papaverine has been researched along with Arrhythmia in 29 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Excerpt | Relevance | Reference |
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" Intracoronary papaverine (PAP) is the most potent vasodilator used for the achievement of maximal hyperemia." | 4.02 | Clinical Efficacy of Intracoronary Papaverine After Nicorandil Administration for Safe and Optimal Fractional Flow Reserve Measurement. ( Anai, R; Araki, M; Inoue, K; Kataoka, M; Miura, T; Naka, Y; Okabe, H; Setoyama, K; Sonoda, S, 2021) |
" Intrarenal papaverine neither prolonged the QT interval nor induced ventricular arrhythmias and the safety of which will need to be corroborated in a large study." | 3.76 | Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements. ( Fahsah, I; Jevans, AJ; Kapoor, N; Karim, R; Leesar, MA, 2010) |
"Papaverine, a vasodilator used as a therapeutic agent for a range of diseases, has been reported to increase the risk of occasional serious ventricular arrhythmias." | 3.74 | Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration. ( Choe, H; Hong, HK; Jo, SH; Kim, YJ; Lee, HS; Moh, SH; Park, JC, 2008) |
" All compounds were evaluated for their ability to protect against chloroform-induced ventricular fibrillation in mice." | 3.65 | Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives. ( Neumeyer, JL; Perianayagam, C; Ruchirawat, S, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (86.21) | 18.7374 |
1990's | 1 (3.45) | 18.2507 |
2000's | 1 (3.45) | 29.6817 |
2010's | 1 (3.45) | 24.3611 |
2020's | 1 (3.45) | 2.80 |
Authors | Studies |
---|---|
Neumeyer, JL | 1 |
Perianayagam, C | 1 |
Ruchirawat, S | 1 |
Inoue, K | 1 |
Sonoda, S | 1 |
Naka, Y | 1 |
Okabe, H | 1 |
Setoyama, K | 1 |
Miura, T | 1 |
Anai, R | 1 |
Araki, M | 1 |
Kataoka, M | 1 |
MELVILLE, KI | 2 |
Kim, YJ | 1 |
Hong, HK | 1 |
Lee, HS | 1 |
Moh, SH | 1 |
Park, JC | 1 |
Jo, SH | 1 |
Choe, H | 1 |
Kapoor, N | 1 |
Fahsah, I | 1 |
Karim, R | 1 |
Jevans, AJ | 1 |
Leesar, MA | 1 |
GRUBER, CM | 2 |
LEE, KS | 1 |
SZEKERES, L | 2 |
LENARD, G | 1 |
LINDNER, A | 1 |
SELZER, H | 1 |
CLAASSEN, V | 1 |
GANS, P | 1 |
OFFRINGA, OR | 1 |
ZWAGEMAKERS, JM | 1 |
REISER, I | 1 |
LESLIE, RE | 1 |
DE JONGH, DK | 1 |
VAN PROOSDIJ-HARTZEMA, EG | 1 |
Roche, M | 1 |
Lakermance, B | 1 |
Denavit, M | 1 |
Achard, F | 1 |
Van Haecke, P | 1 |
Lakestani, F | 1 |
Mikaeloff, P | 1 |
Lacroix, P | 1 |
Linée, P | 1 |
Le Pollés, JB | 1 |
Whipple, GH | 1 |
Schroeder, JS | 1 |
Troup, PJ | 1 |
Zipes, DP | 1 |
Kipsidzen, N | 1 |
Kikava, GM | 1 |
Kern, MJ | 1 |
Deligonul, U | 1 |
Serota, H | 1 |
Gudipati, C | 1 |
Buckingham, T | 1 |
Wilson, RF | 1 |
White, CW | 1 |
Fleckenstein, A | 1 |
Grün, G | 1 |
Döring, HJ | 1 |
Haastert, HP | 1 |
Tritthart, H | 1 |
Zoli, I | 1 |
Baroncini, S | 1 |
Cornia, GL | 1 |
Donato, S | 1 |
Minore, G | 1 |
Pigini, G | 1 |
Pretolani, E | 1 |
Papp, G | 1 |
Szmolenszky, T | 1 |
Grodzińska, L | 1 |
Gomensoro, JB | 1 |
Votcal, BE | 1 |
Lozinskij, LG | 1 |
Hanna, C | 1 |
Schmid, JR | 1 |
Haas, H | 2 |
Stafford, A | 1 |
1 review available for papaverine and Arrhythmia
Article | Year |
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Papaverine as an antiarrhythmic agent.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Drug Evaluation, Preclinical | 1977 |
4 trials available for papaverine and Arrhythmia
Article | Year |
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[Study of the effect of ethaverine and papaverine on post-ischemic arrhythmias in the awake dog].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; D | 1977 |
Newer antiarrhythmic agents for patients with coronary artery disease.
Topics: Acebutolol; Adult; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; | 1978 |
[On the efficacy of carbocromen in the treatment of myocardial infarction (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Chromonar; Clinical Trials as To | 1976 |
[Carbochromen in therapy of acute and chronic coronary insufficiency].
Topics: Acute Disease; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease; | 1970 |
24 other studies available for papaverine and Arrhythmia
Article | Year |
---|---|
Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Dogs; Female; Isoquinolines; Mice | 1977 |
Clinical Efficacy of Intracoronary Papaverine After Nicorandil Administration for Safe and Optimal Fractional Flow Reserve Measurement.
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Case-Control Studies; Coronary Angiography; Coronary | 2021 |
The anti-fibrillation action of papaverine and its value in cardiac resuscitation after chloroform-adrenaline ventricular fibrillation in dogs.
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroform; Dogs | 1948 |
The anti-fibrillation action of papaverine and its value in cardiac resuscitation after chloroform-adrenaline ventricular fibrillation.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroform; Epinephrine; | 1948 |
Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.
Topics: Animals; Arrhythmias, Cardiac; Cell Line; Computer Simulation; Cricetinae; Dose-Response Relationshi | 2008 |
Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements.
Topics: Aged; Aorta; Arrhythmias, Cardiac; Biomarkers; Blood Pressure; Blood Pressure Determination; Chi-Squ | 2010 |
Papaverine hydrochloride in thiobarbiturate anesthesia in dogs.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Barbiturates; Dogs; Papaverine; Thiobarbiturates | 1953 |
[Change in the fibrillation threshold of auricular and ventricular musculature of isolated mammalian heart after cooling and after administration of various pharmacological agents].
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Con | 1960 |
PHARMACOLOGICAL PROPERTIES OF MEBEVERINE, A SMOOTH-MUSCLE RELAXANT.
Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Pressure Determination; Cats; Dogs; Esophageal Achalasia | 1963 |
THE ACTION OF PAPAVERINE IN CARDIAC ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Biomedical Research; Drug Therapy; Papaverine; Toxicology | 1964 |
Studies on the action of papaverine and perparine on cardiac fibrillation.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System; | 1952 |
[Experimental study in anesthetized dogs of the harmful effects of coronary microemboli and their prevention by drugs].
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Embolism, Air; Extracorporeal Circulation; Ma | 1983 |
New antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Mexiletine; | 1978 |
Ventricular arrhythmia due to intracoronary papaverine: analysis of QT intervals and coronary vasodilatory reserve.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Flow Velocity; Coronary Vessels; Female; Hemodynamics; Huma | 1990 |
Serious ventricular dysrhythmias after intracoronary papaverine.
Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Vessels; Female; Humans; Injectio | 1988 |
[Ethaverin, a coronary dilator with beta-receptor depressing and antiarrhythmia myocardial effects].
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Epinep | 1973 |
[Therapeutic possibilities in coronary disease].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Arteriosclerosis; Cardiomegaly; Coronary Disease | 1973 |
The effects of quinidine, ajmaline, papaverine and adrenergic beta-receptor inhibitors in experimental BaCl2-arrhythmia developed for the quantitative assay of antiarrhythmic drugs.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Barium; Chlorides; Electrocardiography; Ethanolamines; Fem | 1967 |
The influence of pharmacological blockade of presynaptic and postsynaptic adrenergic structures on electrically induced arrhythmias of the guinea-pig atria.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Depression, Chemical; Guanethidine; Guan | 1969 |
[Use of hydergine in acute ischemic pathology of the brain].
Topics: Acetazolamide; Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Carbon Dioxide; Cerebrovascular Cir | 1967 |
Antiarrhythmic actions of coronary vasodilator agents papaverine, dioxyline and verapamil.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Epinephrine | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
Potentiation of adenosine and the adenine nucleotides by dipyridamole.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Azaguanin | 1966 |