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papaverine and Body Weight

papaverine has been researched along with Body Weight in 19 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"To examine the role played by angiotensin II (AII) in the development of prehypertensive vascular hypertrophy in the spontaneously hypertensive rat (SHR) and to determine whether normalization of prehypertensive vascular hypertrophy attenuates the development of hypertension."3.69Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats. ( Black, MJ; Bobik, A; Kanellakis, P, 1997)
" We found a shift in the dose-response curve of only phosphodiesterase 5 inhibitors."1.32The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips. ( Bagcivan, I; Gokce, G; Kilicarslan, H; Sarac, B; Sarioglu, Y; Yildirim, S, 2003)
"Treatment with melatonin (EC(50) 4."1.32Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum. ( Ayanğolu-Dülger, G; Paskaloglu, K; Sener, G, 2004)
"Allometric scaling is an empirical examination of the relationships between the pharmacokinetic parameters and size (usually body weight, ratio of organ- and body weight, breathing number, etc."1.30[Interspecies allometric scaling in pharmacokinetics of drugs]. ( Sylvia, M, 1998)
" The naltrexone stimulus-generalization curve and dose-response curve for loss of body weight were shifted to the left by IBMX and Ro 20-1724, which produce quasi-withdrawal, but not by papaverine, which does not."1.28Phosphodiesterase inhibitors potentiate opiate-antagonist discrimination by morphine-dependent rats. ( Holtzman, SG, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's8 (42.11)18.2507
2000's4 (21.05)29.6817
2010's0 (0.00)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Adamchuk, D1
Kuziev, M1
Gurman, E1
Niyazmetov, B1
Kilicarslan, H1
Yildirim, S1
Bagcivan, I1
Gokce, G1
Sarac, B1
Sarioglu, Y1
Martinez-Lemus, LA1
Hester, RK1
Becker, EJ1
Ramirez, GA1
Odom, TW1
Tatchum-Talom, R1
Martin, DS1
Paskaloglu, K1
Sener, G1
Ayanğolu-Dülger, G1
Lai, FM1
Tanikella, T1
Thibault, L1
Chan, PS1
Cervoni, P1
Sikorski, BW1
James, GM1
Glance, SD1
Hodgson, WC1
King, RG1
Fuentes, J1
Eddy, FB1
Black, MJ1
Kanellakis, P1
Bobik, A1
Chew, HG1
Segal, SS1
Grossman, HJ1
Grossman, VL1
Bhathal, PS1
Priest, RM1
Robertson, TP1
Leach, RM1
Ward, JP1
Sylvia, M1
Kirby, MJ1
Leighton, M1
Turner, P1
Henrion, D1
Chillon, JM1
Hoffman, M1
Capdeville-Atkinson, C1
Atkinson, J1
Holtzman, SG1
Lemke, H1
Oettel, M1
Chemnitius, KH1
Burberi, S1
Silvestrini, B1
Dewey, WL1
Malone, MH1

Other Studies

19 other studies available for papaverine and Body Weight

ArticleYear
INFLUENCE OF PAPAVERINE AND COMMERCIAL DIETARY SUPPLEMENTS ON BLOOD GLUCOSE AND BODY WEIGHT IN OBESE DOGS.
    Georgian medical news, 2023, Issue:336

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Dietary Supplements; Obesity; Papaverine

2023
The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Amrinone; Animals; Body Weight; Calcium; Creatinine; Dose-Response Relationship, Drug; Electric Stim

2003
Pulmonary artery vasoactivity in broiler and Leghorn chickens: an age profile.
    Poultry science, 2003, Volume: 82, Issue:12

    Topics: Acetylcholine; Aging; Animals; Body Weight; Chick Embryo; Chickens; Endothelin-1; Organ Size; Papave

2003
Tempol improves vascular function in the mesenteric vascular bed of senescent rats.
    Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:3

    Topics: Administration, Oral; Aging; Animals; Blood Pressure; Body Weight; Cyclic N-Oxides; Dose-Response Re

2004
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
    European journal of pharmacology, 2004, Sep-24, Volume: 499, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental

2004
Effects of different stages of aortic coarctation hypertension on aortic contraction and relaxation in rats.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Body Weight; Hypertension; Isoproterenol; Ligatio

1980
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3

    Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; I

1993
Effect of manipulation of the renin-angiotensin system in control of drinking in juvenile Atlantic salmon (Salmo salar L) in fresh water and after transfer to sea water.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1997, Volume: 167, Issue:6

    Topics: Angiotensin II; Animals; Body Weight; Chlorides; Drinking; Fresh Water; Papaverine; Renin-Angiotensi

1997
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
    Journal of hypertension, 1997, Volume: 15, Issue:9

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensiv

1997
Arterial morphology and blood volumes of rats following 10-14 weeks of tail suspension.
    Medicine and science in sports and exercise, 1997, Volume: 29, Issue:10

    Topics: Analysis of Variance; Animals; Blood Volume; Body Weight; Female; Femoral Artery; Hindlimb; Hindlimb

1997
The effect of hepatocyte enlargement on the hemodynamic characteristics of the isolated perfused rat liver preparation.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Hypertrophy; Hypotonic Solutions; In Vitro T

1998
Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Body Weight; Cromakalim; Dinoprost; Dose-Response Relationship, Drug; Heart Ventricles; Hem

1998
[Interspecies allometric scaling in pharmacokinetics of drugs].
    Acta pharmaceutica Hungarica, 1998, Volume: 68, Issue:6

    Topics: Animals; Body Weight; Cats; Dogs; Drug Combinations; Humans; Mice; Organ Size; Papaverine; Parasympa

1998
The influence of premedication, anaesthesia, age and weight on glucose uptake into human isolated skeletal muscle.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:2

    Topics: Adult; Age Factors; Aged; Anesthesia; Atropine; Body Weight; Female; Glucose; Glycogen; Humans; Male

1976
Decrease in endothelium-dependent relaxation in the mesenteric arterial bed following vascular calcium overload produced by vitamin D3 and nicotine in rats.
    Life sciences, 1991, Volume: 49, Issue:8

    Topics: Animals; Body Weight; Calcium; Carbachol; Cholecalciferol; Endothelium; Histamine; Male; Muscle Rela

1991
Phosphodiesterase inhibitors potentiate opiate-antagonist discrimination by morphine-dependent rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Body Weight; D

1989
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
    Archiv fur experimentelle Veterinarmedizin, 1974, Volume: 28, Issue:5

    Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease

1974
Preventive action of proxazole in experimentally induced renal hypertension in rats.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:3

    Topics: Animals; Arteries; Blood Pressure; Body Weight; Ethylamines; Female; Hypertension, Renal; Male; Neph

1971
Pharmacologic and toxicologic evaluation of 2-(N-tetradecyl-N-ethylamino)-2-methyl-1,3-propanediol hydrochloride, an inhibitor of intestinal absorption.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:1

    Topics: Animals; Anti-Infective Agents, Local; Appetite Depressants; Basal Metabolism; Biological Transport,

1968