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papaverine and Anoxemia

papaverine has been researched along with Anoxemia in 43 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"The protective activity of iloprost against hypoxia was studied in isolated rabbit aortic strips precontracted with angiotensin II on the relaxant effect of acetylcholine."7.67Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia. ( Demirel, E; Türker, RK, 1988)
" In 14 other lungs without indomethacin added to the perfusate, we measured Pv20 and Pvo before and during alveolar hypoxia and/or before and after the addition of papaverine to the perfusate."3.68Micropipette and vascular occlusion pressures in isolated lungs of newborn lambs. ( Fike, CD; Gordon, JB; Kaplowitz, MR, 1993)
" Aspirin, indomethacin, and ONO 3708, a PG receptor antagonist, markedly inhibited the hypoxia-induced contraction, whereas superoxide dismutase and OKY 046, a thromboxane (Tx) A2 synthesis inhibitor, were ineffective."3.68Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. ( Matsumoto, T; Toda, N; Yoshida, K, 1992)
" In arteries mounted in vitro for measurements of isometric tension, 20 min of hypoxia (bath oxygen partial pressure, approximately 15 Torr) significantly increased cyclic GMP levels from 16 to 32, from 15 to 25 and from 20 to 38 pmol/g in rabbit common carotid, internal carotid and basilar arteries."3.68Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit. ( Aubineau, P; Ignarro, L; Lee, J; Pearce, WJ; Reynier-Rebuffel, AM; Seylaz, J, 1990)
"The anti-hypoxic effect of cinnarizine was studied using the following experimental methods: hypobaric and anoxic hypoxia in mice, complete ischemia by decapitation in mice and hemic hypoxia in rats."3.67Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin. ( Milanova, D; Nikolov, R; Nikolova, M, 1984)
"The protective activity of iloprost against hypoxia was studied in isolated rabbit aortic strips precontracted with angiotensin II on the relaxant effect of acetylcholine."3.67Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia. ( Demirel, E; Türker, RK, 1988)
"Papaverine was present in two experiments without effect on the CFC data."1.27Anoxia and capillary filtration coefficient in the isolated cat hindlimb. ( Scott, DR; Watson, PD; Wolf, MB, 1984)
"Influence of oxygen deficiency and vasodilating drugs on coronary arterial tonus was investigated."1.26Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs. ( Honda, F; Kamitani, T; Katsuki, S; Mori, J; Nakano, K, 1977)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199031 (72.09)18.7374
1990's10 (23.26)18.2507
2000's2 (4.65)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frydrychowski, AF1
Gumiński, W1
Rojewski, M1
Kaczmarek, J1
Juzwa, W1
TAYLOR, SH1
SCOTT, DB1
DONALD, KW1
MEYER, JS2
ISHIKAWA, S1
LEE, TK1
GARDINER, AJ1
PALMER, KN1
ZIELINSKI, J1
KOZIOROWSKI, A1
Nikolaeva, AG1
Girsa, VN1
Nemtsov, LM1
Nikolov, R2
Nikolova, M1
Milanova, D1
Koburova, K1
Phillis, JW1
Preston, G1
DeLong, RE1
Watson, PD1
Scott, DR1
Wolf, MB1
Benzi, G5
Arrigoni, E1
Pastoris, O3
Raimondo, S1
Fulle, D1
Curti, D1
Villa, RF3
Dossena, M2
Foppa, P1
Arnaboldi, R2
Gorini, A2
Fike, CD2
Kaplowitz, MR2
Gordon, JB1
Koos, BJ1
Mason, BA1
Ervin, MG1
Ghigini, B1
Villa, R1
Priest, RM1
Robertson, TP1
Leach, RM1
Ward, JP1
Ding, ZP1
Scheeren, TW1
Arndt, JO1
Kamitani, T1
Nakano, K1
Mori, J1
Katsuki, S1
Honda, F1
Bünger, R1
Haddy, FJ1
Querengässer, A1
Gerlach, E1
Toda, N1
Matsumoto, T1
Yoshida, K2
Pearce, WJ1
Reynier-Rebuffel, AM1
Lee, J1
Aubineau, P1
Ignarro, L1
Seylaz, J1
Marzatico, F1
Dagani, F1
Türker, RK1
Demirel, E1
Kapanci, Y1
Assimacopoulos, A1
Irle, C1
Zwahlen, A1
Gabbiani, G1
Meisel, M1
Meisel, P1
Urbaszek, W1
Tronicke, E1
Modersohn, D1
Uhlich, C1
Günther, K1
Pankau, H1
Severin, SE1
Minamidate, A1
Takano, S2
Hashikawa, T2
Abiko, Y2
Ferrari, M1
Boobis, AR1
Powis, G1
Hayashi, A1
Erslev, AJ1
Handa, J1
Betz, E1
Roos, W1
Vamosi, B1
Kukovetz, WR1
Pöch, G1
Di Maria, G1
Haas, H2
Ote, N1
Kraupp, O1
Mentzel, H1

Reviews

2 reviews available for papaverine and Anoxemia

ArticleYear
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
    Die Pharmazie, 1974, Volume: 29, Issue:9

    Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide;

1974
Effects of papaverine on smooth muscle and their mechanisms.
    Pharmacological research communications, 1974, Volume: 6, Issue:2

    Topics: Bucladesine; Calcium; Cell Membrane; Colon; Cyanides; Dinitrophenols; Electrolytes; Electrophysiolog

1974

Trials

1 trial available for papaverine and Anoxemia

ArticleYear
[Vegetotropic therapy and hypobaric hypoxic adaptation in gallbladder motor dysmotility].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2007, Issue:3

    Topics: Adaptation, Physiological; Adolescent; Adrenergic beta-Antagonists; Adult; Autonomic Nervous System;

2007

Other Studies

40 other studies available for papaverine and Anoxemia

ArticleYear
Technical foundations for noninvasive assessment of changes in the width of the subarachnoid space with near-infrared transillumination-backscattering sounding (NIR-TBSS).
    IEEE transactions on bio-medical engineering, 2002, Volume: 49, Issue:8

    Topics: Algorithms; Animals; Cerebrovascular Circulation; Head; Heart Rate; Humans; Hypercapnia; Hypoxia; Li

2002
RESPIRATORY EFFECTS OF GENERAL ANAESTHESIA.
    Lancet (London, England), 1964, Apr-18, Volume: 1, Issue:7338

    Topics: Anesthesia, General; Atropine; Blood Gas Analysis; Carbon Dioxide; Halothane; Humans; Hypoxia; Oxime

1964
ELECTROMAGNETIC MEASUREMENT OF INTERNAL JUGULAR VENOUS FLOW IN THE MONKEY; EFFECT OF EPILEPSY AND OTHER PROCEDURES.
    Journal of neurosurgery, 1964, Volume: 21

    Topics: Anesthesia; Animals; Apnea; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

1964
EFFECT OF PREMEDICATION AND GENERAL ANAESTHESIA ON ARTERIAL BLOOD GASES.
    British medical journal, 1964, Dec-05, Volume: 2, Issue:5422

    Topics: Anesthesia; Anesthesia, General; Atropine; Blood Gas Analysis; Carbon Dioxide; Carotid Arteries; Cer

1964
COMBINED RESPIRATORY AND METABOLIC ACIDOSIS CAUSED BY BRONCHOSPASM IN ANAPHYLACTIC SHOCK.
    Medicina thoracalis, 1964, Volume: 21

    Topics: Acidosis; Acidosis, Respiratory; Aminopyrine; Anaphylaxis; Bronchial Spasm; Bronchodilator Agents; D

1964
Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:3

    Topics: Animals; Atmospheric Pressure; Brain; Cinnarizine; Drug Interactions; Epoprostenol; Hypoxia; Ischemi

1984
Inhibition of phospholipase A2 in vitro by some anti-hypoxic drugs.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:8

    Topics: Arachidonic Acid; Arachidonic Acids; Humans; Hypoxia; In Vitro Techniques; Nicergoline; Papaverine;

1984
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1984, Volume: 4, Issue:4

    Topics: Adenosine; Animals; Brain; Caffeine; Cerebrovascular Circulation; Dipyridamole; Homeostasis; Hypoxia

1984
Anoxia and capillary filtration coefficient in the isolated cat hindlimb.
    The American journal of physiology, 1984, Volume: 246, Issue:2 Pt 2

    Topics: Animals; Capillaries; Cats; Filtration; Hindlimb; Hypoxia; Papaverine; Vascular Resistance

1984
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
    European neurology, 1981, Volume: 20, Issue:3

    Topics: Adenine Nucleotides; Animals; Cerebral Cortex; Dogs; Female; Hypoxia; Lactates; Lactic Acid; Oxygen

1981
Modifications by chronic intermittent hypoxia and drug treatment on skeletal muscle metabolism.
    Neurochemical research, 1995, Volume: 20, Issue:2

    Topics: Adenine Nucleotides; Almitrine; Animals; Chronic Disease; Energy Metabolism; Glycogen; Glycolysis; G

1995
Effect of chronic hypoxia on pulmonary vascular pressures in isolated lungs of newborn pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:6

    Topics: Animals; Animals, Newborn; Blood Pressure; Chronic Disease; Hypoxia; In Vitro Techniques; Lung; Papa

1994
Micropipette and vascular occlusion pressures in isolated lungs of newborn lambs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:4

    Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Blood Vessels; Hypoxia; In Vitro Tech

1993
Adenosine mediates hypoxic release of arginine vasopressin in fetal sheep.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 2

    Topics: Adenosine; Animals; Arginine Vasopressin; Blood Pressure; Fetus; Gases; Heart Rate; Hydrogen-Ion Con

1994
Effect of intermittent mild hypoxia and drug treatment on synaptosomal nonmitochondrial ATPase activities.
    Journal of neuroscience research, 1993, Apr-15, Volume: 34, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Cerebral Cortex; Energy Metabolism; Hypoxia; In Vitro Techniques

1993
Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Body Weight; Cromakalim; Dinoprost; Dose-Response Relationship, Drug; Heart Ventricles; Hem

1998
Effects of pulmonary blood volume on vascular reactivity in the lung.
    Intensive care medicine, 1999, Volume: 25, Issue:12

    Topics: Animals; Atrial Function; Blood Volume; Hypoxia; Lung; Papaverine; Pulmonary Artery; Rabbits; Region

1999
An analysis of the drugs acting on cerebral energy metabolism.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:3

    Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism;

1975
Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:2

    Topics: Adenosine; Angina Pectoris; Animals; Blood Pressure; Coronary Vessels; Cyanides; Dogs; Hypoxia; In V

1977
An isolated guinea pig heart preparation with in vivo like features.
    Pflugers Archiv : European journal of physiology, 1975, Volume: 353, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Fema

1975
Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 2

    Topics: Animals; Aspirin; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Humans; Hypoxia;

1992
Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: Animals; Cerebrovascular Circulation; Cyclic GMP; Drug Interactions; Hypoxia; Injections, Intravenou

1990
Factors involved in the age-related alteration in the efficiency of the brain bioenergetics.
    Mechanisms of ageing and development, 1990, Volume: 56, Issue:2

    Topics: Adenine Nucleotides; Aging; Animals; Brain; Electron Transport; Energy Metabolism; gamma-Aminobutyri

1990
Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia.
    Pharmacology, 1988, Volume: 36, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Epoprostenol; Hypoxia; Iloprost; Muscle Relaxation; M

1988
"Contractile interstitial cells" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies.
    The Journal of cell biology, 1974, Volume: 60, Issue:2

    Topics: Animals; Cattle; Epinephrine; Fluoresceins; Fluorescent Antibody Technique; Freezing; Goats; Haplorh

1974
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Jul-01, Volume: 29, Issue:13

    Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin

1974
[Basic directions in the study of the biochemistry of the myocardium].
    Kardiologiia, 1967, Volume: 7, Issue:11

    Topics: Adaptation, Physiological; Animals; Camphor; Cardiac Glycosides; Cardiomegaly; Cardiovascular Diseas

1967
Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:1

    Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; Myocardium;

1973
The effects of catecholamines upon the metabolism of foreign compounds and upon the distribution of perfusate in the isolated liver of the rat.
    Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24

    Topics: Aniline Compounds; Animals; Bucladesine; Calcium; Catecholamines; Epinephrine; Half-Life; Hexobarbit

1974
Redox state of nicotinamide-adenine dinucleotide in the inner and outer layers of canine left ventricle, and effects of coronary dilators on the redox state.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; NAD; Nitrogl

1974
In vitro production of erythropoietin by kidneys perfused with a serum-free solution.
    Blood, 1974, Volume: 44, Issue:1

    Topics: Animals; Antibodies; Blood; Culture Media; Erythropoietin; Female; Heparin; Hypoxia; Iron; Iron Radi

1974
Regional pharmacologic responses of the vertebral and internal carotid arteries.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 152, Issue:2

    Topics: Acetylcholine; Animals; Bemegride; Blood Flow Velocity; Carbon Dioxide; Carotid Arteries; Epinephrin

1966
[Interactions of cerebrovascular circulation, cerebrospinal fluid and brain volume].
    Die Medizinische Welt, 1972, Apr-15, Volume: 23, Issue:16

    Topics: Absorption; Animals; Blood Pressure Determination; Brain; Carbon Dioxide; Cats; Cerebral Cortex; Cer

1972
Inhibition of hypoxia-induced rise in adenosine release and flow by coronary dilators.
    Cardiology, 1971, Volume: 56, Issue:1

    Topics: Adenosine; Animals; Carbon Isotopes; Coronary Circulation; Coronary Vessels; Dipyridamole; Guinea Pi

1971
[Use of radionuclides in the study of the regional distribution of pulmonary perfusion and ventilation].
    Recenti progressi in medicina, 1971, Volume: 50, Issue:2

    Topics: Acetylcholine; Age Factors; Ethylenediamines; Humans; Hypertension; Hypoxia; Lung; Lung Compliance;

1971
[Studies on coronary-active substances].
    Arzneimittel-Forschung, 1970, Volume: 20

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per

1970
[Studies on coronary-active substances].
    Arzneimittel-Forschung, 1970, Volume: 20

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per

1970
[Studies on renal circulation. Renal hemodynamics in hypoxia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1968, Feb-10, Volume: 57, Issue:1

    Topics: Animals; Dogs; Female; Hemodynamics; Hypoxia; Kidney; Male; Oxygen; Papaverine; Regional Blood Flow

1968
[Pharmacotherapy of states of deficient myocardial circulation. Pharmacologic aspects].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1965, Volume: 46, Issue:10

    Topics: Anti-Arrhythmia Agents; Dipyridamole; Humans; Hypoxia; Myocardium; Papaverine; Phenobarbital; Vasodi

1965
[Asphyxia neonatorum. II. Treatment with vasodilator and vagolytic agents].
    Zeitschrift fur Kinderheilkunde, 1966, Volume: 96, Issue:2

    Topics: Acidosis, Respiratory; Asphyxia Neonatorum; Atropine; Blood Circulation; Humans; Hypercapnia; Hypoxi

1966