papaverine has been researched along with Arrhythmia in 29 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intracoronary papaverine (PAP) is the most potent vasodilator used for the achievement of maximal hyperemia." | 4.02 | Clinical Efficacy of Intracoronary Papaverine After Nicorandil Administration for Safe and Optimal Fractional Flow Reserve Measurement. ( Anai, R; Araki, M; Inoue, K; Kataoka, M; Miura, T; Naka, Y; Okabe, H; Setoyama, K; Sonoda, S, 2021) |
| " Intrarenal papaverine neither prolonged the QT interval nor induced ventricular arrhythmias and the safety of which will need to be corroborated in a large study." | 3.76 | Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements. ( Fahsah, I; Jevans, AJ; Kapoor, N; Karim, R; Leesar, MA, 2010) |
| "Papaverine, a vasodilator used as a therapeutic agent for a range of diseases, has been reported to increase the risk of occasional serious ventricular arrhythmias." | 3.74 | Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration. ( Choe, H; Hong, HK; Jo, SH; Kim, YJ; Lee, HS; Moh, SH; Park, JC, 2008) |
| " All compounds were evaluated for their ability to protect against chloroform-induced ventricular fibrillation in mice." | 3.65 | Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives. ( Neumeyer, JL; Perianayagam, C; Ruchirawat, S, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (86.21) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Neumeyer, JL | 1 |
| Perianayagam, C | 1 |
| Ruchirawat, S | 1 |
| Inoue, K | 1 |
| Sonoda, S | 1 |
| Naka, Y | 1 |
| Okabe, H | 1 |
| Setoyama, K | 1 |
| Miura, T | 1 |
| Anai, R | 1 |
| Araki, M | 1 |
| Kataoka, M | 1 |
| MELVILLE, KI | 2 |
| Kim, YJ | 1 |
| Hong, HK | 1 |
| Lee, HS | 1 |
| Moh, SH | 1 |
| Park, JC | 1 |
| Jo, SH | 1 |
| Choe, H | 1 |
| Kapoor, N | 1 |
| Fahsah, I | 1 |
| Karim, R | 1 |
| Jevans, AJ | 1 |
| Leesar, MA | 1 |
| GRUBER, CM | 2 |
| LEE, KS | 1 |
| SZEKERES, L | 2 |
| LENARD, G | 1 |
| LINDNER, A | 1 |
| SELZER, H | 1 |
| CLAASSEN, V | 1 |
| GANS, P | 1 |
| OFFRINGA, OR | 1 |
| ZWAGEMAKERS, JM | 1 |
| REISER, I | 1 |
| LESLIE, RE | 1 |
| DE JONGH, DK | 1 |
| VAN PROOSDIJ-HARTZEMA, EG | 1 |
| Roche, M | 1 |
| Lakermance, B | 1 |
| Denavit, M | 1 |
| Achard, F | 1 |
| Van Haecke, P | 1 |
| Lakestani, F | 1 |
| Mikaeloff, P | 1 |
| Lacroix, P | 1 |
| Linée, P | 1 |
| Le Pollés, JB | 1 |
| Whipple, GH | 1 |
| Schroeder, JS | 1 |
| Troup, PJ | 1 |
| Zipes, DP | 1 |
| Kipsidzen, N | 1 |
| Kikava, GM | 1 |
| Kern, MJ | 1 |
| Deligonul, U | 1 |
| Serota, H | 1 |
| Gudipati, C | 1 |
| Buckingham, T | 1 |
| Wilson, RF | 1 |
| White, CW | 1 |
| Fleckenstein, A | 1 |
| Grün, G | 1 |
| Döring, HJ | 1 |
| Haastert, HP | 1 |
| Tritthart, H | 1 |
| Zoli, I | 1 |
| Baroncini, S | 1 |
| Cornia, GL | 1 |
| Donato, S | 1 |
| Minore, G | 1 |
| Pigini, G | 1 |
| Pretolani, E | 1 |
| Papp, G | 1 |
| Szmolenszky, T | 1 |
| Grodzińska, L | 1 |
| Gomensoro, JB | 1 |
| Votcal, BE | 1 |
| Lozinskij, LG | 1 |
| Hanna, C | 1 |
| Schmid, JR | 1 |
| Haas, H | 2 |
| Stafford, A | 1 |
1 review available for papaverine and Arrhythmia
| Article | Year |
|---|---|
Papaverine as an antiarrhythmic agent.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Drug Evaluation, Preclinical | 1977 |
4 trials available for papaverine and Arrhythmia
| Article | Year |
|---|---|
[Study of the effect of ethaverine and papaverine on post-ischemic arrhythmias in the awake dog].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; D | 1977 |
Newer antiarrhythmic agents for patients with coronary artery disease.
Topics: Acebutolol; Adult; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; | 1978 |
[On the efficacy of carbocromen in the treatment of myocardial infarction (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Chromonar; Clinical Trials as To | 1976 |
[Carbochromen in therapy of acute and chronic coronary insufficiency].
Topics: Acute Disease; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease; | 1970 |
24 other studies available for papaverine and Arrhythmia
| Article | Year |
|---|---|
Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Dogs; Female; Isoquinolines; Mice | 1977 |
Clinical Efficacy of Intracoronary Papaverine After Nicorandil Administration for Safe and Optimal Fractional Flow Reserve Measurement.
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Case-Control Studies; Coronary Angiography; Coronary | 2021 |
The anti-fibrillation action of papaverine and its value in cardiac resuscitation after chloroform-adrenaline ventricular fibrillation in dogs.
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroform; Dogs | 1948 |
The anti-fibrillation action of papaverine and its value in cardiac resuscitation after chloroform-adrenaline ventricular fibrillation.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroform; Epinephrine; | 1948 |
Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.
Topics: Animals; Arrhythmias, Cardiac; Cell Line; Computer Simulation; Cricetinae; Dose-Response Relationshi | 2008 |
Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements.
Topics: Aged; Aorta; Arrhythmias, Cardiac; Biomarkers; Blood Pressure; Blood Pressure Determination; Chi-Squ | 2010 |
Papaverine hydrochloride in thiobarbiturate anesthesia in dogs.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Barbiturates; Dogs; Papaverine; Thiobarbiturates | 1953 |
[Change in the fibrillation threshold of auricular and ventricular musculature of isolated mammalian heart after cooling and after administration of various pharmacological agents].
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Con | 1960 |
PHARMACOLOGICAL PROPERTIES OF MEBEVERINE, A SMOOTH-MUSCLE RELAXANT.
Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Pressure Determination; Cats; Dogs; Esophageal Achalasia | 1963 |
THE ACTION OF PAPAVERINE IN CARDIAC ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Biomedical Research; Drug Therapy; Papaverine; Toxicology | 1964 |
Studies on the action of papaverine and perparine on cardiac fibrillation.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System; | 1952 |
[Experimental study in anesthetized dogs of the harmful effects of coronary microemboli and their prevention by drugs].
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Embolism, Air; Extracorporeal Circulation; Ma | 1983 |
New antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Mexiletine; | 1978 |
Ventricular arrhythmia due to intracoronary papaverine: analysis of QT intervals and coronary vasodilatory reserve.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Flow Velocity; Coronary Vessels; Female; Hemodynamics; Huma | 1990 |
Serious ventricular dysrhythmias after intracoronary papaverine.
Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Vessels; Female; Humans; Injectio | 1988 |
[Ethaverin, a coronary dilator with beta-receptor depressing and antiarrhythmia myocardial effects].
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Epinep | 1973 |
[Therapeutic possibilities in coronary disease].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Arteriosclerosis; Cardiomegaly; Coronary Disease | 1973 |
The effects of quinidine, ajmaline, papaverine and adrenergic beta-receptor inhibitors in experimental BaCl2-arrhythmia developed for the quantitative assay of antiarrhythmic drugs.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Barium; Chlorides; Electrocardiography; Ethanolamines; Fem | 1967 |
The influence of pharmacological blockade of presynaptic and postsynaptic adrenergic structures on electrically induced arrhythmias of the guinea-pig atria.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Depression, Chemical; Guanethidine; Guan | 1969 |
[Use of hydergine in acute ischemic pathology of the brain].
Topics: Acetazolamide; Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Carbon Dioxide; Cerebrovascular Cir | 1967 |
Antiarrhythmic actions of coronary vasodilator agents papaverine, dioxyline and verapamil.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Epinephrine | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
Potentiation of adenosine and the adenine nucleotides by dipyridamole.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Azaguanin | 1966 |