spasm; Dose-Response Relationship, Drug; Guinea Pigs | 1974 |
[On the problem of pathogenesis of vagus reflex bradykinin tachypnea].
Topics: Animals; Aspirin; Bradykinin; Bronchial Spasm; Dyspnea; Guinea Pigs; Isoproterenol; Lung; Papaverine | 1966 |
The effect of isoprenaline on the contraction of smooth muscle produced by histamine, acetylcholine or other agents.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Bronchial Spasm; Chlorpheniramine; Creatine; Drug Anta | 1966 |
On the cause of the different sensitivity to antihistaminics (mepyramine) of anaphylactic, histamine, and anaphylatoxin shock.
Topics: Anaphylaxis; Animals; Bronchi; Bronchial Spasm; Guinea Pigs; Histamine; Histamine H1 Antagonists; Lu | 1968 |
Bronchoconstrictor effect of endotoxin in guinea-pig; the protective effect of antihistamine and anti-inflammatory compounds.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure Determination; Bronchi; Bro | 1968 |
[Antiserotonin action of several pharmacological substances on the vessels of the lungs and bronchi].
Topics: Aminophylline; Analgesics; Animals; Atropine; Blood Pressure; Bronchial Spasm; Epinephrine; Fibrinol | 1969 |
[Pharmacology of the new antihistaminic 9,9-dioxopromethazine (Prothanon)].
Topics: Abnormalities, Drug-Induced; Anesthetics, Local; Animals; Behavior, Animal; Blood Pressure; Bronchia | 1970 |
Synergistic effects of adrenaline and mepyramine on the anaphylactic reactions of the bronchi and pulmonary vessels in the guinea pig heart-lung-preparation.
Topics: Anaphylaxis; Animals; Blood Pressure; Bronchial Spasm; Cardiac Output; Drug Synergism; Epinephrine; | 1970 |
[High-dosage intravenous eupaverine-(papaverine-)injection in bronchial asthma].
Topics: Adult; Asthma; Blood Gas Analysis; Blood Pressure; Bronchial Spasm; Electrocardiography; Female; Hem | 1973 |
Therapeutic studies in experimental amniotic fluid embolism in rabbits.
Topics: Anaphylaxis; Animals; Atropine; Bronchial Spasm; Disease Models, Animal; Electrocardiography; Emboli | 1970 |
[Therapeutic possibilities of spastic bronchitis in infancy and early childhood in general practice].
Topics: Analgesics; Bronchial Spasm; Bronchitis; Child, Preschool; Humans; Infant; Papaverine; Thymol | 1967 |
[Bronchospasm as a complication of general anesthesia].
Topics: Aminophylline; Anesthesia, General; Atropine; Bronchial Spasm; Heart Massage; Humans; Lung; Lung Dis | 1968 |
[Indications for prevention and treatment of pulmonary complications in surgery].
Topics: Atropine; Bronchial Spasm; Papaverine; Phenobarbital; Postoperative Complications; Pulmonary Atelect | 1966 |