papaverine has been researched along with Bewilderment in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the first double-blind study in outpatients to evaluate the effectiveness of dihydrogenated ergot alkaloids (DEA) (Hydergine) versus papaverine in the treatment of selected symptoms associated with mental aging." | 5.04 | Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine). ( Rosen, HJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosen, HJ | 1 |
| Feine-Haake, G | 1 |
| Neiss, A | 1 |
| Weinert, W | 1 |
| Einspruch, BC | 1 |
3 trials available for papaverine and Bewilderment
| Article | Year |
|---|---|
Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine).
Topics: Aged; Aging; Clinical Trials as Topic; Confusion; Dementia; Depression; Dihydroergotoxine; Ergoloid | 1975 |
[The treatment of cerebrovascular insufficiency. Their evaluation in a double-blind study].
Topics: Aged; Aging; Cerebrovascular Disorders; Clinical Trials as Topic; Confusion; Drug Combinations; Drug | 1975 |
Helping to make the final years meaningful for the elderly residents of nursing homes.
Topics: Activities of Daily Living; Aged; Anxiety; Clinical Trials as Topic; Confusion; Depression; Dihydroe | 1976 |