papaverine has been researched along with Asthma in 34 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " A comparative study with various drug used in the treatment of asthma (isoprenaline, metaproterenol, salbutamol, clenbuterol, papaverine and atropine) has been conducted." | 7.66 | Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma. ( Di Mezza, F; Giordano, L; Marmo, E; Montanaro, A; Scognamiglio, M, 1981) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 5.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| " Natural products have been a rich source of drug discovery, Theophylline and Methylxanthine originated from tea leaves used for asthma treatment, whereas, Papaverine, a natural isoquinolein originated from Papaver somniferum traditionally used in impotency, altogether as caffeine where firstly described as PDE-inhibiting compounds." | 4.95 | Therapeutic potentials of natural compounds acting on cyclic nucleotide phosphodiesterase families. ( Abusnina, A; Lugnier, C, 2017) |
| " A comparative study with various drug used in the treatment of asthma (isoprenaline, metaproterenol, salbutamol, clenbuterol, papaverine and atropine) has been conducted." | 3.66 | Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma. ( Di Mezza, F; Giordano, L; Marmo, E; Montanaro, A; Scognamiglio, M, 1981) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 1.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (85.29) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abusnina, A | 1 |
| Lugnier, C | 1 |
| Shah, AJ | 1 |
| Gilani, AH | 1 |
| Benyahia, C | 1 |
| Gomez, I | 1 |
| Kanyinda, L | 1 |
| Boukais, K | 1 |
| Danel, C | 1 |
| Leséche, G | 1 |
| Longrois, D | 1 |
| Norel, X | 1 |
| Karasu-Minareci, E | 1 |
| Kaya, Y | 1 |
| Belgin Yildirim, F | 1 |
| PREUNER, R | 1 |
| VON PRITTWITZ, J | 1 |
| GAFFRON, J | 1 |
| BREHMER, W | 1 |
| MARX, W | 1 |
| SCHENK, H | 2 |
| BUHR, G | 2 |
| SUDECK, G | 1 |
| FREISLEBEN, R | 1 |
| GOECHT, R | 1 |
| GUENTHNER, W | 1 |
| JOSEPH, M | 1 |
| KLEINSORGE, H | 1 |
| JAEGER, L | 1 |
| Gurin, NG | 1 |
| Bestry-Fus, I | 1 |
| Di Mezza, F | 1 |
| Giordano, L | 1 |
| Scognamiglio, M | 1 |
| Montanaro, A | 1 |
| Marmo, E | 1 |
| Spyker, D | 1 |
| Love, LA | 1 |
| Brooks, SM | 1 |
| Georg, J | 1 |
| Iwasawa, Y | 1 |
| Kiyomoto, A | 1 |
| Furkert, K | 1 |
| Arsent'ev, FV | 1 |
| Kessler, H | 1 |
| Weiss, S | 1 |
| Scherrer, M | 1 |
| Schwarz, KG | 1 |
| Schwarz, CM | 1 |
| Hammer, O | 1 |
| Mörsdorf, K | 1 |
| Wengenroth, H | 1 |
| Filipowski, P | 1 |
| Somorjai, K | 1 |
| Hahn, F | 1 |
| Teschendorf, HJ | 1 |
| Kretzschmar, R | 1 |
| Gossow, U | 1 |
| Glanzmann, C | 1 |
| Klein, HG | 1 |
| Iven, A | 1 |
| Riethling, AK | 1 |
| Hansen, P | 1 |
| Rulffs, W | 1 |
| Wendt, H | 1 |
2 reviews available for papaverine and Asthma
| Article | Year |
|---|---|
Therapeutic potentials of natural compounds acting on cyclic nucleotide phosphodiesterase families.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Biological Products; Cell Line, Tumor; Cell Pr | 2017 |
[Antiasthmatics. 12].
Topics: Adrenal Cortex Hormones; Aminophylline; Anti-Bacterial Agents; Asthma; Atropine; Barbiturates; Bronc | 1967 |
2 trials available for papaverine and Asthma
| Article | Year |
|---|---|
[Rheohepatographic changes under the effect of clinical trials of drugs in chronic nonspecific lung diseases].
Topics: Aminophylline; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; | 1980 |
[Broncholytic effect of pencardin in chronic bronchial asthma].
Topics: Adult; Aged; Aminophylline; Asthma; Bronchi; Bronchodilator Agents; Clinical Trials as Topic; Drug C | 1981 |
30 other studies available for papaverine and Asthma
| Article | Year |
|---|---|
The calcium channel blocking and phosphodiesterase inhibitory activities of the extract of Andropogon muricatus explains its medicinal use in airways disorders.
Topics: Andropogon; Animals; Asthma; Calcium Channel Blockers; Calcium Channels; Carbachol; Guinea Pigs; In | 2012 |
PGE(2) receptor (EP(4)) agonists: potent dilators of human bronchi and future asthma therapy?
Topics: Acetylcholine; Aged; Animals; Asthma; Bronchi; Bronchodilator Agents; Data Interpretation, Statistic | 2012 |
The achilles heel in melatonin: asthma.
Topics: Acetylcholine; Animals; Asthma; Circadian Rhythm; Dose-Response Relationship, Drug; Injections, Intr | 2012 |
[Experimental studies on therapy of bronchial asthma].
Topics: Asthma; Ephedrine; Humans; Papaverine; Theophylline | 1953 |
[The treatment of bronchial asthma with A-M 1].
Topics: Alkaloids; Asthma; Atropa belladonna; Caffeine; Calcium; Calcium, Dietary; Ephedrine; Humans; Papave | 1953 |
[Parinokhellin in the stenocardiac symptom complex].
Topics: Angina Pectoris; Asthma; Humans; Khellin; Papaverine | 1956 |
[Parinokhellin in the stenocardiac symptom complex].
Topics: Angina Pectoris; Asthma; Humans; Khellin; Papaverine | 1956 |
[Parinokhellin in the stenocardiac symptom complex].
Topics: Angina Pectoris; Asthma; Humans; Khellin; Papaverine | 1956 |
[Parinokhellin in the stenocardiac symptom complex].
Topics: Angina Pectoris; Asthma; Humans; Khellin; Papaverine | 1956 |
[Influenceability of lung ventilation capacity in bronchospastic conditions].
Topics: Asthma; Atropine Derivatives; Bronchitis; Humans; Lung Volume Measurements; Papaverine; Phenobarbita | 1957 |
[Influenceability of lung ventilation capacity in bronchospastic conditions].
Topics: Asthma; Atropine Derivatives; Bronchitis; Humans; Lung Volume Measurements; Papaverine; Phenobarbita | 1957 |
[Influenceability of lung ventilation capacity in bronchospastic conditions].
Topics: Asthma; Atropine Derivatives; Bronchitis; Humans; Lung Volume Measurements; Papaverine; Phenobarbita | 1957 |
[Influenceability of lung ventilation capacity in bronchospastic conditions].
Topics: Asthma; Atropine Derivatives; Bronchitis; Humans; Lung Volume Measurements; Papaverine; Phenobarbita | 1957 |
[Rectal use of the broncholytic kellidrin].
Topics: Administration, Rectal; Asthma; Bronchitis; Diphenhydramine; Emphysema; Ephedrine; Humans; Khellin; | 1957 |
[Asthma-Becker, a new agent for the treatment of bronchospastic states].
Topics: Aminopyrine; Asthma; Ephedrine; Humans; Papaverine; Scopolamine | 1959 |
[Experiences with Makara, a successful antiasthmatic power].
Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Ephedrine; Papaverine; Phenacetin; Theophylline | 1962 |
[SPIROGRAPHIC STUDIES ON ASTHMATIC DYSPNEA].
Topics: Asthma; Atropine; Dyspnea; Humans; Papaverine; Phenobarbital; Spirometry; Theophylline | 1963 |
INTUSSUSCEPTION--AN UNUSUAL COMPLICATION OF ASTHMA.
Topics: Asthma; Atropine; Chlorobutanol; Epinephrine; Intussusception; Jejunum; Papaverine; Pituitary Hormon | 1964 |
[Pharmacological diagnosis in bronchial asthma].
Topics: Acetylcholine; Asthma; Humans; Papaverine; Sympathomimetics | 1961 |
Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma.
Topics: Animals; Asthma; Atropine; Bronchi; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; | 1981 |
An outbreak of pulmonary poisoning.
Topics: Asthma; Consumer Product Safety; Cryptogenic Organizing Pneumonia; Disease Outbreaks; Female; Humans | 1996 |
[Drug treatment of bronchial asthma].
Topics: Adrenal Cortex Hormones; Asthma; Histamine H1 Antagonists; Humans; Nitrites; Papaverine; Parasympath | 1965 |
[Studies on tetrahydroisoquinoline compounds. (3). Pharmacodynamics of 1-(3,4,5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HC1 (AQ-110)].
Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Ethanolamines; Gastrointestinal Motility; Guinea Pi | 1967 |
[The effect of papaverine and arpenal on the pulmonary rheogram in bronchial asthma and chronic non-specific pulmonary diseases].
Topics: Adult; Asthma; Bronchodilator Agents; Chronic Disease; Female; Ganglionic Blockers; Humans; Lung Dis | 1968 |
[Pediatric Asthma-Bisolvon suppositories in the treatment of asthmatic bronchitis and bronchial asthma in childhood].
Topics: Adolescent; Antipyrine; Asthma; Barbiturates; Benzyl Compounds; Bronchitis; Child; Child, Preschool; | 1972 |
[High-dosage intravenous eupaverine-(papaverine-)injection in bronchial asthma].
Topics: Adult; Asthma; Blood Gas Analysis; Blood Pressure; Bronchial Spasm; Electrocardiography; Female; Hem | 1973 |
[Treatment of asthmatic attacks and asthmatic conditions in general practice].
Topics: Adolescent; Adult; Aged; Aminopyrine; Asthma; Child; Drug Combinations; Ephedrine; Family Practice; | 1973 |
[Therapy of asthmatic dyspnea].
Topics: Asthma; Barbiturates; Drug Synergism; Dyspnea; Glucocorticoids; Humans; Papaverine; Theophylline | 1969 |
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity.
Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Ch | 1970 |
[The antiallergic activity of tritoqualine].
Topics: Anaphylaxis; Animals; Asthma; Barium; Benzofurans; Gastric Juice; Guinea Pigs; Heart; Histamine; Ile | 1970 |
[Experiences in the treatment of bronchospastic diseases].
Topics: Adult; Aged; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Diphenhydramine; Ephedrine; | 1967 |
[On drug therapy of emphysema and related diseases in more advanced age].
Topics: Aged; Antipyrine; Asthma; Atropa belladonna; Bronchitis; Bronchodilator Agents; Humans; Papaverine; | 1967 |
[Aerosol therapy of the respiratory tract. Review of the drug assortment of the German Democratic Republic].
Topics: Adrenal Cortex Hormones; Aerosols; Anesthetics, Local; Anti-Bacterial Agents; Antitubercular Agents; | 1968 |
[Factory physician and bronchitis].
Topics: Antipyrine; Asthma; Atropa belladonna; Bronchitis; Humans; Occupational Medicine; Papaverine; Phytot | 1969 |
[Clinical studies on a new antiasthmatic drug (Bronchovydrin dose inhalant)].
Topics: Asthma; Epinephrine; Humans; Papaverine; Respiratory Therapy | 1965 |
[The treatment of bronchial asthma and the combination treatment of acute and chronic bronchial, bronchopulmonary and pulmonary infections with Asthma 23D. An experience report of medical practice during the time period of 5 years].
Topics: Acute Disease; Adult; Aminopyrine; Anti-Bacterial Agents; Antitubercular Agents; Asthma; Atropa bell | 1966 |