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papaverine and Alkalosis

papaverine has been researched along with Alkalosis in 5 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Alkalosis: A pathological condition that removes acid or adds base to the body fluids.

Research Excerpts

ExcerptRelevanceReference
"This study tested whether hypocapnic constriction of the rabbit basilar artery in vitro can be triggered by a nitric oxide (NO) synthase inhibitor, and whether the resulting constriction is (1) due to the alkaline pH associated with hypocapnia, and (2) endothelin-1 mediated."7.70Hypocapnic constriction in rabbit basilar artery in vitro: triggering by N(G)-monomethyl-L-arginine monoacetate and dependence on endothelin-1 and alkalosis. ( Lee, BH; Rapoport, RM; Zuccarello, M, 2000)
"This study tested whether hypocapnic constriction of the rabbit basilar artery in vitro can be triggered by a nitric oxide (NO) synthase inhibitor, and whether the resulting constriction is (1) due to the alkaline pH associated with hypocapnia, and (2) endothelin-1 mediated."3.70Hypocapnic constriction in rabbit basilar artery in vitro: triggering by N(G)-monomethyl-L-arginine monoacetate and dependence on endothelin-1 and alkalosis. ( Lee, BH; Rapoport, RM; Zuccarello, M, 2000)
"Hypocapnia/alkalosis is a consequence of several lung and metabolic pathologies."1.35[Effect of hypocapnia/alkalosis on the fluid filtration rate in isolated and perfused rabbit lungs]. ( Caraballo, JC; Castro, I; Gutiérrez, J; Pezzulo, A; Sánchez-de León, R; Trejo, H; Urich, D, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Urich, D1
Trejo, H1
Pezzulo, A1
Caraballo, JC1
Gutiérrez, J1
Castro, I1
Sánchez-de León, R1
Zuccarello, M1
Lee, BH1
Rapoport, RM1
Montastruc, JL1
Cotonat, J1
Andrieu, M1
Shinoara, Y1
Baïsset, A1
Montastruc, P1
Tran, MA1

Other Studies

5 other studies available for papaverine and Alkalosis

ArticleYear
[Effect of hypocapnia/alkalosis on the fluid filtration rate in isolated and perfused rabbit lungs].
    Investigacion clinica, 2008, Volume: 49, Issue:2

    Topics: Adrenergic beta-Agonists; Alkalosis; Animals; Anti-Inflammatory Agents; Blood Pressure; Fenoterol; F

2008
Hypocapnic constriction in rabbit basilar artery in vitro: triggering by N(G)-monomethyl-L-arginine monoacetate and dependence on endothelin-1 and alkalosis.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Acetylcholine; Alkalies; Alkalosis; Animals; Basilar Artery; Carbon Dioxide; Dose-Response Relations

2000
Effect of variations of blood pH on the haemodynamic actions of papaverine.
    Archivos de farmacologia y toxicologia, 1978, Volume: 4, Issue:1

    Topics: Acidosis; Alkalosis; Animals; Blood Physiological Phenomena; Cardiac Output; Dogs; Female; Heart Rat

1978
Mechanism of chemical control of cerebral vasomotor activity.
    Neurology, 1973, Volume: 23, Issue:2

    Topics: Acetazolamide; Alkalosis; Animals; Blood Pressure; Carbon Dioxide; Cats; Cerebrovascular Circulation

1973
[Experimental study of the influence of blood pH variations on the bronchial effects of various drugs].
    Pathologie-biologie, 1971, Volume: 19, Issue:23

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Aminophylline; Anim

1971