papaverine has been researched along with Arteriosclerosis, Coronary in 22 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "FFR measured by postocclusional hyperemia (FFRoccl) caused by balloon occlusion after percutaneous coronary intervention was compared with FFR measured by drug-induced hyperemia (FFR measured by intravenous ATP; and FFR measured by intracoronary papaverine injection [FFRpap]) in 98 lesions from 98 patients." | 3.85 | Postocclusional Hyperemia for Fractional Flow Reserve After Percutaneous Coronary Intervention. ( Hirakawa, A; Hirata, T; Kamiya, H; Kawasaki, M; Kawase, Y; Kikuchi, J; Matsuo, H; Okamoto, S; Okubo, M; Omori, H; Ota, H; Suzuki, T; Tanigaki, T, 2017) |
| "Objective Measuring the fractional flow reserve (FFR) requires the induction of coronary hyperemia, usually with adenosine, adenosine triphosphate (ATP), or papaverine." | 3.85 | Contrast-induced Hyperemia as an Alternative to Drug-induced Hyperemia in the Evaluation of the Fractional Flow Reserve in Coronary Lesions. ( Fujii, Y; Hayashi, Y; Hironobe, N; Kagawa, Y; Kato, Y; Kawase, T; Okimoto, T; Shiode, N; Tamekiyo, H; Ueda, Y; Yamane, K, 2017) |
| "Myocardial ischemia is associated with impaired endothelium-independent vasodilation of resistance coronary arteries and increased minimal coronary resistance." | 1.32 | Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy. ( Fukudome, T; Hamasaki, S; Ishida, S; Kataoka, T; Minagoe, S; Mizoguchi, E; Ninomiya, Y; Okui, H; Otsuji, Y; Saihara, K; Shinsato, T; Tei, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Nakayama, M | 2 |
| Uchiyama, T | 2 |
| Hijikata, N | 1 |
| Kobori, Y | 2 |
| Tanaka, N | 2 |
| Iwasaki, K | 1 |
| Shiode, N | 2 |
| Okimoto, T | 2 |
| Tamekiyo, H | 2 |
| Kawase, T | 2 |
| Yamane, K | 2 |
| Kagawa, Y | 2 |
| Fujii, Y | 2 |
| Ueda, Y | 2 |
| Hironobe, N | 2 |
| Kato, Y | 2 |
| Hayashi, Y | 2 |
| Kawase, Y | 1 |
| Omori, H | 1 |
| Kawasaki, M | 1 |
| Tanigaki, T | 1 |
| Hirata, T | 1 |
| Okamoto, S | 1 |
| Ota, H | 1 |
| Kikuchi, J | 1 |
| Okubo, M | 1 |
| Kamiya, H | 1 |
| Hirakawa, A | 1 |
| Suzuki, T | 1 |
| Matsuo, H | 1 |
| Tanyeli, O | 1 |
| Duman, I | 1 |
| Dereli, Y | 1 |
| Gormus, N | 1 |
| Toy, H | 1 |
| Sahin, AS | 1 |
| Sakoda, K | 1 |
| Hokama, Y | 1 |
| Hoshino, K | 1 |
| Kimura, Y | 1 |
| Ogawa, M | 2 |
| Yamashita, J | 1 |
| Aizawa, Y | 1 |
| Yamashina, A | 1 |
| Shen, LZ | 1 |
| Chen, XJ | 1 |
| Chen, X | 1 |
| Xu, M | 1 |
| Wang, LM | 1 |
| Jiang, YS | 1 |
| BEST, MM | 1 |
| COE, WS | 1 |
| Kataoka, T | 2 |
| Hamasaki, S | 2 |
| Ishida, S | 2 |
| Saihara, K | 2 |
| Okui, H | 2 |
| Fukudome, T | 2 |
| Shinsato, T | 2 |
| Mizoguchi, E | 2 |
| Ninomiya, Y | 2 |
| Otsuji, Y | 1 |
| Minagoe, S | 1 |
| Tei, C | 2 |
| Bahcivan, M | 1 |
| Kolbakir, F | 1 |
| Karamustafa, H | 1 |
| Keceligil, HT | 1 |
| Orihara, K | 1 |
| Oketani, N | 1 |
| Ichiki, T | 1 |
| Kubozono, T | 1 |
| Ichiki, H | 1 |
| Holdright, DR | 1 |
| Clarke, D | 1 |
| Poole-Wilson, PA | 1 |
| Fox, K | 1 |
| Collins, P | 1 |
| Dubois-Randé, JL | 2 |
| Dupouy, P | 2 |
| Aptecar, E | 1 |
| Bhatia, A | 1 |
| Teiger, E | 1 |
| Hittinger, L | 1 |
| Berdeaux, A | 1 |
| Castaigne, A | 1 |
| Geschwind, H | 1 |
| Yamada, H | 1 |
| Azuma, A | 1 |
| Hirasaki, S | 1 |
| Kobara, M | 1 |
| Akagi, A | 1 |
| Shima, T | 1 |
| Miyazaki, H | 1 |
| Sugihara, H | 1 |
| Kohno, Y | 1 |
| Asayama, J | 1 |
| Reddy, KG | 1 |
| Nair, RN | 1 |
| Sheehan, HM | 1 |
| Hodgson, JM | 1 |
| Geschwind, HJ | 1 |
| Pelle, G | 1 |
| Gallot, D | 1 |
| Biraima, AM | 1 |
| Genoni, M | 1 |
| Winkler, MB | 1 |
| Brühlmann, W | 1 |
| Turina, MI | 1 |
| Ten Cate, FJ | 1 |
| Silverman, PR | 1 |
| Sassen, LM | 1 |
| Verdouw, PD | 1 |
| Zeiher, AM | 2 |
| Drexler, H | 2 |
| Wollschläger, H | 2 |
| Just, H | 2 |
| Wilson, RF | 1 |
| Nabel, EG | 1 |
| Selwyn, AP | 1 |
| Ganz, P | 1 |
5 trials available for papaverine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
[Experimental study on the option of antispasmodic drugs for radial artery in elderly patients with coronary atherosclerotic heart disease].
Topics: Aged; Aged, 80 and over; Coronary Artery Bypass; Coronary Artery Disease; Diltiazem; Female; Follow- | 2010 |
Endothoracic papaverine application for internal thoracic artery harvest.
Topics: Aged; Coronary Artery Bypass; Coronary Artery Disease; Drug Administration Routes; Female; Humans; M | 2007 |
Comparison of effect between nitrates and calcium channel antagonist on vascular function in patients with normal or mildly diseased coronary arteries.
Topics: Acetylcholine; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Arter | 2008 |
Comparison of the effects of exercise and cold pressor test on the vasomotor response of normal and atherosclerotic coronary arteries and their relation to the flow-mediated mechanism.
Topics: Adult; Blood Flow Velocity; Cholesterol; Cold Temperature; Coronary Artery Disease; Coronary Vessels | 1995 |
Intracoronary adenosine 5'-triphosphate as an alternative to papaverine for measuring coronary flow reserve.
Topics: Adenosine Triphosphate; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Coronary | 1994 |
17 other studies available for papaverine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Effect of QTU prolongation on hyperemic instantaneous wave-free ratio value: a prospective single-center study.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Blood Flow Velocity; Cardiac Catheterization; Coron | 2020 |
A Comparison between the Instantaneous Wave-free Ratio and Resting Distal Coronary Artery Pressure/Aortic Pressure and the Fractional Flow Reserve: The Diagnostic Accuracy Can Be Improved by the Use of both Indices.
Topics: Aged; Aorta; Arterial Pressure; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Fe | 2017 |
Postocclusional Hyperemia for Fractional Flow Reserve After Percutaneous Coronary Intervention.
Topics: Adenosine Triphosphate; Administration, Intravenous; Aged; Aged, 80 and over; Balloon Occlusion; Car | 2017 |
Relaxation matters: comparison of in-vitro vasodilatory role of botulinum toxin-A and papaverine in human radial artery grafts.
Topics: Adult; Aged; Botulinum Toxins, Type A; Coronary Artery Bypass; Coronary Artery Disease; Female; Huma | 2019 |
Papaverine-induced polymorphic ventricular tachycardia during coronary flow reserve study of patients with moderate coronary artery disease.
Topics: Aged; Coronary Artery Disease; Electrocardiography; Female; Humans; Incidence; Male; Middle Aged; Pa | 2015 |
Contrast-induced Hyperemia as an Alternative to Drug-induced Hyperemia in the Evaluation of the Fractional Flow Reserve in Coronary Lesions.
Topics: Adenosine; Aged; Contrast Media; Coronary Angiography; Coronary Artery Disease; Female; Fractional F | 2017 |
Effects of dioxyline phosphate and enteric-coated khellin on coronary artery insufficiency.
Topics: Coronary Artery Disease; Coronary Vessels; Isoquinolines; Khellin; Papaverine; Phosphates | 1951 |
Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy.
Topics: Acetylcholine; Aged; Blood Flow Velocity; Cardiac Volume; Coronary Angiography; Coronary Artery Dise | 2004 |
Endothelium dependent and independent responses in coronary artery disease measured at angioplasty.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; | 1993 |
Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis.
Topics: Acetylcholine; Adenosine; Blood Flow Velocity; Blood Pressure; Coronary Angiography; Coronary Artery | 1994 |
Assessment of coronary vasomotion by intracoronary ultrasound.
Topics: Aged; Blood Flow Velocity; Case-Control Studies; Cold Temperature; Coronary Artery Disease; Coronary | 1993 |
Mesenteric ischemia after a cardiac operation: arteriosclerotic versus vasospastic etiology.
Topics: Adult; Aged; Cardiopulmonary Bypass; Catheterization; Coronary Artery Disease; Coronary Vasospasm; F | 2002 |
Can myocardial contrast echo determine coronary flow reserve?
Topics: Animals; Blood Pressure; Contrast Media; Coronary Artery Disease; Coronary Circulation; Disease Mode | 1992 |
Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis.
Topics: Acetylcholine; Cold Temperature; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; En | 1991 |
Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.
Topics: Acetylcholine; Cold Temperature; Coronary Angiography; Coronary Artery Disease; Coronary Circulation | 1991 |
Assessment of the human coronary circulation using a Doppler catheter.
Topics: Adenosine; Animals; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Coronary Ves | 1991 |
Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis.
Topics: Acetylcholine; Adult; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary | 1990 |