papaverine has been researched along with Aneurysm, Ruptured in 20 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the techniques and efficacy of intracranial intraarterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage caused by aneurysm rupture." | 7.69 | Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage. ( Aldrich, EF; Clouston, JE; Numaguchi, Y; Simard, JM; Zitnay, KM; Zoarski, GH, 1995) |
| "We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine." | 7.69 | Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage. ( Nakamura, S; Watanabe, H; Yoshida, K, 1997) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 7.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "Improvement in cerebral oxygenation as well as prevention of cerebral lactic acidosis can be successfully achieved after intraarterial infusion of papaverine." | 3.70 | Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm. ( Fandino, J; Kaku, Y; Schuknecht, B; Valavanis, A; Yonekawa, Y, 1998) |
| "To evaluate the techniques and efficacy of intracranial intraarterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage caused by aneurysm rupture." | 3.69 | Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage. ( Aldrich, EF; Clouston, JE; Numaguchi, Y; Simard, JM; Zitnay, KM; Zoarski, GH, 1995) |
| "We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine." | 3.69 | Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage. ( Nakamura, S; Watanabe, H; Yoshida, K, 1997) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 3.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "Treatment of acute aneurysmal subarachnoid hemorrhages consists of occluding the aneurysm to prevent rebleed, attempting to prevent vasospasm, and maintaining blood flow to the brain through vessels in vasospasm." | 2.43 | Endovascular management of a patient after SAH. ( Chang, S; Murphy, K; Srinivas, A, 2005) |
| "Symptomatic cerebral vasospasm is also a strong predictor of poor clinical outcome and has thus drawn a great deal of interest from cerebrovascular surgeons." | 2.43 | Endovascular treatment strategies for cerebral vasospasm. ( Batjer, HH; Bendok, BR; Miller, JW; Mindea, SA; Yang, BP, 2006) |
| "The best strategy for treatment of subarachnoid hemorrhage due to ruptured cerebral aneurysm is obliteration of the aneurysm as soon as possible." | 1.32 | Combined endovascular treatment for both intracranial aneurysm and symptomatic vasospasm. ( Duckwiler, GR; Gobin, YP; Martin, NA; Murayama, Y; Patel, AB; Song, JK; Tateshima, S; Uda, K; Viñuela, F, 2003) |
| "Patients who developed cerebral vasospasm and underwent cerebral arteriographic, transcranial Doppler ultrasonographic, and cerebral blood flow (CBF) studies before and after endovascular therapy for cerebral arterial spasm (vasospasm) were included in this study." | 1.31 | Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial doppler ultrasonographic velocities, and cerebral artery diameters. ( Afari, A; Glenn, TC; Gonzalez, NR; Guthrie, D; Lee, JH; Martin, NA; Oskouian, RJ; Viñuela, F, 2002) |
| "Ninety nine patients with ruptured cerebral aneurysms, who survived more than one week and were treated in Wakayama City in 1994, were studied." | 1.30 | The effect of endovascular therapy for cerebral arterial spasm, its limitation and pitfalls. ( Hyotani, G; Itakura, T; Kido, T; Kinoshita, Y; Kuriyama, T; Naka, Y; Nakai, K; Terada, T; Tsuura, M; Yokote, H, 1997) |
| "It is difficult to treat ruptured aneurysms with symptomatic vasospasm." | 1.30 | [Endovascular surgery for untreated ruptured aneurysm with symptomatic vasospasm]. ( Akiyama, Y; Hayashi, N; Higashi, T; Kikuchi, H; Kokuzawa, J; Manaka, H; Morizane, A; Nagata, I; Nakahara, I; Namura, S; Nishizaki, J; Sakai, H; Sakai, N; Takahashi, J; Yanamoto, H, 1999) |
| "The study focused on patients with aneurysmal subarachnoid hemorrhage who developed clinical signs and symptoms of vasospasm, which was documented by cerebral angiography." | 1.29 | Intracranial pressure changes induced during papaverine infusion for treatment of vasospasm. ( Eskridge, JM; Grady, MS; McAuliffe, W; Newell, DW; Townsend, M; Winn, HR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (55.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JH | 1 |
| Yi, HJ | 1 |
| Ko, Y | 1 |
| Kim, YS | 1 |
| Kim, DW | 1 |
| Kim, JM | 1 |
| Menon, G | 1 |
| Baldawa, SS | 1 |
| Nair, S | 1 |
| Fandino, J | 2 |
| Taussky, P | 1 |
| Marbacher, S | 1 |
| Muroi, C | 1 |
| Diepers, M | 1 |
| Fathi, AR | 1 |
| Remonda, L | 1 |
| Oskouian, RJ | 1 |
| Martin, NA | 2 |
| Lee, JH | 1 |
| Glenn, TC | 1 |
| Guthrie, D | 1 |
| Gonzalez, NR | 1 |
| Afari, A | 1 |
| Viñuela, F | 2 |
| Murayama, Y | 1 |
| Song, JK | 1 |
| Uda, K | 1 |
| Gobin, YP | 1 |
| Duckwiler, GR | 1 |
| Tateshima, S | 1 |
| Patel, AB | 1 |
| Chang, S | 1 |
| Srinivas, A | 1 |
| Murphy, K | 1 |
| Mindea, SA | 1 |
| Yang, BP | 1 |
| Bendok, BR | 1 |
| Miller, JW | 1 |
| Batjer, HH | 2 |
| Elsayed, AA | 1 |
| Moran, CJ | 1 |
| Cross, DT | 1 |
| Derdeyn, CP | 1 |
| Pilgram, TK | 1 |
| Milburn, JM | 1 |
| Dacey, RG | 1 |
| Diringer, MN | 1 |
| McAuliffe, W | 1 |
| Townsend, M | 1 |
| Eskridge, JM | 2 |
| Newell, DW | 2 |
| Grady, MS | 1 |
| Winn, HR | 2 |
| Giller, CA | 1 |
| Purdy, P | 1 |
| Giller, A | 1 |
| Kopitnik, T | 1 |
| Clouston, JE | 1 |
| Numaguchi, Y | 1 |
| Zoarski, GH | 1 |
| Aldrich, EF | 1 |
| Simard, JM | 1 |
| Zitnay, KM | 1 |
| Yoshimura, S | 1 |
| Tsukahara, T | 2 |
| Hashimoto, N | 1 |
| Kazekawa, K | 2 |
| Kobayashi, A | 1 |
| Yoshida, K | 1 |
| Watanabe, H | 1 |
| Nakamura, S | 1 |
| Terada, T | 1 |
| Kinoshita, Y | 1 |
| Yokote, H | 1 |
| Tsuura, M | 1 |
| Nakai, K | 1 |
| Itakura, T | 1 |
| Hyotani, G | 1 |
| Kuriyama, T | 1 |
| Naka, Y | 1 |
| Kido, T | 1 |
| Kaku, Y | 2 |
| Schuknecht, B | 1 |
| Valavanis, A | 1 |
| Yonekawa, Y | 2 |
| Morizane, A | 1 |
| Nakahara, I | 1 |
| Sakai, N | 1 |
| Yanamoto, H | 1 |
| Akiyama, Y | 1 |
| Sakai, H | 1 |
| Higashi, T | 1 |
| Namura, S | 1 |
| Takahashi, J | 1 |
| Nishizaki, J | 1 |
| Kokuzawa, J | 1 |
| Manaka, H | 1 |
| Hayashi, N | 1 |
| Nagata, I | 1 |
| Kikuchi, H | 1 |
| Elliott, JP | 1 |
| Wanke, I | 1 |
| Dörfler, A | 1 |
| Dietrich, U | 1 |
| Aalders, T | 1 |
| Forsting, M | 1 |
| Kassell, NF | 1 |
| Helm, G | 1 |
| Simmons, N | 1 |
| Phillips, CD | 1 |
| Cail, WS | 1 |
3 reviews available for papaverine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Endovascular management of a patient after SAH.
Topics: Aneurysm, Ruptured; Aortic Dissection; Cerebral Hemorrhage; Clinical Trials as Topic; Embolization, | 2005 |
Endovascular treatment strategies for cerebral vasospasm.
Topics: Aneurysm, Ruptured; Angioplasty, Balloon; Humans; Papaverine; Subarachnoid Hemorrhage; Time Factors; | 2006 |
Endovascular therapy for aneurysmal vasospasm.
Topics: Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Cerebral Angiography; Cerebrovascular | 1999 |
2 trials available for papaverine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Effectiveness of papaverine cisternal irrigation for cerebral vasospasm after aneurysmal subarachnoid hemorrhage and measurement of biomarkers.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Biomarkers; Cell Adhesion Molecule-1; Cell Adhes | 2014 |
Effect of intraarterial papaverine and/or angioplasty on the cerebral veins in patients with vasospasm after subarachnoid hemorrhage due to ruptured intracranial aneurysms.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty; Cerebral Angiography; Cerebral Vein | 2006 |
15 other studies available for papaverine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Transient oculomotor nerve palsy after topical administration of intracisternal papaverine.
Topics: Administration, Topical; Aneurysm, Ruptured; Cisterna Magna; Dose-Response Relationship, Drug; Human | 2011 |
The concept of a hybrid operating room: applications in cerebrovascular surgery.
Topics: Aneurysm, Ruptured; Angiography, Digital Subtraction; Angioplasty; Arteriovenous Malformations; Endo | 2013 |
Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial doppler ultrasonographic velocities, and cerebral artery diameters.
Topics: Adult; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Brain; Cerebral Angiography; C | 2002 |
Combined endovascular treatment for both intracranial aneurysm and symptomatic vasospasm.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty, Balloon; Cerebral Angiography; Comb | 2003 |
Intracranial pressure changes induced during papaverine infusion for treatment of vasospasm.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Pressure; Female; Glasgow Coma Scale; H | 1995 |
Elevated transcranial Doppler ultrasound velocities following therapeutic arterial dilation.
Topics: Adult; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Carotid Artery Diseases; Cereb | 1995 |
Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Basilar Artery; Blindness; Carotid Artery, Internal; Cerebral Angio | 1995 |
Intra-arterial infusion of papaverine combined with intravenous administration of high-dose nicardipine for cerebral vasospasm.
Topics: Adult; Aged; Aneurysm, Ruptured; Calcium Channel Blockers; Cerebral Angiography; Dose-Response Relat | 1995 |
Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage.
Topics: Adult; Amrinone; Aneurysm, Ruptured; Brain; Cerebral Angiography; Female; Humans; Image Processing, | 1997 |
The effect of endovascular therapy for cerebral arterial spasm, its limitation and pitfalls.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Cerebral Angiography; Disability Evaluation; | 1997 |
Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm.
Topics: Acidosis, Lactic; Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Pressure; Blood Volum | 1998 |
[Endovascular surgery for untreated ruptured aneurysm with symptomatic vasospasm].
Topics: Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Embolization, Therapeutic; Female; Humans; Intracran | 1999 |
Combined endovascular therapy of ruptured aneurysms and cerebral vasospasm.
Topics: Adult; Aneurysm, Ruptured; Carotid Arteries; Cerebral Angiography; Combined Modality Therapy; Emboli | 2000 |
Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty, Balloon; Female; Humans; Infusions, | 1992 |
Treatment of cerebral vasospasm with intra-arterial papaverine.
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; I | 1992 |