papaverine has been researched along with Anoxemia in 43 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The protective activity of iloprost against hypoxia was studied in isolated rabbit aortic strips precontracted with angiotensin II on the relaxant effect of acetylcholine." | 7.67 | Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia. ( Demirel, E; Türker, RK, 1988) |
| " In 14 other lungs without indomethacin added to the perfusate, we measured Pv20 and Pvo before and during alveolar hypoxia and/or before and after the addition of papaverine to the perfusate." | 3.68 | Micropipette and vascular occlusion pressures in isolated lungs of newborn lambs. ( Fike, CD; Gordon, JB; Kaplowitz, MR, 1993) |
| " Aspirin, indomethacin, and ONO 3708, a PG receptor antagonist, markedly inhibited the hypoxia-induced contraction, whereas superoxide dismutase and OKY 046, a thromboxane (Tx) A2 synthesis inhibitor, were ineffective." | 3.68 | Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. ( Matsumoto, T; Toda, N; Yoshida, K, 1992) |
| " In arteries mounted in vitro for measurements of isometric tension, 20 min of hypoxia (bath oxygen partial pressure, approximately 15 Torr) significantly increased cyclic GMP levels from 16 to 32, from 15 to 25 and from 20 to 38 pmol/g in rabbit common carotid, internal carotid and basilar arteries." | 3.68 | Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit. ( Aubineau, P; Ignarro, L; Lee, J; Pearce, WJ; Reynier-Rebuffel, AM; Seylaz, J, 1990) |
| "The anti-hypoxic effect of cinnarizine was studied using the following experimental methods: hypobaric and anoxic hypoxia in mice, complete ischemia by decapitation in mice and hemic hypoxia in rats." | 3.67 | Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin. ( Milanova, D; Nikolov, R; Nikolova, M, 1984) |
| "The protective activity of iloprost against hypoxia was studied in isolated rabbit aortic strips precontracted with angiotensin II on the relaxant effect of acetylcholine." | 3.67 | Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia. ( Demirel, E; Türker, RK, 1988) |
| "Papaverine was present in two experiments without effect on the CFC data." | 1.27 | Anoxia and capillary filtration coefficient in the isolated cat hindlimb. ( Scott, DR; Watson, PD; Wolf, MB, 1984) |
| "Influence of oxygen deficiency and vasodilating drugs on coronary arterial tonus was investigated." | 1.26 | Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs. ( Honda, F; Kamitani, T; Katsuki, S; Mori, J; Nakano, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (72.09) | 18.7374 |
| 1990's | 10 (23.26) | 18.2507 |
| 2000's | 2 (4.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frydrychowski, AF | 1 |
| Gumiński, W | 1 |
| Rojewski, M | 1 |
| Kaczmarek, J | 1 |
| Juzwa, W | 1 |
| TAYLOR, SH | 1 |
| SCOTT, DB | 1 |
| DONALD, KW | 1 |
| MEYER, JS | 2 |
| ISHIKAWA, S | 1 |
| LEE, TK | 1 |
| GARDINER, AJ | 1 |
| PALMER, KN | 1 |
| ZIELINSKI, J | 1 |
| KOZIOROWSKI, A | 1 |
| Nikolaeva, AG | 1 |
| Girsa, VN | 1 |
| Nemtsov, LM | 1 |
| Nikolov, R | 2 |
| Nikolova, M | 1 |
| Milanova, D | 1 |
| Koburova, K | 1 |
| Phillis, JW | 1 |
| Preston, G | 1 |
| DeLong, RE | 1 |
| Watson, PD | 1 |
| Scott, DR | 1 |
| Wolf, MB | 1 |
| Benzi, G | 5 |
| Arrigoni, E | 1 |
| Pastoris, O | 3 |
| Raimondo, S | 1 |
| Fulle, D | 1 |
| Curti, D | 1 |
| Villa, RF | 3 |
| Dossena, M | 2 |
| Foppa, P | 1 |
| Arnaboldi, R | 2 |
| Gorini, A | 2 |
| Fike, CD | 2 |
| Kaplowitz, MR | 2 |
| Gordon, JB | 1 |
| Koos, BJ | 1 |
| Mason, BA | 1 |
| Ervin, MG | 1 |
| Ghigini, B | 1 |
| Villa, R | 1 |
| Priest, RM | 1 |
| Robertson, TP | 1 |
| Leach, RM | 1 |
| Ward, JP | 1 |
| Ding, ZP | 1 |
| Scheeren, TW | 1 |
| Arndt, JO | 1 |
| Kamitani, T | 1 |
| Nakano, K | 1 |
| Mori, J | 1 |
| Katsuki, S | 1 |
| Honda, F | 1 |
| Bünger, R | 1 |
| Haddy, FJ | 1 |
| Querengässer, A | 1 |
| Gerlach, E | 1 |
| Toda, N | 1 |
| Matsumoto, T | 1 |
| Yoshida, K | 2 |
| Pearce, WJ | 1 |
| Reynier-Rebuffel, AM | 1 |
| Lee, J | 1 |
| Aubineau, P | 1 |
| Ignarro, L | 1 |
| Seylaz, J | 1 |
| Marzatico, F | 1 |
| Dagani, F | 1 |
| Türker, RK | 1 |
| Demirel, E | 1 |
| Kapanci, Y | 1 |
| Assimacopoulos, A | 1 |
| Irle, C | 1 |
| Zwahlen, A | 1 |
| Gabbiani, G | 1 |
| Meisel, M | 1 |
| Meisel, P | 1 |
| Urbaszek, W | 1 |
| Tronicke, E | 1 |
| Modersohn, D | 1 |
| Uhlich, C | 1 |
| Günther, K | 1 |
| Pankau, H | 1 |
| Severin, SE | 1 |
| Minamidate, A | 1 |
| Takano, S | 2 |
| Hashikawa, T | 2 |
| Abiko, Y | 2 |
| Ferrari, M | 1 |
| Boobis, AR | 1 |
| Powis, G | 1 |
| Hayashi, A | 1 |
| Erslev, AJ | 1 |
| Handa, J | 1 |
| Betz, E | 1 |
| Roos, W | 1 |
| Vamosi, B | 1 |
| Kukovetz, WR | 1 |
| Pöch, G | 1 |
| Di Maria, G | 1 |
| Haas, H | 2 |
| Ote, N | 1 |
| Kraupp, O | 1 |
| Mentzel, H | 1 |
2 reviews available for papaverine and Anoxemia
| Article | Year |
|---|---|
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; | 1974 |
Effects of papaverine on smooth muscle and their mechanisms.
Topics: Bucladesine; Calcium; Cell Membrane; Colon; Cyanides; Dinitrophenols; Electrolytes; Electrophysiolog | 1974 |
1 trial available for papaverine and Anoxemia
| Article | Year |
|---|---|
[Vegetotropic therapy and hypobaric hypoxic adaptation in gallbladder motor dysmotility].
Topics: Adaptation, Physiological; Adolescent; Adrenergic beta-Antagonists; Adult; Autonomic Nervous System; | 2007 |
40 other studies available for papaverine and Anoxemia
| Article | Year |
|---|---|
Technical foundations for noninvasive assessment of changes in the width of the subarachnoid space with near-infrared transillumination-backscattering sounding (NIR-TBSS).
Topics: Algorithms; Animals; Cerebrovascular Circulation; Head; Heart Rate; Humans; Hypercapnia; Hypoxia; Li | 2002 |
RESPIRATORY EFFECTS OF GENERAL ANAESTHESIA.
Topics: Anesthesia, General; Atropine; Blood Gas Analysis; Carbon Dioxide; Halothane; Humans; Hypoxia; Oxime | 1964 |
ELECTROMAGNETIC MEASUREMENT OF INTERNAL JUGULAR VENOUS FLOW IN THE MONKEY; EFFECT OF EPILEPSY AND OTHER PROCEDURES.
Topics: Anesthesia; Animals; Apnea; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat | 1964 |
EFFECT OF PREMEDICATION AND GENERAL ANAESTHESIA ON ARTERIAL BLOOD GASES.
Topics: Anesthesia; Anesthesia, General; Atropine; Blood Gas Analysis; Carbon Dioxide; Carotid Arteries; Cer | 1964 |
COMBINED RESPIRATORY AND METABOLIC ACIDOSIS CAUSED BY BRONCHOSPASM IN ANAPHYLACTIC SHOCK.
Topics: Acidosis; Acidosis, Respiratory; Aminopyrine; Anaphylaxis; Bronchial Spasm; Bronchodilator Agents; D | 1964 |
Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin.
Topics: Animals; Atmospheric Pressure; Brain; Cinnarizine; Drug Interactions; Epoprostenol; Hypoxia; Ischemi | 1984 |
Inhibition of phospholipase A2 in vitro by some anti-hypoxic drugs.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; Hypoxia; In Vitro Techniques; Nicergoline; Papaverine; | 1984 |
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
Topics: Adenosine; Animals; Brain; Caffeine; Cerebrovascular Circulation; Dipyridamole; Homeostasis; Hypoxia | 1984 |
Anoxia and capillary filtration coefficient in the isolated cat hindlimb.
Topics: Animals; Capillaries; Cats; Filtration; Hindlimb; Hypoxia; Papaverine; Vascular Resistance | 1984 |
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Animals; Cerebral Cortex; Dogs; Female; Hypoxia; Lactates; Lactic Acid; Oxygen | 1981 |
Modifications by chronic intermittent hypoxia and drug treatment on skeletal muscle metabolism.
Topics: Adenine Nucleotides; Almitrine; Animals; Chronic Disease; Energy Metabolism; Glycogen; Glycolysis; G | 1995 |
Effect of chronic hypoxia on pulmonary vascular pressures in isolated lungs of newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Chronic Disease; Hypoxia; In Vitro Techniques; Lung; Papa | 1994 |
Micropipette and vascular occlusion pressures in isolated lungs of newborn lambs.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Blood Vessels; Hypoxia; In Vitro Tech | 1993 |
Adenosine mediates hypoxic release of arginine vasopressin in fetal sheep.
Topics: Adenosine; Animals; Arginine Vasopressin; Blood Pressure; Fetus; Gases; Heart Rate; Hydrogen-Ion Con | 1994 |
Effect of intermittent mild hypoxia and drug treatment on synaptosomal nonmitochondrial ATPase activities.
Topics: Adenosine Triphosphatases; Animals; Cerebral Cortex; Energy Metabolism; Hypoxia; In Vitro Techniques | 1993 |
Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.
Topics: Animals; Body Weight; Cromakalim; Dinoprost; Dose-Response Relationship, Drug; Heart Ventricles; Hem | 1998 |
Effects of pulmonary blood volume on vascular reactivity in the lung.
Topics: Animals; Atrial Function; Blood Volume; Hypoxia; Lung; Papaverine; Pulmonary Artery; Rabbits; Region | 1999 |
An analysis of the drugs acting on cerebral energy metabolism.
Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism; | 1975 |
Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs.
Topics: Adenosine; Angina Pectoris; Animals; Blood Pressure; Coronary Vessels; Cyanides; Dogs; Hypoxia; In V | 1977 |
An isolated guinea pig heart preparation with in vivo like features.
Topics: Adenine Nucleotides; Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Fema | 1975 |
Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Humans; Hypoxia; | 1992 |
Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit.
Topics: Animals; Cerebrovascular Circulation; Cyclic GMP; Drug Interactions; Hypoxia; Injections, Intravenou | 1990 |
Factors involved in the age-related alteration in the efficiency of the brain bioenergetics.
Topics: Adenine Nucleotides; Aging; Animals; Brain; Electron Transport; Energy Metabolism; gamma-Aminobutyri | 1990 |
Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Epoprostenol; Hypoxia; Iloprost; Muscle Relaxation; M | 1988 |
"Contractile interstitial cells" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies.
Topics: Animals; Cattle; Epinephrine; Fluoresceins; Fluorescent Antibody Technique; Freezing; Goats; Haplorh | 1974 |
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin | 1974 |
[Basic directions in the study of the biochemistry of the myocardium].
Topics: Adaptation, Physiological; Animals; Camphor; Cardiac Glycosides; Cardiomegaly; Cardiovascular Diseas | 1967 |
Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; Myocardium; | 1973 |
The effects of catecholamines upon the metabolism of foreign compounds and upon the distribution of perfusate in the isolated liver of the rat.
Topics: Aniline Compounds; Animals; Bucladesine; Calcium; Catecholamines; Epinephrine; Half-Life; Hexobarbit | 1974 |
Redox state of nicotinamide-adenine dinucleotide in the inner and outer layers of canine left ventricle, and effects of coronary dilators on the redox state.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; NAD; Nitrogl | 1974 |
In vitro production of erythropoietin by kidneys perfused with a serum-free solution.
Topics: Animals; Antibodies; Blood; Culture Media; Erythropoietin; Female; Heparin; Hypoxia; Iron; Iron Radi | 1974 |
Regional pharmacologic responses of the vertebral and internal carotid arteries.
Topics: Acetylcholine; Animals; Bemegride; Blood Flow Velocity; Carbon Dioxide; Carotid Arteries; Epinephrin | 1966 |
[Interactions of cerebrovascular circulation, cerebrospinal fluid and brain volume].
Topics: Absorption; Animals; Blood Pressure Determination; Brain; Carbon Dioxide; Cats; Cerebral Cortex; Cer | 1972 |
Inhibition of hypoxia-induced rise in adenosine release and flow by coronary dilators.
Topics: Adenosine; Animals; Carbon Isotopes; Coronary Circulation; Coronary Vessels; Dipyridamole; Guinea Pi | 1971 |
[Use of radionuclides in the study of the regional distribution of pulmonary perfusion and ventilation].
Topics: Acetylcholine; Age Factors; Ethylenediamines; Humans; Hypertension; Hypoxia; Lung; Lung Compliance; | 1971 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on renal circulation. Renal hemodynamics in hypoxia].
Topics: Animals; Dogs; Female; Hemodynamics; Hypoxia; Kidney; Male; Oxygen; Papaverine; Regional Blood Flow | 1968 |
[Pharmacotherapy of states of deficient myocardial circulation. Pharmacologic aspects].
Topics: Anti-Arrhythmia Agents; Dipyridamole; Humans; Hypoxia; Myocardium; Papaverine; Phenobarbital; Vasodi | 1965 |
[Asphyxia neonatorum. II. Treatment with vasodilator and vagolytic agents].
Topics: Acidosis, Respiratory; Asphyxia Neonatorum; Atropine; Blood Circulation; Humans; Hypercapnia; Hypoxi | 1966 |