papaverine has been researched along with ADPKD in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the Han:SPRD rat model of autosomal dominant polycystic kidney disease (ADPKD), gene transfer occurred into the vasculature, some epithelial cysts and interstitial cells." | 1.29 | In vivo adenovirus-mediated gene transfer into normal and cystic rat kidneys. ( Cowley, BD; Nicolson, AG; Rosen, S; Sukhatme, VP; Zhu, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, G | 1 |
| Nicolson, AG | 1 |
| Cowley, BD | 1 |
| Rosen, S | 1 |
| Sukhatme, VP | 1 |
1 other study available for papaverine and ADPKD
| Article | Year |
|---|---|
In vivo adenovirus-mediated gene transfer into normal and cystic rat kidneys.
Topics: Adenoviridae; Animals; beta-Galactosidase; Cold Temperature; Disease Models, Animal; Dopamine; Gene | 1996 |