Page last updated: 2024-11-02

papaverine and Asystole

papaverine has been researched along with Asystole in 6 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death."5.36Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010)
"Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death."1.36Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010)
"Following normothermic cardiac arrest an increase of the coronary resistance and a decrease of the cross section of the coronary arteries have been measured as a function of the duration of the ischaemic period during intermittent coronary perfusion."1.25[Effect of coronary vasodilator agents on the increase of coronary resistance during ischemia]. ( Böttcher, H; Schäfer, W, 1975)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baltaci, B1
Basar, H1
Ozcan, A1
Gulhan, Y1
Aytunur, CS1
Lacroix, P1
Chowdhury, FH1
Haque, MR1
Frierson, JH1
Bigelow, JC1
Duke, DJ1
Mahoney, TM1
Dimas, AP1
Schäfer, W1
Böttcher, H2

Other Studies

6 other studies available for papaverine and Asystole

ArticleYear
Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report.
    Journal of neurosurgery, 2010, Volume: 113, Issue:4

    Topics: Bradycardia; Cisterna Magna; Fatal Outcome; Glasgow Coma Scale; Heart Arrest; Hemodynamics; Humans;

2010
Electrocardiographic toxicity in the guinea pig.
    Current protocols in pharmacology, 2002, Volume: Chapter 5

    Topics: Amitriptyline; Anesthesia; Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Re

2002
Severe hypotension, cardiac arrest, and death after intracisternal instillation of papaverine during anterior communicating artery aneurysm clipping. A case report.
    Acta neurochirurgica, 2013, Volume: 155, Issue:2

    Topics: Fatal Outcome; Female; Heart Arrest; Humans; Hypotension; Instillation, Drug; Intracranial Aneurysm;

2013
Treatment of perioperative mammary artery graft spasm with nifedipine.
    American heart journal, 1993, Volume: 125, Issue:3

    Topics: Aged; Female; Graft Occlusion, Vascular; Heart Arrest; Humans; Internal Mammary-Coronary Artery Anas

1993
[Effect of coronary vasodilator agents on the increase of coronary resistance during ischemia].
    Langenbecks Archiv fur Chirurgie, 1975, Volume: Suppl

    Topics: Animals; Cats; Coronary Circulation; Coronary Disease; Heart Arrest; Ischemia; Nitroglycerin; Papave

1975
Proceedings: The influence of coronary dilators on the ischemic tolerance of the normothermic heart of the cat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Blood Pressure; Cats; Coronary Vessels; Heart; Heart Arrest; Isosorbide Dinitrate; Nitrogly

1974