papaverine has been researched along with Acoustic Neuroma in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some evidence in the literature supports the topical application of papaverine to the cochlear nerve to prevent internal auditory artery vasospasm and cochlear ischemia as a method of enhancing the ability to preserve hearing during acoustic neuroma surgery." | 3.74 | Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report. ( Liu, JK; MacDonald, JD; Sayama, CM; Shelton, C, 2007) |
| "A case of loss of spontaneous and evoked facial muscle activity, and transient postoperative facial paralysis, after topical application of papaverine in the CPA during surgery for an acoustic neuroma using intraoperative cranial nerve monitoring is reported." | 3.70 | Topical papaverine and facial nerve dysfunction in cerebellopontine angle surgery. ( Digoy, GP; Eisenman, DJ; Selesnick, SH; Victor, JD, 1999) |
| "Papaverine use was not associated with increased rates of perioperative complications (P = 0." | 1.72 | Safety and Facial Nerve Outcomes of Intracisternal Papaverine Irrigation for Vestibular Schwannoma Resection. ( Angeli, SI; Brown, CS; Chang, H; Dinh, CT; Eshraghi, AA; Khan, NR; Morcos, JJ; Shah, AH; Silva, MA; Telischi, FF, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, MA | 1 |
| Chang, H | 1 |
| Shah, AH | 1 |
| Khan, NR | 1 |
| Brown, CS | 1 |
| Dinh, CT | 1 |
| Eshraghi, AA | 1 |
| Telischi, FF | 1 |
| Angeli, SI | 1 |
| Morcos, JJ | 1 |
| Mastronardi, L | 1 |
| Campione, A | 1 |
| Liu, JK | 1 |
| Sayama, CM | 1 |
| Shelton, C | 1 |
| MacDonald, JD | 1 |
| Eisenman, DJ | 1 |
| Digoy, GP | 1 |
| Victor, JD | 1 |
| Selesnick, SH | 1 |
1 review available for papaverine and Acoustic Neuroma
| Article | Year |
|---|---|
Diluted intracisternal papaverine for microvascular protection of cranial nerves during vestibular schwannoma and cerebello-pontine angle surgery. Commentary and review of the literature.
Topics: Brain Stem Neoplasms; Cerebellopontine Angle; Cranial Nerves; Hearing Loss; Humans; Neuroma, Acousti | 2023 |
3 other studies available for papaverine and Acoustic Neuroma
| Article | Year |
|---|---|
Safety and Facial Nerve Outcomes of Intracisternal Papaverine Irrigation for Vestibular Schwannoma Resection.
Topics: Facial Nerve; Facial Nerve Injuries; Humans; Neuroma, Acoustic; Papaverine; Postoperative Complicati | 2022 |
Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report.
Topics: Administration, Topical; Facial Paralysis; Female; Humans; Intraoperative Complications; Middle Aged | 2007 |
Topical papaverine and facial nerve dysfunction in cerebellopontine angle surgery.
Topics: Action Potentials; Administration, Topical; Adult; Animals; Arteries; Cerebellopontine Angle; Cerebe | 1999 |