papaverine has been researched along with Alcohol Drinking in 16 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tetrahydropapaveroline (THP) was infused ICV for up to 14 days either chronically around the clock or acutely once per day in doses previously found to induce an abnormally high intake of alcohol." | 5.26 | Naloxone alters alcohol drinking induced in the rat by tetrahydropapaveroline (THP) infused ICV. ( Critcher, EC; Myers, RD, 1982) |
| "Tetrahydropapaveroline (THP) was infused ICV for up to 14 days either chronically around the clock or acutely once per day in doses previously found to induce an abnormally high intake of alcohol." | 1.26 | Naloxone alters alcohol drinking induced in the rat by tetrahydropapaveroline (THP) infused ICV. ( Critcher, EC; Myers, RD, 1982) |
| " The current report provides a replicatin of the original experiments and also an extension of the work to complete dose-response curves for salsolinol and THP." | 1.26 | A critical evaluation of tetrahydroisoquinoline induced ethanol preference in rats. ( Deitrich, RA; Duncan, C, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCoy, JG | 1 |
| Strawbridge, C | 1 |
| McMurtrey, KD | 1 |
| Kane, VB | 1 |
| Ward, CP | 1 |
| Myers, RD | 9 |
| Critcher, EC | 1 |
| Vasileva, T | 1 |
| Clow, A | 1 |
| Stolerman, IP | 1 |
| Murray, RM | 1 |
| Sandler, M | 1 |
| Sinclair, JD | 1 |
| McCaleb, ML | 1 |
| Ruwe, WD | 1 |
| Duncan, C | 1 |
| Deitrich, RA | 1 |
| Utkan, T | 1 |
| Erden, F | 1 |
| Yildiz, F | 1 |
| Ozdemirci, S | 1 |
| Ulak, G | 1 |
| Gacar, MN | 1 |
| Melchior, CL | 2 |
| Hoch, DB | 1 |
| Messiha, FS | 1 |
| Privette, TH | 2 |
| Oster, L | 1 |
| Martinez, TT | 1 |
16 other studies available for papaverine and Alcohol Drinking
| Article | Year |
|---|---|
A re-evaluation of the role of tetrahydropapaveroline in ethanol consumption in rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Dr | 2003 |
Naloxone alters alcohol drinking induced in the rat by tetrahydropapaveroline (THP) infused ICV.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Eating; Male; Naloxone; Papav | 1982 |
The effect of brain hemodynamics exerted by papaverine hydrochloride in conjunction with smoking and alcohol consumption.
Topics: Adult; Aged; Alcohol Drinking; Cerebrovascular Circulation; Cerebrovascular Disorders; Humans; Middl | 1981 |
Ethanol preference in rats: increased consumption after intraventricular administration of tetrahydropapaveroline.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Food Preferences; Injections, | 1983 |
Cerebroventricular tetrahydropapaveroline infusions and ethanol consumption in the rat.
Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Animals; Behavior, Animal; Carbolines; Humans; Inject | 1982 |
Alcohol drinking induced in the monkey by tetrahydropapaveroline (THP) infused into the cerebral ventricle.
Topics: Alcohol Drinking; Animals; Choice Behavior; Dose-Response Relationship, Drug; Female; Injections, In | 1982 |
A critical evaluation of tetrahydroisoquinoline induced ethanol preference in rats.
Topics: Alcohol Drinking; Animals; Catheters, Indwelling; Cerebral Ventricles; Dopamine; Dose-Response Relat | 1980 |
Chronic ethanol consumption impairs adrenoceptor- and purinoceptor-mediated relaxations of isolated rat detrusor smooth muscle.
Topics: Adenosine; Alcohol Drinking; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanol; Isoprote | 2001 |
Tetrahydroisoquinolines in the brain: the basis of an animal model of alcoholism.
Topics: Alcohol Drinking; Alcoholism; Alkaloids; Animals; Brain; Carbolines; Disease Models, Animal; Humans; | 1978 |
Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain.
Topics: Alcohol Drinking; Animals; Biogenic Amines; Brain Chemistry; Dose-Response Relationship, Drug; Human | 1977 |
Preference for alcohol evoked by tetrahydropapaveroline (THP) chronically infused in the cerebral ventricle of the rat.
Topics: Alcohol Drinking; Animals; Choice Behavior; Dose-Response Relationship, Drug; Drinking Behavior; Eth | 1977 |
Localization of sites in the brain mediating alcohol drinking induced by tetrahydropapaveroline (THP).
Topics: Alcohol Drinking; Animals; Appetitive Behavior; Brain; Brain Mapping; Gyrus Cinguli; Hippocampus; Pa | 1979 |
Papaverine, tetrahydropapaverine and ethanol metabolizing enzymes.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Ethanol; Isoquinolines; Li | 1990 |
A neuroanatomical substrate for alcohol drinking: identification of tetrahydropapaveroline (THP)-reactive sites in the rat brain.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Limbic System; Male; Papaverine; Rats; | 1989 |
Anatomical mapping of tetrahydropapaveroline-reactive sites in brain mediating suppression of alcohol drinking in the rat.
Topics: Alcohol Drinking; Animals; Brain; Brain Mapping; Dose-Response Relationship, Drug; Male; Papaverine; | 1989 |
The effect of tetrahydropapaveroline and naltrexone on voluntary ethanol ingestion in rats.
Topics: Alcohol Drinking; Animals; Drug Interactions; Naltrexone; Papaverine; Rats; Rats, Inbred Strains; Re | 1988 |