papaverine has been researched along with Breast Cancer in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine has more cytotoxic effect on MCF-7 CSCs in comparison with parental cells, while CSCs population of MDA-MB-231 is more resistant to papaverine compared with MDA-MB-231 cells." | 5.42 | Cell cycle arrest and apoptogenic properties of opium alkaloids noscapine and papaverine on breast cancer stem cells. ( Ghahremani, MH; Kouhsari, SM; Majdzadeh, M; Ostad, SN; Sajadian, S; Vatankhah, M, 2015) |
| "Papaverine has more cytotoxic effect on MCF-7 CSCs in comparison with parental cells, while CSCs population of MDA-MB-231 is more resistant to papaverine compared with MDA-MB-231 cells." | 1.42 | Cell cycle arrest and apoptogenic properties of opium alkaloids noscapine and papaverine on breast cancer stem cells. ( Ghahremani, MH; Kouhsari, SM; Majdzadeh, M; Ostad, SN; Sajadian, S; Vatankhah, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sajadian, S | 1 |
| Vatankhah, M | 1 |
| Majdzadeh, M | 1 |
| Kouhsari, SM | 1 |
| Ghahremani, MH | 1 |
| Ostad, SN | 1 |
| Rubis, B | 2 |
| Kaczmarek, M | 1 |
| Szymanowska, N | 1 |
| Galezowska, E | 1 |
| Czyrski, A | 2 |
| Juskowiak, B | 1 |
| Hermann, T | 2 |
| Rybczynska, M | 2 |
| Sledź, D | 1 |
| Fontana, JA | 1 |
| Miksis, G | 1 |
| Miranda, DM | 1 |
| Durham, JP | 1 |
4 other studies available for papaverine and Breast Cancer
| Article | Year |
|---|---|
Cell cycle arrest and apoptogenic properties of opium alkaloids noscapine and papaverine on breast cancer stem cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Dose-Respons | 2015 |
The biological activity of G-quadruplex DNA binding papaverine-derived ligand in breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Response Relationship, | 2009 |
Biopharmaceutical characterization of some new papaverine decomposition products.
Topics: Antineoplastic Agents, Phytogenic; Biopharmaceutics; Breast Neoplasms; Cell Line, Tumor; Chromatogra | 2011 |
Inhibition of human mammary carcinoma cell proliferation by retinoids and intracellular cAMP-elevating compounds.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cell Division; Cell Line; Cholera Toxin; C | 1987 |