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papaverine and Blood Pressure, Low

papaverine has been researched along with Blood Pressure, Low in 23 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension."9.09Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001)
"Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death."5.36Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010)
"Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus."5.33Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006)
"This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension."5.09Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001)
" Papaverine (10 mg/kg) caused hypotension and increased PRA."3.66Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau. ( Lunde, LG; Nishimura, H; Zucker, A, 1979)
"Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death."1.36Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010)
"Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus."1.33Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006)
"In yohimbine-treated dogfish, papaverine treatment elicited marked decreases in PCA, RS, and Q, and increases in plasma Ang II and catecholamines."1.30Cardiovascular control via angiotensin II and circulating catecholamines in the spiny dogfish, Squalus acanthias. ( Bernier, NJ; Gilmour, KM; Perry, SF; Takei, Y, 1999)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199010 (43.48)18.7374
1990's5 (21.74)18.2507
2000's6 (26.09)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singla, N1
Mathuriya, SN1
Mohindra, S1
Umredkar, AA1
Adhikari, S1
Gupta, SK1
Gupta, V1
Baltaci, B1
Basar, H1
Ozcan, A1
Gulhan, Y1
Aytunur, CS1
Chowdhury, FH1
Haque, MR1
Butler, DG1
Zhang, DH1
Villadiego, R1
Oudit, GY1
Youson, JH1
Cadinouche, MZ1
ENDERS, A1
SCHMIDT, L1
MISKO, JC1
Mikhailichenko, LA1
Timkina, MI1
Rath, GP1
Prabhakar, H1
Dash, HH1
Suri, A1
Gygax, P4
Wiernsperger, N4
Cernacek, P1
Stewart, DJ1
Levy, M1
Svensson, LG1
Hess, KR1
D'Agostino, RS1
Entrup, MH1
Hreib, K1
Kimmel, WA1
Nadolny, E1
Shahian, DM1
Shiode, N1
Kato, M1
Nakayama, K1
Shinohara, K1
Kurokawa, J1
Yamagata, T1
Matsuura, H1
Kajiyama, G1
Bernier, NJ2
Kaiya, H1
Takei, Y2
Perry, SF2
Gilmour, KM1
Osadchiĭ, LI1
Balueva, TV1
Sergeev, IV1
Joshi, S1
Hashimoto, T1
Ostapkovich, N1
Pile-Spellman, J1
Duong, DH1
Hacein-Bey, L1
Hacien-Bey, L1
Marshall, RS1
James, DJ1
Young, WL1
Benzi, G1
Nishimura, H1
Lunde, LG1
Zucker, A1
Danzeisen, M1
Schweizer, A1
Grandchamp, A1
Ayer, G1
Truniger, B1
Clarke, RS1
Dundee, JW1
Carson, IW1
Arora, MV1
McCaughey, W1

Trials

2 trials available for papaverine and Blood Pressure, Low

ArticleYear
Reduction of neurologic injury after high-risk thoracoabdominal aortic operation.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:1

    Topics: Adult; Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cardiopulmonary Bypass; Cerebros

1998
Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension.
    Journal of neurosurgical anesthesiology, 2001, Volume: 13, Issue:2

    Topics: Aged; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Female; Functional Laterality

2001

Other Studies

21 other studies available for papaverine and Blood Pressure, Low

ArticleYear
Severe hypotension with intracisternal application of papaverine after clipping of an intracranial aneurysm.
    Surgical neurology, 2009, Volume: 72, Issue:6

    Topics: Acute Kidney Injury; Carotid Artery Diseases; Cerebral Angiography; Cisterna Magna; Fatal Outcome; H

2009
Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report.
    Journal of neurosurgery, 2010, Volume: 113, Issue:4

    Topics: Bradycardia; Cisterna Magna; Fatal Outcome; Glasgow Coma Scale; Heart Arrest; Hemodynamics; Humans;

2010
Severe hypotension, cardiac arrest, and death after intracisternal instillation of papaverine during anterior communicating artery aneurysm clipping. A case report.
    Acta neurochirurgica, 2013, Volume: 155, Issue:2

    Topics: Fatal Outcome; Female; Heart Arrest; Humans; Hypotension; Instillation, Drug; Intracranial Aneurysm;

2013
Response by the corpuscles of Stannius to hypotensive stimuli in three divergent ray-finned fishes (Amia calva, Anguilla rostrata, and Catastomus commersoni): cardiovascular and morphological changes.
    General and comparative endocrinology, 2003, Jun-15, Volume: 132, Issue:2

    Topics: Anguilla; Animals; Blood Pressure; Calibration; Cytoplasmic Granules; Elasmobranchii; Endocrine Glan

2003
[Increase of the hypotensive effects of papaverine by epinephrine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1952, Volume: 216, Issue:4

    Topics: Epinephrine; Humans; Hypotension; Papaverine

1952
SELECTIVE CEREBRAL HYPOTHERMIA: PHYSIOLOGY AND TECHNIC.
    Annals of surgery, 1965, Volume: 161

    Topics: Blood; Brain; Brain Ischemia; Dogs; Electrocardiography; Hydrogen-Ion Concentration; Hypotension; Hy

1965
Microvessels of hamster buccal pouch under conditions of reduced systemic blood pressure.
    Bulletin of experimental biology and medicine, 2004, Volume: 138, Issue:6

    Topics: Animals; Caffeine; Cheek; Cricetinae; Hypotension; Male; Papaverine; Probability

2004
Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery.
    British journal of anaesthesia, 2006, Volume: 97, Issue:6

    Topics: Administration, Topical; Bradycardia; Humans; Hypotension; Intracranial Aneurysm; Intraoperative Com

2006
Hypotension induced changes in cerebral microflow and EEG and their pharmacological alterations.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 678

    Topics: Animals; Blood Pressure; Brain Ischemia; Cats; Cerebrovascular Circulation; Electroencephalography;

1983
Plasma endothelin-1 response to acute hypotension induced by vasodilating agents.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:9

    Topics: Animals; Atrial Natriuretic Factor; Blood Glucose; Blood Pressure; Cyclic GMP; Dogs; Endothelins; Fe

1994
Effect of adenosine triphosphate on human coronary circulation.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:10

    Topics: Adenosine Triphosphate; Blood Flow Velocity; Cardiac Catheterization; Chest Pain; Coronary Angiograp

1998
Mediation of humoral catecholamine secretion by the renin-angiotensin system in hypotensive rainbow trout (Oncorhynchus mykiss).
    The Journal of endocrinology, 1999, Volume: 160, Issue:3

    Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output; Ca

1999
Cardiovascular control via angiotensin II and circulating catecholamines in the spiny dogfish, Squalus acanthias.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1999, Volume: 169, Issue:4-5

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Car

1999
[Effect of hypotension on the arterial system responsiveness].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:11

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Hypotension;

2000
An analysis of the drugs acting on cerebral energy metabolism.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:3

    Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism;

1975
Oligemic-hypotension-induced changes in EEG,CBF and pO2 and their pharmacological modifications.
    Acta neurologica Scandinavica. Supplementum, 1977, Volume: 64

    Topics: Animals; Blood Volume; Cats; Cerebrovascular Circulation; Electroencephalography; Ergolines; Hypoten

1977
Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau.
    The American journal of physiology, 1979, Volume: 237, Issue:2

    Topics: Angiotensinogen; Animals; Female; Fishes; Hematocrit; Hemorrhage; Hypotension; Male; Minoxidil; Papa

1979
Cortical pO2 distribution during oligemic hypotension and its pharmacological modifications.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5

    Topics: Animals; Blood Volume; Cats; Cerebrovascular Circulation; Dihydroergotoxine; Hypotension; Male; Oxyg

1978
Effect of papaverine on cerebral microflow, EEG and pO2 in arterial hypotension.
    Bibliotheca anatomica, 1977, Issue:15 Pt 1

    Topics: Animals; Cats; Cerebrovascular Circulation; Electroencephalography; Hypotension; Microcirculation; O

1977
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
    European journal of clinical investigation, 1971, Volume: 1, Issue:4

    Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc

1971
Clinical studies of induction agents. XL. Althesin with various premedicants.
    British journal of anaesthesia, 1972, Volume: 44, Issue:8

    Topics: Anesthesia, Intravenous; Anesthetics; Atropine; Diazepam; Female; Humans; Hypotension; Ketones; Mepe

1972