papaverine has been researched along with Anxiety in 15 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test whether the loss of PDE10A activity in the striatum was detrimental to normal brain function, we treated wild-type (WT) mice with chronic administration of papaverine, which is a specific inhibitor of PDE10A." | 1.35 | Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice. ( Denovan-Wright, EM; Hebb, AL; Robertson, HA, 2008) |
| "Honeymoon impotence is the inability to perform successful sexual intercourse during the initial experience, especially during the first nights of marriage, and it is relatively frequent in Turkey." | 1.31 | Honeymoon impotence: psychogenic or organic in origin? ( Erdoğru, T; Kadioğlu, A; Köksal, T; Tefekli, A; Usta, MF; Yücel, B, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, N | 1 |
| Dhiman, N | 1 |
| Golani, LK | 1 |
| Sharma, B | 1 |
| Nelson, CJ | 1 |
| Hsiao, W | 1 |
| Balk, E | 1 |
| Narus, J | 1 |
| Tal, R | 1 |
| Bennett, NE | 1 |
| Mulhall, JP | 1 |
| Hebb, AL | 1 |
| Robertson, HA | 1 |
| Denovan-Wright, EM | 1 |
| Johnstone, M | 1 |
| van Deventer, CP | 1 |
| Meuleman, EJ | 1 |
| Bierkens, PB | 1 |
| Sabbe, BG | 1 |
| Smals, AG | 1 |
| Ghanem, H | 1 |
| Sherif, T | 1 |
| Adbel-Gawad, T | 1 |
| Asaad, T | 1 |
| Usta, MF | 1 |
| Erdoğru, T | 1 |
| Tefekli, A | 1 |
| Köksal, T | 1 |
| Yücel, B | 1 |
| Kadioğlu, A | 1 |
| Einspruch, BC | 1 |
| Wassenaar, W | 1 |
| Lancee, WJ | 1 |
| Galloon, S | 1 |
| Gale, GD | 1 |
| Vale, JA | 1 |
| Kirby, RS | 1 |
| Lees, W | 1 |
| Leliefeld, HH | 1 |
| Peulen, GJ | 1 |
| Bähren, W | 1 |
| Scherb, W | 1 |
| Gall, H | 1 |
| Beckert, R | 1 |
| Holzki, G | 1 |
| Stern, FH | 1 |
| De Maio, D | 1 |
| Loan, WB | 1 |
| Dundee, JW | 1 |
| Clarke, RS | 1 |
4 trials available for papaverine and Anxiety
| Article | Year |
|---|---|
The effects of sedation on the digital plethysmogram. A radiotelemetric study of haloperidol.
Topics: Adolescent; Adult; Anxiety; Blood Vessels; Drug Antagonism; Drug Synergism; Female; Fingers; Haloper | 1967 |
Helping to make the final years meaningful for the elderly residents of nursing homes.
Topics: Activities of Daily Living; Aged; Anxiety; Clinical Trials as Topic; Confusion; Depression; Dihydroe | 1976 |
The measurement of anxiety in the pre-surgical patient.
Topics: Anxiety; Female; Humans; Lorazepam; Papaverine; Preanesthetic Medication; Preoperative Care; Psychia | 1977 |
Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride.
Topics: Aged; Anxiety; Clinical Trials as Topic; Dementia; Depression; Humans; Intracranial Arteriosclerosis | 1970 |
11 other studies available for papaverine and Anxiety
| Article | Year |
|---|---|
Papaverine ameliorates prenatal alcohol-induced experimental attention deficit hyperactivity disorder by regulating neuronal function, inflammation, and oxidative stress.
Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Cell Survival; Cy | 2021 |
Injection anxiety and pain in men using intracavernosal injection therapy after radical pelvic surgery.
Topics: Aged; Alprostadil; Anxiety; Drug Combinations; Erectile Dysfunction; Humans; Injections; Male; Middl | 2013 |
Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice.
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Cognition Disorders; C | 2008 |
[Experiences with intracavernous auto-injection for the treatment of erection disorders].
Topics: Adult; Aged; Anxiety; Erectile Dysfunction; Humans; Injections; Interpersonal Relations; Male; Middl | 1993 |
Short term use of intracavernous vasoactive drugs in the treatment of persistent psychogenic erectile dysfunction.
Topics: Adult; Alprostadil; Anxiety; Erectile Dysfunction; Humans; Male; Marriage; Middle Aged; Papaverine; | 1998 |
Honeymoon impotence: psychogenic or organic in origin?
Topics: Adult; Anxiety; Coitus; Diagnosis, Differential; Erectile Dysfunction; Health Knowledge, Attitudes, | 2001 |
Papaverine, benzodiazepines, and prolonged erections.
Topics: Anxiety; Diazepam; Drug Interactions; Humans; Male; Middle Aged; Papaverine; Penile Erection; Priapi | 1991 |
[Psychological factors affect the erectile response to papaverine injection].
Topics: Anxiety; Erectile Dysfunction; Humans; Male; Papaverine; Penile Erection; Priapism | 1991 |
Effects of intracavernosal pharmacotherapy on self-esteem, performance anxiety and partnership in patients with chronic erectile dysfunction.
Topics: Anxiety; Coitus; Drug Combinations; Erectile Dysfunction; Humans; Male; Papaverine; Penile Erection; | 1989 |
[Clinico-theoretical considerations on the association of trifluoperazine and coronary vasoactive drugs in the treatment of anxiety states in aged cardiopathic patients].
Topics: Anxiety; Anxiety Disorders; Heart Diseases; Humans; Papaverine; Pentaerythritol Tetranitrate; Phenot | 1969 |
Studies of drugs given before anaesthesia. XII. A comparison of papaveretum and morphine.
Topics: Adult; Anxiety; Blood Pressure; Drug Synergism; Female; Humans; Morphine; Nausea; Papaverine; Preane | 1966 |