Page last updated: 2024-11-02

pantoprazole and Stomach Neoplasms

pantoprazole has been researched along with Stomach Neoplasms in 26 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
" The present study was conducted to explore the effect of pantoprazole on gastric adenocarcinoma through the regulation of Wnt/β-catenin signaling."7.79Effect of pantoprazole on human gastric adenocarcinoma SGC7901 cells through regulation of phospho‑LRP6 expression in Wnt/β-catenin signaling. ( Chen, M; Guo, H; Huang, S; Liu, P; Shen, W; Shen, Y; Zhang, L; Zou, X, 2013)
"To investigate reversal effects of pantoprazole (PPZ) on multidrug resistance (MDR) in human gastric adenocarcinoma cells in vivo and in vitro."7.78Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo. ( Chen, M; Huang, SL; Yang, VW; Zhang, B; Zhang, XQ; Zhu, H; Zou, XP, 2012)
" The present study was conducted to explore the effect of pantoprazole on gastric adenocarcinoma through the regulation of Wnt/β-catenin signaling."3.79Effect of pantoprazole on human gastric adenocarcinoma SGC7901 cells through regulation of phospho‑LRP6 expression in Wnt/β-catenin signaling. ( Chen, M; Guo, H; Huang, S; Liu, P; Shen, W; Shen, Y; Zhang, L; Zou, X, 2013)
"To investigate reversal effects of pantoprazole (PPZ) on multidrug resistance (MDR) in human gastric adenocarcinoma cells in vivo and in vitro."3.78Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo. ( Chen, M; Huang, SL; Yang, VW; Zhang, B; Zhang, XQ; Zhu, H; Zou, XP, 2012)
" We aimed to prospectively compare the effects of continuous infusion and intermittent dosing with pantoprazole on preventing gastric ESD-related bleeding."2.90Continuous Infusion versus Intermittent Dosing with Pantoprazole for Gastric Endoscopic Submucosal Dissection. ( Baek, DH; Jeon, HK; Kim, DU; Kim, GH; Lee, BE; Seo, JH; Song, GA, 2019)
" However, effective dosing or scheduling of proton pump inhibitors for the prevention of delayed bleeding after endoscopic resection remains unclear."2.84Standard and double-dose intravenous proton pump inhibitor injections for prevention of bleeding after endoscopic resection. ( Choe, JW; Hyun, JJ; Jung, SW; Jung, YK; Kim, SY; Koo, JS; Lee, SW; Yim, HJ, 2017)
" Several studies have linked the long-term use of PPIs to a potentially increased risk of gastric cancer."1.72Suppression of vacuolar-type ATPase and induction of endoplasmic reticulum stress by proton pump inhibitors. ( Lee, WP, 2022)
"However, whether PPIs suppress gastric cancer by targeting TERT remains elusive."1.51Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression. ( Cao, Y; Kang, W; Ling, T; Qian, L; Wang, L; Xu, G; Zhang, B; Zhang, W; Zhao, D; Zhaxi, P; Zou, X, 2019)
"We compared the viability of gastric cancer cells and epithelia cells in buffered and unbuffered culture conditions with PPZ treatment by WST-8 assay."1.39Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway. ( Chen, M; Ding, X; Huang, S; Zhang, X; Zou, X, 2013)
"This is the first report of a gastric Burkitt's lymphoma responding to H pylori eradication."1.35Complete remission of gastric Burkitt's lymphoma after eradication of Helicobacter pylori. ( Baia, M; Baumgaertner, I; Charachon, A; Copie-Bergman, C; Delchier, JC; Haioun, C; Levy, M; Sobhani, I, 2009)
"Treatment of human gastric cancer cells with proton pump inhibitors significantly attenuated cell viability in a time- and dose-dependent manner."1.35Blockage of intracellular proton extrusion with proton extrusions with proton pump inhibitor induces apoptosis in gastric cancer. ( Cheong, JY; Cho, SW; Kim, DK; Lee, KJ; Park, HJ; Yeo, M, 2008)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (38.46)29.6817
2010's15 (57.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Lee, WP1
Souto Filho, JTD1
Lemos, LVB1
Vieira Junior, MC1
Barboza, KP1
Castelar, BM1
Ribeiro, AEL1
da Silva, FC1
Lee, BE1
Kim, GH1
Song, GA1
Seo, JH1
Jeon, HK1
Baek, DH1
Kim, DU1
Zhang, B3
Ling, T2
Zhaxi, P1
Cao, Y1
Qian, L1
Zhao, D1
Kang, W1
Zhang, W1
Wang, L2
Xu, G2
Zou, X5
Shen, W2
Chen, M5
Shen, Y2
Huang, S4
Guo, H1
Zhang, L2
Liu, P1
Ding, X1
Zhang, X2
Baeg, MK1
Choi, MG2
Moon, SJ1
Lim, CH1
Kim, JS1
Cho, YK2
Park, JM2
Lee, IS2
Kim, SW2
Choi, KY2
Yang, Y1
Shi, X1
Liao, W1
Cheng, AS1
Yan, H1
Fang, C1
Zhang, S1
Shen, S1
Chen, G1
Lv, Y1
Zhuge, Y1
Schneider, JL1
Kolitsopoulos, F1
Corley, DA1
Jung, YS1
Kim, KO1
Lee, SH2
Jang, BI1
Kim, TN1
Jung, SW1
Kim, SY1
Choe, JW1
Hyun, JJ1
Jung, YK1
Koo, JS1
Yim, HJ1
Lee, SW1
Feng, S1
Zheng, Z1
Feng, L1
Yang, L1
Chen, Z1
Lin, Y1
Gao, Y1
Chen, Y1
Oh, TH1
Jung, HY1
Choi, KD1
Lee, GH2
Song, HJ1
Choi, KS1
Chung, JW1
Byeon, JS1
Myung, SJ1
Yang, SK1
Kim, JH1
Baumgaertner, I1
Copie-Bergman, C1
Levy, M1
Haioun, C1
Charachon, A1
Baia, M1
Sobhani, I1
Delchier, JC1
Kim, JY1
Kim, N1
Park, HK1
Jo, HJ1
Shin, CM1
Park, YS1
Hwang, JH1
Kim, JW1
Jeong, SH1
Lee, DH1
Nam, RH1
Kim, JM1
Lee, JH1
Jung, HC1
Song, IS1
Wu, Y1
Kım, KJ1
Park, MI1
Park, SJ1
Cho, SW3
Moon, W1
Kim, GM1
Kim, WM1
Huang, SL1
Zhang, XQ1
Zhu, H1
Yang, VW1
Zou, XP1
Hiramoto, JS1
Terdiman, JP1
Norton, JA1
Yeo, M2
Kim, DK2
Kim, YB1
Oh, TY1
Lee, JE1
Kim, HC1
Hahm, KB1
Wöhrer, S1
Bartsch, R1
Hejna, M1
Drach, J1
Raderer, M1
Oh, JH1
Dong, MS1
Paik, CN1
Jeong, JJ1
Han, SW1
Chung, IS1
Jeong, HK1
Park, CH1
Jun, CH1
Kim, HI1
Kim, HS1
Choi, SK1
Rew, JS1
Park, HJ1
Cheong, JY1
Lee, KJ1

Reviews

3 reviews available for pantoprazole and Stomach Neoplasms

ArticleYear
Long-term complete remission of primary gastric plasmacytoma following endoscopic resection.
    Annals of hematology, 2017, Volume: 96, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Clarithromycin; Gastric Mucosa; Gastroscopy; H

2017
Evidence-based analysis: postoperative gastric bleeding: etiology and prevention.
    Surgical oncology, 2003, Volume: 12, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Cost-Benefit Analysis; D

2003
[Eradication of Helicobacter pylori].
    Krankenpflege Journal, 2005, Volume: 43, Issue:4-6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2005

Trials

7 trials available for pantoprazole and Stomach Neoplasms

ArticleYear
Continuous Infusion versus Intermittent Dosing with Pantoprazole for Gastric Endoscopic Submucosal Dissection.
    Gut and liver, 2019, 01-15, Volume: 13, Issue:1

    Topics: Aged; Endoscopic Mucosal Resection; Female; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Infusi

2019
Preprocedural rabeprazole treatment before endoscopic submucosal dissection for gastric neoplasms.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Dissection; Female; Gastric Mucosa; Gastrointestinal

2014
[Comparison on Oral versus Intravenous Proton Pump Inhibitors for Prevention of Bleeding after Endoscopic Submucosal Dissection of Gastric Lesions].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2016, Volume: 67, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Aged; Anticoagulants; Endoscopic Muco

2016
Standard and double-dose intravenous proton pump inhibitor injections for prevention of bleeding after endoscopic resection.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Aged; Dose-Response Relationship, Drug; Drug Admin

2017
Effective administration method of intravenous proton pump inhibitor: a novel testing using a BRAVO catheterless pH monitoring system.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2011, Volume: 22, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Analysis of Variance; Female; Gastric Acidity Determi

2011
Low-dose intravenous pantoprazole for optimal inhibition of gastric acid in Korean patients.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylas

2007
A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection.
    Journal of Korean medical science, 2007, Volume: 22, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Dissection; Famotidine; Female; Ga

2007

Other Studies

16 other studies available for pantoprazole and Stomach Neoplasms

ArticleYear
Suppression of vacuolar-type ATPase and induction of endoplasmic reticulum stress by proton pump inhibitors.
    Journal of the Chinese Medical Association : JCMA, 2022, 09-01, Volume: 85, Issue:9

    Topics: Activating Transcription Factor 6; Dexlansoprazole; Endoplasmic Reticulum Stress; Esomeprazole; Huma

2022
Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression.
    Cancer letters, 2019, 06-28, Volume: 452

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Chromatin Assembly and Disassembly;

2019
Effect of pantoprazole on human gastric adenocarcinoma SGC7901 cells through regulation of phospho‑LRP6 expression in Wnt/β-catenin signaling.
    Oncology reports, 2013, Volume: 30, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Apoptosis; Cell Line, Tumor; Cell Prolifera

2013
Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway.
    International immunopharmacology, 2013, Volume: 17, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tum

2013
Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial-mesenchymal transition.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western;

2015
Risk of gastric cancer, gastrointestinal cancers and other cancers: a comparison of treatment with pantoprazole and other proton pump inhibitors.
    Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; California; Cohort Studies; Dose-R

2016
Proton pump inhibitor pantoprazole inhibits the proliferation, self‑renewal and chemoresistance of gastric cancer stem cells via the EMT/β‑catenin pathways.
    Oncology reports, 2016, Volume: 36, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor;

2016
Degree of healing and healing-associated factors of endoscopic submucosal dissection-induced ulcers after pantoprazole therapy for 4 weeks.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Anti-Ulce

2009
Complete remission of gastric Burkitt's lymphoma after eradication of Helicobacter pylori.
    World journal of gastroenterology, 2009, Dec-07, Volume: 15, Issue:45

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Burkitt Lymphoma; Female; Gastric

2009
[Primary antibiotic resistance of Helicobacter pylori strains and eradication rate according to gastroduodenal disease in Korea].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Volume: 58, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Chronic Di

2011
Effects of pantoprazole as a HIF-1α inhibitor on human gastric adenocarcinoma sgc-7901 cells.
    Neoplasma, 2012, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Animals; Anti-Ulcer Agents; Apoptosis; Blot

2012
Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Animals; Antineoplastic Agents; ATP Binding

2012
[Patient with increased stomach cancer risk. Helicobacter can cause damage here].
    MMW Fortschritte der Medizin, 2002, Oct-24, Volume: 144, Issue:43

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Therapy,

2002
Selective induction of apoptosis with proton pump inhibitor in gastric cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-15, Volume: 10, Issue:24

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Annexin A5; Anti-Ulcer Agents; Apoptosis; Benzimid

2004
Routine application of the proton-pump inhibitor pantoprazole in patients with gastric lymphoma undergoing chemotherapy.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-

2005
Blockage of intracellular proton extrusion with proton extrusions with proton pump inhibitor induces apoptosis in gastric cancer.
    Cancer science, 2008, Volume: 99, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apoptosis; Caspases; Cell Line, Tumor; Culture Media; Enzym

2008