papaverine has been researched along with Abdominal Cramps in 11 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine hydrochloride was as effective as sodium diclofenac in alleviating pain and the combined treatment group showed a slight trend of more rapid relief." | 2.73 | Papaverine hydrochloride for the treatment of renal colic: an old drug revisited. A prospective, randomized study. ( Lifshitz, DA; Livne, PM; Margel, D; Moskovitz, B; Nativ, O; Sandovski, U; Snir, N; Sulkes, J, 2008) |
| "Drotaverine was effective in 79% of patients and placebo in only 46% (P < 0." | 2.71 | The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones. ( Blaskó, G; Jelakovic, B; Köszegi, G; Molnár, DL; Mrklic, B; Romics, I; Timberg, G, 2003) |
| "Cholelithiasis was proven by ultrasonography." | 2.66 | Biliary colic treatment and acute cholecystitis prevention by prostaglandin inhibitor. ( Alon, R; Goldman, G; Kahn, PJ; Wiznitzer, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yencilek, F | 1 |
| Aktas, C | 1 |
| Goktas, C | 1 |
| Yilmaz, C | 1 |
| Yilmaz, U | 1 |
| Sarica, K | 1 |
| Garmish, OS | 1 |
| Zabashnyĭ, SI | 1 |
| Smirnova, EV | 1 |
| Kobeliatskiĭ, IuIu | 1 |
| Romics, I | 1 |
| Molnár, DL | 1 |
| Timberg, G | 1 |
| Mrklic, B | 1 |
| Jelakovic, B | 1 |
| Köszegi, G | 1 |
| Blaskó, G | 1 |
| MAKLARI, L | 1 |
| Snir, N | 1 |
| Moskovitz, B | 1 |
| Nativ, O | 1 |
| Margel, D | 1 |
| Sandovski, U | 1 |
| Sulkes, J | 1 |
| Livne, PM | 1 |
| Lifshitz, DA | 1 |
| Lundstam, SO | 1 |
| Leissner, KH | 1 |
| Wåhlander, LA | 1 |
| Kral, JG | 1 |
| Goldman, G | 1 |
| Kahn, PJ | 1 |
| Alon, R | 1 |
| Wiznitzer, T | 1 |
| Jönsson, PE | 2 |
| Olsson, AM | 1 |
| Petersson, BA | 2 |
| Johansson, K | 1 |
| Bick, C | 1 |
| Suckow, B | 1 |
| Heil, G | 1 |
| Erichsen, C | 1 |
| Holmin, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain, Double Blinded Randomized Placebo Controlled Trial[NCT05759364] | 128 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Abdominal Cramps
| Article | Year |
|---|---|
NSAIDS for renal and biliary colic: intramuscular diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract Diseases; Codeine; Colic; Diclofenac; Drug Co | 1987 |
8 trials available for papaverine and Abdominal Cramps
| Article | Year |
|---|---|
Role of papaverine hydrochloride administration in patients with intractable renal colic: randomized prospective trial.
Topics: Adolescent; Adult; Colic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Pa | 2008 |
[Preparation no-shpa forte for the treatment of renal colic].
Topics: Adult; Aged; Colic; Female; Hemodynamics; Humans; Kidney Diseases; Male; Middle Aged; Papaverine; Pa | 2003 |
The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones.
Topics: Acute Disease; Adult; Colic; Double-Blind Method; Female; Humans; Kidney Calculi; Male; Pain Measure | 2003 |
Papaverine hydrochloride for the treatment of renal colic: an old drug revisited. A prospective, randomized study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Drug Therapy, Combination; Female | 2008 |
Prostaglandin-synthetase inhibition with diclofenac sodium in treatment of renal colic: comparison with use of a narcotic analgesic.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Codeine; Colic; Cyclooxygenase Inhibitors; Diclofenac; | 1982 |
Biliary colic treatment and acute cholecystitis prevention by prostaglandin inhibitor.
Topics: Acute Disease; Biliary Tract Diseases; Cholecystitis; Cholelithiasis; Clinical Trials as Topic; Coli | 1989 |
Intravenous indomethacin and oxycone-papaverine in the treatment of acute renal colic. A double-blind study.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Codeine; Colic; Double-Blind Method; Drug Comb | 1987 |
Double-blind evaluation of intravenous indomethacin and oxycone-papaverine in the treatment of acute biliary pain.
Topics: Adolescent; Adult; Aged; Analgesics; Biliary Tract Diseases; Cholecystitis; Clinical Trials as Topic | 1985 |
2 other studies available for papaverine and Abdominal Cramps
| Article | Year |
|---|---|
EXPERIENCE OBTAINED WITH A NEW SPASMOLYTIC DRUG (NO-SPA).
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cholelithiasis; Colic; Colitis; Duodenal Ulcer; | 1963 |
[Indomethacin in the treatment of ureteral colic caused by calculi].
Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Colic; Dipyrone; Drug Therapy, Combination; Female | 1986 |