papaverine has been researched along with Acute Brain Injuries in 12 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstead, WM | 1 |
| Kiessling, JW | 1 |
| Riley, J | 1 |
| Cines, DB | 1 |
| Higazi, AA | 1 |
| Zhang, F | 1 |
| Sprague, SM | 1 |
| Farrokhi, F | 1 |
| Henry, MN | 1 |
| Son, MG | 1 |
| Vollmer, DG | 1 |
| SOMMER, H | 1 |
| FISCHER, EK | 1 |
| VERBEEK, CA | 1 |
| Vardiman, AB | 1 |
| Kopitnik, TA | 1 |
| Purdy, PD | 1 |
| Batjer, HH | 1 |
| Samson, DS | 1 |
| Kongstad, L | 1 |
| Grände, PO | 1 |
| Wüllenweber, R | 1 |
| Heiss, WD | 1 |
| Prosenz, P | 1 |
| Bruck, J | 1 |
| Borzeix, MG | 1 |
| Labos, M | 1 |
| Cahn, J | 1 |
| von Albert, HH | 1 |
| Marguth, F | 1 |
| Langanke, D | 1 |
| Keller, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non Invasive and Non-Contact Dual-modal Imaging Of Tissue Oxygenation and Vascular Reactivity Dynamic Imaging Of Tissue Metabolism and Vascular Function.[NCT01573390] | 0 participants (Actual) | Observational | Withdrawn (stopped due to most of the study team left the institution prior to study initiation) | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for papaverine and Acute Brain Injuries
| Article | Year |
|---|---|
Effect of proxazole on total and regional cerebral blood flow.
Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Brain Injuries; Brain Neoplasms; Cerebrovascular Cir | 1973 |
11 other studies available for papaverine and Acute Brain Injuries
| Article | Year |
|---|---|
tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Topics: Animals; Animals, Newborn; Anthracenes; Brain Injuries; Butadienes; Drug Interactions; Female; Imida | 2011 |
Reversal of attenuation of cerebrovascular reactivity to hypercapnia by a nitric oxide donor after controlled cortical impact in a rat model of traumatic brain injury.
Topics: Animals; Blood Pressure; Brain Injuries; Carbon Dioxide; Cerebrovascular Circulation; Cortical Sprea | 2002 |
[Studies on the use of a combined papaverine-quinine medication].
Topics: Brain; Brain Injuries; Humans; Meniere Disease; Papaverine; Quinine | 1958 |
[Causes and nyxanthan therapy of cerebral decompensation in brain injuries].
Topics: Barbiturates; Brain; Brain Injuries; Humans; Papaverine; Theophylline | 1958 |
[Personal experiences with the use of monotrean in the treatment of brain concussion and its sequelae].
Topics: Brain Concussion; Brain Injuries; Papaverine; Quinine | 1950 |
Treatment of traumatic arterial vasospasm with intraarterial papaverine infusion.
Topics: Brain; Brain Injuries; Carotid Artery, Internal; Cerebral Angiography; Humans; Infusions, Intra-Arte | 1995 |
The role of arterial and venous pressure for volume regulation of an organ enclosed in a rigid compartment with application to the injured brain.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Capillaries; Cats; Cerebrospinal Fluid Pressure; Cer | 1999 |
"Intracerebral steal" in man recorded by a heat clearance technique.
Topics: Aminophylline; Animals; Astrocytoma; Blood Pressure; Brain Edema; Brain Injuries; Brain Neoplasms; C | 1968 |
[Experimental model of brain edema for the study of drugs acting on blood flow and-or brain metabolism].
Topics: Animals; Arachnoid; Biological Assay; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cere | 1972 |
[Therapy of headaches, including migraine].
Topics: Analgesics; Brain Injuries; Brain Neoplasms; Drug Synergism; Ergoloid Mesylates; Eye Diseases; Heada | 1969 |
[Effect of papaquine on the course of labor and puerperium in comparison with dolcontral and spasmonal].
Topics: Analgesics; Brain Injuries; Dystocia; Female; Humans; Infant Mortality; Infant, Newborn; Obstetric L | 1965 |