papaverine has been researched along with Autism Spectrum Disorder in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luhach, K | 2 |
| Kulkarni, GT | 2 |
| Singh, VP | 2 |
| Sharma, B | 2 |
2 other studies available for papaverine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Attenuation of neurobehavioural abnormalities by papaverine in prenatal valproic acid rat model of ASD.
Topics: Animals; Anticonvulsants; Autism Spectrum Disorder; Dose-Response Relationship, Drug; Doublecortin P | 2021 |
Effect of papaverine on developmental hyperserotonemia induced autism spectrum disorder related behavioural phenotypes by altering markers of neuronal function, inflammation, and oxidative stress in rats.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Neurons; Oxidative Stress; Papaverine; Phosphod | 2021 |