papaverine has been researched along with Anoxia, Brain in 9 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two patients showed signs of elevated intracranial pressure after the procedures and also had ASrO2 readings exceeding 15%; measures to lower arterial hypertension reduced SrO2 in these patients." | 2.72 | [Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty]. ( Carrero, E; Fàbregas, N; Fontanals, J; Rodríguez, L; Salvador, L; Valero, R, 2006) |
| "For aprikalim (n=7), values were as follows: 6+/-2% versus 8+/-2% at 10(-5) mol/L, 22+/-6% versus 15+/-3% at 5 x 10(-5) mol/L, and 41+/-5% versus 32+/-6% at 10(-4) mol/L." | 1.30 | Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets. ( Bari, F; Busija, DW; Domoki, F; Veltkamp, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez, L | 1 |
| Salvador, L | 1 |
| Valero, R | 1 |
| Carrero, E | 1 |
| Fontanals, J | 1 |
| Fàbregas, N | 1 |
| Benzi, G | 1 |
| Gorini, A | 1 |
| Ghigini, B | 1 |
| Arnaboldi, R | 1 |
| Villa, RF | 2 |
| Veltkamp, R | 1 |
| Domoki, F | 1 |
| Bari, F | 1 |
| Busija, DW | 1 |
| Ben-Haim, G | 1 |
| Armstead, WM | 1 |
| Gygax, P | 1 |
| Wiernsperger, N | 1 |
| Meier-Ruge, W | 1 |
| Baumann, T | 1 |
| Strada, P | 1 |
| Marzatico, F | 1 |
| Dagani, F | 1 |
| Goto, K | 1 |
| Suekawa, M | 1 |
| Aburada, M | 1 |
| Hosoya, E | 1 |
| Rosner, I | 1 |
| Legros, J | 1 |
| Berger, C | 1 |
| Heilbrun, MP | 1 |
| Olesen, J | 1 |
1 trial available for papaverine and Anoxia, Brain
| Article | Year |
|---|---|
[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty].
Topics: Aged; Angioplasty, Balloon; Blood Pressure; Brain Ischemia; Carotid Artery, Internal; Carotid Stenos | 2006 |
8 other studies available for papaverine and Anoxia, Brain
| Article | Year |
|---|---|
Modifications by hypoxia and drug treatment of cerebral ATPase plasticity.
Topics: Adenosine Triphosphatases; Almitrine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; C | 1994 |
Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzimidazoles; Calcitonin Gene-Related Peptide; Fe | 1998 |
Stimulus duration-dependent contribution of k(ca) channel activation and cAMP to hypoxic cerebrovasodilation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Blood Gas Analysis; Blood Pressure; | 2000 |
Effect of papaverine and dihydroergotoxine mesylate on cerebral microflow, EEG, and pO2 in oligemic hypotension.
Topics: Animals; Brain; Cats; Cerebral Cortex; Cerebrovascular Circulation; Dihydroergotoxine; Electroenceph | 1978 |
Effect of (-)eburnamonine, papaverine and UDP-glucose on cerebral energy state during and after experimental hypoxia and ischaemia in beagle dog.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Brain Ischem | 1978 |
[Pharmacological study of TJ-8007 (Tsumura-Zokumeito) (I): Protective effects of TJ-8007 against anoxic brain damage].
Topics: Animals; Brain Damage, Chronic; Coma; Drugs, Chinese Herbal; Hypoxia, Brain; Male; Medicine, Chinese | 1987 |
Protective activity of some anti-anginal drugs on asphyxic anoxia of the brain; a contribution to their laboratory evaluation.
Topics: Angina Pectoris; Animals; Asphyxia; Cats; Coronary Circulation; Dipyridamole; Electroencephalography | 1971 |
Regional cerebral blood flow studies in subarachnoid hemorrhage.
Topics: Blood Flow Velocity; Blood Pressure; Cerebral Angiography; Cerebrovascular Circulation; Humans; Hydr | 1972 |