papaverine has been researched along with Bronchial Hyperreactivity in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matera, MG | 1 |
| Calzetta, L | 1 |
| Parascandolo, V | 1 |
| Curradi, G | 1 |
| Rogliani, P | 1 |
| Cazzola, M | 1 |
| Iwamae, S | 1 |
| Tsukagoshi, H | 1 |
| Hisada, T | 1 |
| Uno, D | 1 |
| Mori, M | 1 |
| Chiba, Y | 1 |
| Sakai, H | 1 |
| Misawa, M | 1 |
3 other studies available for papaverine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi.
Topics: Bronchi; Bronchial Hyperreactivity; Carbachol; Histamine; Humans; Immunization, Passive; In Vitro Te | 2009 |
A possible involvement of oxidative lung injury in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs.
Topics: Acetophenones; Aminophylline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchial H | 1998 |
Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats.
Topics: Acetylcholine; Amides; Animals; Antigens; Biological Transport; Bronchi; Bronchial Hyperreactivity; | 2001 |