pantoprazole has been researched along with Liver Cirrhosis in 7 studies
Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Excerpt | Relevance | Reference |
---|---|---|
"This observation further supports the notion that pantoprazole can induce acute hepatocellular hepatitis, and it strongly suggests that it may trigger acute cholangitis and autoimmune liver injury." | 7.88 | Pantoprazole-induced autoimmune chronic hepatitis. ( Larrey, D; Meunier, L; Pageaux, GP; Ursic-Bedoya, J, 2018) |
"This observation further supports the notion that pantoprazole can induce acute hepatocellular hepatitis, and it strongly suggests that it may trigger acute cholangitis and autoimmune liver injury." | 3.88 | Pantoprazole-induced autoimmune chronic hepatitis. ( Larrey, D; Meunier, L; Pageaux, GP; Ursic-Bedoya, J, 2018) |
" Following a single oral dose of 40 mg, Cmax is approximately 2." | 2.68 | Pharmacokinetics of pantoprazole in man. ( Bliesath, H; Hartmann, M; Huber, R; Lühmann, R; Steinijans, VW; Zech, K, 1996) |
"In 84 consecutive cirrhotic patients, bacterial infection risk was prospectively assessed and related to PPI use." | 1.38 | Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability. ( de Rooij, FW; Huisman, EJ; Renooij, W; Siersema, PD; van Erpecum, KJ; van Hoek, B; van Vlerken, LG, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (71.43) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors | Studies |
---|---|
Labenz, C | 1 |
Kostev, K | 1 |
Galle, PR | 1 |
Wörns, MA | 1 |
Labenz, J | 1 |
Tanislav, C | 1 |
Adarkwah, CC | 1 |
Meunier, L | 1 |
Ursic-Bedoya, J | 1 |
Pageaux, GP | 1 |
Larrey, D | 1 |
Yang, SC | 1 |
Chen, JC | 1 |
Tai, WC | 1 |
Wu, CK | 1 |
Lee, CH | 1 |
Wu, KL | 1 |
Chiu, YC | 1 |
Wang, JH | 1 |
Lu, SN | 1 |
Chuah, SK | 1 |
Calcagno, A | 1 |
Trentalange, A | 1 |
Simiele, M | 1 |
Marinaro, L | 1 |
Patti, F | 1 |
Tettoni, MC | 1 |
Trentini, L | 1 |
Di Perri, G | 1 |
DʼAvolio, A | 1 |
Bonora, S | 1 |
Tsai, CF | 1 |
Chen, MH | 1 |
Wang, YP | 1 |
Chu, CJ | 1 |
Huang, YH | 1 |
Lin, HC | 1 |
Hou, MC | 1 |
Lee, FY | 1 |
Su, TP | 1 |
Lu, CL | 1 |
van Vlerken, LG | 1 |
Huisman, EJ | 1 |
van Hoek, B | 1 |
Renooij, W | 1 |
de Rooij, FW | 1 |
Siersema, PD | 1 |
van Erpecum, KJ | 1 |
Huber, R | 1 |
Hartmann, M | 1 |
Bliesath, H | 1 |
Lühmann, R | 1 |
Steinijans, VW | 1 |
Zech, K | 1 |
1 trial available for pantoprazole and Liver Cirrhosis
Article | Year |
---|---|
Pharmacokinetics of pantoprazole in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Aged; Anti-Ulcer A | 1996 |
6 other studies available for pantoprazole and Liver Cirrhosis
Article | Year |
---|---|
Proton pump inhibitor use is associated with a variety of infections in patients with liver cirrhosis.
Topics: Bacterial Infections; Case-Control Studies; Databases, Factual; Female; Germany; Humans; Liver Cirrh | 2020 |
Pantoprazole-induced autoimmune chronic hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cholangitis; Cholestasis; Female; Hepatitis, Autoimmune; Hum | 2018 |
The influential roles of antibiotics prophylaxis in cirrhotic patients with peptic ulcer bleeding after initial endoscopic treatments.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibiotic | 2014 |
Rilpivirine Pharmacokinetics in 3 HIV-Positive Patients With Liver Cirrhosis Concomitantly Receiving Pantoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-HIV Agents; Drug Interactions; HIV Infections; Humans; | 2015 |
Proton Pump Inhibitors Increase Risk for Hepatic Encephalopathy in Patients With Cirrhosis in A Population Study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administrative Claims, Healthcare; Adult; Aged; Case-Contro | 2017 |
Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Animals; Bacteria; Bacterial Infections; Cohor | 2012 |