papaverine has been researched along with Astrocytoma in 6 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, B | 1 |
| Wüllenweber, R | 1 |
| Opler, LA | 1 |
| Makman, MH | 1 |
| Browning, ET | 1 |
| Groppi, VE | 1 |
| Kon, C | 1 |
| Clark, RB | 1 |
| Gross, R | 1 |
| Su, YF | 1 |
| Perkins, JP | 1 |
| Gibson, DA | 1 |
| Reichlin, S | 1 |
| Vernadakis, A | 1 |
1 review available for papaverine and Astrocytoma
| Article | Year |
|---|---|
Differential activation and inhibition of the multiple forms of cyclic nucleotide phosphodiesterase.
Topics: Adenylyl Cyclases; Animals; Astrocytoma; Brain; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoenzyme | 1975 |
5 other studies available for papaverine and Astrocytoma
| Article | Year |
|---|---|
"Intracerebral steal" in man recorded by a heat clearance technique.
Topics: Aminophylline; Animals; Astrocytoma; Blood Pressure; Brain Edema; Brain Injuries; Brain Neoplasms; C | 1968 |
Mediation by cyclic AMP of hormone-stimulated glycogenolysis in cultured rat astrocytoma cells.
Topics: Adenosine Triphosphate; Animals; Astrocytoma; Butyrates; Clone Cells; Cyclic AMP; Drug Antagonism; E | 1972 |
Papaverine, a potent inhibitor of respiration in C-6 astrocytoma cells.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytoma; Cell L | 1974 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocyt | 1974 |
(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.
Topics: Animals; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Line; DNA, Neoplasm; Models, Biological; Ne | 1974 |