papaverine has been researched along with Acute Pain in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.
| Excerpt | Relevance | Reference |
|---|---|---|
| " papaverine hydrochloride plus a diclofenac suppository were more effective than the diclofenac suppository alone for treating acute renal colic." | 9.16 | Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study. ( Asgari, SA; Asli, MM; Aval, HB; Enshaei, A; Esmaeili, S; Farzan, A; Ghanaei, MM; Madani, AH; Maghsoudi, PA; Shakiba, M, 2012) |
| " papaverine hydrochloride plus a diclofenac suppository were more effective than the diclofenac suppository alone for treating acute renal colic." | 5.16 | Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study. ( Asgari, SA; Asli, MM; Aval, HB; Enshaei, A; Esmaeili, S; Farzan, A; Ghanaei, MM; Madani, AH; Maghsoudi, PA; Shakiba, M, 2012) |
| " This was performed by comparison of mean pain intensity difference, total pain relief at 2 h, onset of pain relief, decrease in number of pain episodes, global improvement, and adverse effects." | 2.87 | Efficacy and safety of fixed-dose combination of drotaverine hydrochloride (80 mg) and paracetamol (500 mg) in amelioration of abdominal pain in acute infectious gastroenteritis: A randomized controlled trial. ( Koli, J; Narang, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Narang, S | 1 |
| Koli, J | 1 |
| Asgari, SA | 1 |
| Asli, MM | 1 |
| Madani, AH | 1 |
| Maghsoudi, PA | 1 |
| Ghanaei, MM | 1 |
| Shakiba, M | 1 |
| Aval, HB | 1 |
| Enshaei, A | 1 |
| Farzan, A | 1 |
| Esmaeili, S | 1 |
2 trials available for papaverine and Acute Pain
| Article | Year |
|---|---|
Efficacy and safety of fixed-dose combination of drotaverine hydrochloride (80 mg) and paracetamol (500 mg) in amelioration of abdominal pain in acute infectious gastroenteritis: A randomized controlled trial.
Topics: Abdominal Pain; Acetaminophen; Acute Pain; Administration, Oral; Adolescent; Adult; Analgesics; Doub | 2018 |
Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study.
Topics: Acute Disease; Acute Pain; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; D | 2012 |