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papaverine and Anesthesia

papaverine has been researched along with Anesthesia in 39 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Adult ewes were studied to determine the effects of barbiturate anesthesia on renal function and the natriuretic response to renal vasodilation by papaverine and acetylcholine."7.66Renal function during consciousness and anesthesia in sheep: effects of renal vasodilation by papaverine and acetylcholine. ( Blaine, EH; Dunlay, MC, 1981)
"Fifty male patients undergoing elective surgery for duodenal ulcer received either phenoperidine or halothane 0."5.04Influence of anaesthetic technique on postoperative pain. A comparison of anaesthetic supplementation with halothane and with phenoperidine. ( Henderson, JJ; Parbrook, GD, 1976)
" Furthermore, KB-944 is well absorbed from the intestinal tract, and produces a long-acting increase in the coronary blood flow."1.26Vasodilator action of KB-944, a new calcium antagonist. ( Ito, K; Kanazawa, T; Morita, T; Nose, T; Yoshino, K, 1982)
" CV-705 was well absorbed through the digestive tract."1.26[Vasodilator action of (+/-)-1-(3, 4, 5-trimethoxybenzyl)-6-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride (CV-705) in anesthetized dogs (author's transl)]. ( Ikezawa, K; Kiyomoto, A; Nagao, T; Nakajima, H; Sato, M, 1977)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199030 (76.92)18.7374
1990's6 (15.38)18.2507
2000's3 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lacroix, P2
Roffey, P1
Thangathurai, D1
Mikhail, M1
Mogos, M1
Riad, M1
Stein, J1
SCHMIDT, L1
GRUBER, CM2
LEE, KS1
RIEGER, H1
DELPHAUT, J2
LANZA, M2
SARLES, H2
DARBY, TD1
SPROUSE, JH1
WALTON, RP1
BAYER, R1
BERGMANN, H1
DUNDEE, JW2
ARMSTRONG, CA1
ALEXANDER, JP1
HARGROVE, RL1
PEARCE, DJ1
MEYER, JS1
ISHIKAWA, S1
LEE, TK1
GARDINER, AJ1
PALMER, KN1
QUEVAUVILLER, A1
GARCET, S1
Just-Viera, JO1
Yeager, GH1
Kramer, WG1
Romagnoli, A1
Morita, T1
Yoshino, K1
Kanazawa, T1
Ito, K1
Nose, T1
Blaine, EH2
Dunlay, MC1
Kifor, I1
Williams, GH1
Vickers, MA1
Sullivan, MP1
Jodbert, P1
Dluhy, RG1
Aikawa, N1
Ohmori, K1
Vemulapalli, R1
Kurowski, S1
Salisbury, B1
Parker, E1
Davis, H1
Linée, P1
Laville, MP1
Le Pollès, JB1
Ikezawa, K1
Nagao, T1
Sato, M1
Nakajima, H1
Kiyomoto, A1
Henderson, JJ1
Parbrook, GD1
Kirby, MJ1
Leighton, M1
Turner, P1
Haruno, A1
Dormehl, IC1
De Bruin, D1
Jacobs, L1
Maree, M1
Du Plessis, DJ1
Bugge, JF1
Stokke, ES1
Kiil, F1
Archie, JP1
Sakanashi, M1
Noguchi, K1
Kato, T1
Matsuzaki, T1
Kinjo, N1
Ikema, S1
Miyagi, H1
Moromizato, H1
Nakasone, J1
Kinjo, Y1
Gristwood, RW1
Comer, MB1
Eden, RJ1
Taylor, EM1
Turner, JA1
Wallduck, M1
Owen, DA1
Kato, H1
Suzuki, S1
Nakao, K1
Lee, EB1
Takagi, K1
Loh, L1
LeDouarec, JC1
Duhault, J1
Laubie, M1
Walton, CA1
Bovill, JG1
Clarke, RS1
Pandit, SK1
Moore, J1
Baskett, PJ1
Armstrong, R1
Dey, PK1
Mukherjee, A1

Trials

2 trials available for papaverine and Anesthesia

ArticleYear
Influence of anaesthetic technique on postoperative pain. A comparison of anaesthetic supplementation with halothane and with phenoperidine.
    British journal of anaesthesia, 1976, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Duo

1976
The cardiovascular effects of pancuronium bromide.
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Analgesics; Androstanes; Anesthesia; Bis-Trimethylammonium Compounds; Blood Pressure; Bromides; Hear

1970

Other Studies

37 other studies available for papaverine and Anesthesia

ArticleYear
Electrocardiographic toxicity in the guinea pig.
    Current protocols in pharmacology, 2002, Volume: Chapter 5

    Topics: Amitriptyline; Anesthesia; Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Re

2002
Anesthesiologist's role in bowel relaxation for artificial bladder construction.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:6

    Topics: Anesthesia; Cystectomy; Digestive System Physiological Phenomena; Humans; Ileum; Muscle Relaxation;

2003
[Influence of different anesthetics on respiratory effects of papaverine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1952, Volume: 216, Issue:1-2

    Topics: Anesthesia; Anesthetics; Cell Respiration; Humans; Leadership; Papaverine; Respiration

1952
Papaverine hydrochloride in thiobarbiturate anesthesia in dogs.
    Archives internationales de pharmacodynamie et de therapie, 1953, Volume: 93, Issue:2

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Barbiturates; Dogs; Papaverine; Thiobarbiturates

1953
[Safe mitigation of labor pain by belladonna-exclud suppository].
    Die Medizinische, 1955, Aug-20, Issue:33-34

    Topics: Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Atropa belladonna; Barbiturates; Femal

1955
[Effect of morphine, papaverine, theophylline and khellin on biliary manometric tests in the dog under chloralose sedation].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7

    Topics: Anesthesia; Animals; Biliary Tract; Chloralose; Dogs; Humans; Khellin; Manometry; Morphine; Papaveri

1956
[Effect of morphine, papaverine, theophylline and khellin on biliary manometric tests in the dog under chloralose sedation].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7

    Topics: Anesthesia; Animals; Biliary Tract; Chloralose; Dogs; Humans; Khellin; Manometry; Morphine; Papaveri

1956
[Effect of morphine, papaverine, theophylline and khellin on biliary manometric tests in the dog under chloralose sedation].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7

    Topics: Anesthesia; Animals; Biliary Tract; Chloralose; Dogs; Humans; Khellin; Manometry; Morphine; Papaveri

1956
[Effect of morphine, papaverine, theophylline and khellin on biliary manometric tests in the dog under chloralose sedation].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7

    Topics: Anesthesia; Animals; Biliary Tract; Chloralose; Dogs; Humans; Khellin; Manometry; Morphine; Papaveri

1956
Evaluation of sympathetic reflex effects on the inotropic action of nitroglycerin, quinidine, papaverine, aminophylline and isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 1958, Volume: 122, Issue:3

    Topics: Aminophylline; Anesthesia; Anesthesia, Conduction; Humans; Isoproterenol; Nitroglycerin; Papaverine;

1958
[Testing labor-accelerating substances with an index of effectiveness].
    Medizinische Klinik, 1963, Jul-05, Volume: 58

    Topics: Anesthesia; Anesthesia, Obstetrical; Atropa belladonna; Female; Humans; Labor, Obstetric; Oxytocics;

1963
[SENSITIVITY CHANGES OF THE ISOLATED GUINEA PIG INTESTINE BY PREMEDICATION, ANESTHESIA AND SPASMOLYTICS].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1963, Volume: 18

    Topics: Aminopyrine; Anesthesia; Animals; Atropine; Barium; Bis-Trimethylammonium Compounds; Chlorides; Chlo

1963
CLINICAL STUDIES OF INDUCTION AGENTS. VIII. A COMPARISON OF THE EFFECTS OF ATROPINE AND HYOSCINE ON THE COURSE AND SEQUELAE OF THIOPENTONE ANAESTHESIA.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Anesthesia; Anesthesiology; Atropine; Biomedical Research; Humans; Injections, Intramuscular; Meperi

1964
AN ANAESTHETIC TECHNIQUE FOR BRONCHOSCOPY.
    Anaesthesia, 1964, Volume: 19

    Topics: Anesthesia; Anesthesia, General; Anesthesiology; Anesthetics; Atropine; Bronchoscopy; Geriatrics; Hu

1964
ELECTROMAGNETIC MEASUREMENT OF INTERNAL JUGULAR VENOUS FLOW IN THE MONKEY; EFFECT OF EPILEPSY AND OTHER PROCEDURES.
    Journal of neurosurgery, 1964, Volume: 21

    Topics: Anesthesia; Animals; Apnea; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

1964
EFFECT OF PREMEDICATION AND GENERAL ANAESTHESIA ON ARTERIAL BLOOD GASES.
    British medical journal, 1964, Dec-05, Volume: 2, Issue:5422

    Topics: Anesthesia; Anesthesia, General; Atropine; Blood Gas Analysis; Carbon Dioxide; Carotid Arteries; Cer

1964
[Power of local anesthesia of certain dihydrogen and bromine derivatives of papaverine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1950, Volume: 144, Issue:3-4

    Topics: Anesthesia; Anesthesia, Local; Anesthesiology; Bromine; Papaverine

1950
Pulmonary embolism in unanesthetized dogs.
    Surgery, gynecology & obstetrics, 1967, Volume: 125, Issue:1

    Topics: Anesthesia; Animals; Atropine; Barium Sulfate; Blood Gas Analysis; Blood Pressure; Dogs; Electrocard

1967
Papaverine disposition in cardiac surgery patients and the effect of cardiopulmonary bypass.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:2

    Topics: Adult; Aged; Anesthesia; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Half-Life; Hum

1984
Vasodilator action of KB-944, a new calcium antagonist.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Anesthesia; Animals; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Coronary Circulation;

1982
Renal function during consciousness and anesthesia in sheep: effects of renal vasodilation by papaverine and acetylcholine.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:2

    Topics: Acetylcholine; Anesthesia; Animals; Blood Pressure; Consciousness; Female; Glomerular Filtration Rat

1981
Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum.
    The Journal of urology, 1997, Volume: 157, Issue:5

    Topics: Alprostadil; Anesthesia; Angiotensin II; Animals; Dogs; Humans; Injections; Losartan; Male; Papaveri

1997
Effect of zaldaride maleate, an antidiarrheal compound, on visceral pain reflex induced by small intestinal distention in anesthetized rats.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:4

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Animals, Newborn; Antidiarrheals; Atropine; Benzi

1999
Activation of central melanocortin receptors by MT-II increases cavernosal pressure in rabbits by the neuronal release of NO.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: alpha-MSH; Alprostadil; Anesthesia; Animals; Blood Pressure; Culture Techniques; Cyclic GMP; Dose-Re

2001
[Effect of L-eburnamonine on bronchial respiratory resistance in the anesthetized guinea pig. Comparison with vincamine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1978, Volume: 172, Issue:6

    Topics: Airway Resistance; Anesthesia; Animals; Atropine; Brompheniramine; Bronchi; Bronchial Spasm; Female;

1978
[Vasodilator action of (+/-)-1-(3, 4, 5-trimethoxybenzyl)-6-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride (CV-705) in anesthetized dogs (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:7

    Topics: Anesthesia; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Central Venous

1977
Sodium excretion after renal vasodilation by papaverine in conscious and anesthetized sheep.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2

    Topics: Anesthesia; Animals; Female; Glomerular Filtration Rate; Infusions, Intra-Arterial; Kidney; Male; Na

1978
The influence of premedication, anaesthesia, age and weight on glucose uptake into human isolated skeletal muscle.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:2

    Topics: Adult; Age Factors; Aged; Anesthesia; Atropine; Body Weight; Female; Glucose; Glycogen; Humans; Male

1976
Effects of propiverine hydrochloride on the spontaneous contractions of isolated guinea-pig urinary bladder strip and rhythmic urinary bladder contractions of anesthetized dog.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:12

    Topics: Anesthesia; Animals; Benzilates; Blood Pressure; Dogs; Female; Flavoxate; Guinea Pigs; Heart Rate; I

1992
Quantitative evaluation of the penile vascular status by means of the 99mTc-penogram in conjunction with either papaverine or prostaglandin E1 in the anaesthetised baboon model.
    European urology, 1991, Volume: 20, Issue:1

    Topics: Alprostadil; Anesthesia; Animals; Male; Papaverine; Papio; Penis; Radionuclide Imaging; Regional Blo

1991
Effects of bradykinin and papaverine on renal autoregulation and renin release in the anaesthetized dog.
    Acta physiologica Scandinavica, 1991, Volume: 143, Issue:4

    Topics: Anesthesia; Animals; Blood Pressure; Bradykinin; Dogs; Female; Glomerular Filtration Rate; Kidney; M

1991
Some determinants of papaverine-induced femoral artery pressure gradients.
    The Journal of surgical research, 1990, Volume: 48, Issue:3

    Topics: Anesthesia; Blood Pressure; Femoral Artery; Humans; Mathematics; Models, Cardiovascular; Papaverine;

1990
Investigation on the effect of dipyridamole and papaverine on regional blood flow and cardiac hemodynamics in anesthetized dogs.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:9

    Topics: Anesthesia; Animals; Coronary Circulation; Dipyridamole; Dogs; Female; Injections, Intravenous; Male

1989
In vivo pharmacological studies with SK&F 94836, a potent inotrope/vasodilator with a sustained duration of action.
    British journal of pharmacology, 1988, Volume: 93, Issue:4

    Topics: Anesthesia; Animals; Cardiotonic Agents; Cats; Dogs; Female; Guanidines; Heart Rate; Hemodynamics; I

1988
Vasodilating effect of crude platycodin in anesthetized dogs.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:5

    Topics: Anesthesia; Animals; Atropine; Coronary Circulation; Diphenhydramine; Dogs; Drug Evaluation, Preclin

1973
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron

1969
Clinical pharmacy symposium. Clinical pharmacology and clinical pharmacy: a necessary alliance for practical advances in rational drug therapy.
    Journal of clinical pharmacology, 1974, Volume: 14, Issue:1

    Topics: Aminophylline; Anesthesia; Angina Pectoris; Drug Therapy; Education, Pharmacy; Humans; Oxygen Inhala

1974
Clinical studies of induction agents. 38. Effect of premedicants and supplements on ketamine anaesthesia.
    British journal of anaesthesia, 1971, Volume: 43, Issue:6

    Topics: Adult; Analgesics; Anesthesia; Atropine; Benperidol; Blood Pressure; Cyclohexanes; Diazepam; Dreams;

1971
Anaesthetic problems in multiple sclerosis. Are certain agents contraindicated?
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Adult; Amobarbital; Anesthesia; Anesthetics; Atropine; Female; Halothane; Humans; Levallorphan; Mepe

1970
Responses of the circulatory system towards the vasoactive drugs in hypothermia under different anesthesia.
    Die Naturwissenschaften, 1967, Volume: 54, Issue:9

    Topics: Acetylcholine; Anesthesia; Animals; Blood Circulation; Cats; Epinephrine; Ergonovine; Heart; Histami

1967