Page last updated: 2024-11-02

pantoprazole and Pregnancy

pantoprazole has been researched along with Pregnancy in 7 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"We followed up 295 pregnancies exposed to omeprazole [233 in the first trimester (T1)], 62 to lansoprazole (55 in T1) and 53 to pantoprazole (47 in T1), and compared pregnancy outcome to that of 868 European Network of Teratology Information Services controls."5.11The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study. ( Arnon, J; Clementi, M; De Santis, M; Diav-Citrin, O; Malm, H; Ornoy, A; Robert-Gnansia, E; Schaefer, C; Shechtman, S; Valti, E; van Tonningen, MR, 2005)
" Pantoprazole-related microscopic findings in the stomach consisted of increased mucosal height, glandular necrosis, and glandular dilation at all doses; and ECL cell hyperplasia, parietal cell vacuolation, and atrophy of chief cells are noted at 10 and/or 30 mg/kg/day."3.77Toxicology and toxicokinetics of oral pantoprazole in neonatal and juvenile dogs. ( Cappon, GD; Hurtt, ME; Mansell, P; Minck, D; Robinson, K, 2011)
" In the present article, the adverse effects of PPIs are reviewed, with special emphasis on those related to their continued administration and on the special circumstances of patients, as in the case of the elderly, those with liver failure, pregnant and breastfeeding mothers and children."2.43[Safety of proton pump inhibitors]. ( Esplugues, JV; Martí-Cabrera, M; Ponce, J, 2006)
"Pantoprazole is a proton pump inhibitor which has recently had its clinical license extended to include maintenance therapy for the treatment of reflux oesophagitis, Helicobacter pylori eradication and short-term intravenous administration."2.40Pantoprazole, Prout and the proton pump. ( Modlin, I; Playford, RJ; Podas, T, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Terranova, C1
Petrella, C1
Improta, G1
Severini, C1
Signore, F1
Damiani, P1
Plotti, F1
Scarpignato, C1
Angioli, R1
Schmutz, JL1
Trechot, P1
Mansell, P1
Robinson, K1
Minck, D1
Hurtt, ME1
Cappon, GD1
Diav-Citrin, O1
Arnon, J1
Shechtman, S1
Schaefer, C1
van Tonningen, MR1
Clementi, M1
De Santis, M1
Robert-Gnansia, E1
Valti, E1
Malm, H1
Ornoy, A1
Esplugues, JV1
Martí-Cabrera, M1
Ponce, J1
Playford, RJ1
Podas, T1
Modlin, I1

Reviews

2 reviews available for pantoprazole and Pregnancy

ArticleYear
[Safety of proton pump inhibitors].
    Medicina clinica, 2006, Nov-25, Volume: 127, Issue:20

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Age Factors; Aged; Animal

2006
Pantoprazole, Prout and the proton pump.
    Hospital medicine (London, England : 1998), 1999, Volume: 60, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Drug Interactions; Femal

1999

Trials

1 trial available for pantoprazole and Pregnancy

ArticleYear
The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study.
    Alimentary pharmacology & therapeutics, 2005, Feb-01, Volume: 21, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abnormalities, Drug-Induced; Adult; Anti-Ulcer Agents; Benz

2005

Other Studies

4 other studies available for pantoprazole and Pregnancy

ArticleYear
Relaxant effect of proton pump inhibitors on in vitro myometrium from pregnant women.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apamin; Calcium; Dinoprostone; Esomeprazole; Female; Humans

2014
[Lupus erythematosus and proto-pump inhibitors].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Autoantibodies; Biopsy; Diagnosis, Differential; Eso

2014
Pantoprazole available without a prescription: new status. Better than H2 receptor agonists, but not for pregnant women.
    Prescrire international, 2009, Volume: 18, Issue:104

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Anti-Ulcer Agents; Clinical Trials as Topic; Cont

2009
Toxicology and toxicokinetics of oral pantoprazole in neonatal and juvenile dogs.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2011, Volume: 92, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abnormalities, Drug-Induced; Animals; Animals, Newborn; Ant

2011