papaverine has been researched along with Brain Injuries, Traumatic in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Brain Injuries, Traumatic: A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The IL-6 antagonist LMT-28 prevented impairment of cerebral autoregulation and hippocampal CA1 and CA3 neuronal necrosis after FPI." | 3.91 | Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Necrosis After Traumatic Brain Injury Through Inhibition of ET-1, ERK MAPK and IL-6 Upregulation in Pigs. ( Armstead, WM; Curvello, V; Hekierski, H; Pastor, P, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Saglam, E | 1 |
| Zırh, S | 1 |
| Aktas, CC | 1 |
| Muftuoglu, SF | 1 |
| Bilginer, B | 1 |
| Curvello, V | 1 |
| Pastor, P | 1 |
| Hekierski, H | 1 |
| Armstead, WM | 2 |
| Vavilala, MS | 1 |
3 other studies available for papaverine and Brain Injuries, Traumatic
| Article | Year |
|---|---|
Papaverine provides neuroprotection by suppressing neuroinflammation and apoptosis in the traumatic brain injury via RAGE- NF-
Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Inflammation; Male; Mice; Neuroprotective Agents; NF- | 2021 |
Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Necrosis After Traumatic Brain Injury Through Inhibition of ET-1, ERK MAPK and IL-6 Upregulation in Pigs.
Topics: Administration, Inhalation; Animals; Animals, Newborn; Brain Injuries, Traumatic; Disease Models, An | 2019 |
Cerebral Perfusion Pressure Directed-Therapy Modulates Cardiac Dysfunction After Traumatic Brain Injury to Influence Cerebral Autoregulation in Pigs.
Topics: Animals; Animals, Newborn; Arterial Pressure; Brain Injuries, Traumatic; Cerebrovascular Circulation | 2019 |