Page last updated: 2024-11-02

pantoprazole and Laryngitis

pantoprazole has been researched along with Laryngitis in 5 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Laryngitis: Inflammation of the LARYNGEAL MUCOSA, including the VOCAL CORDS. Laryngitis is characterized by irritation, edema, and reduced pliability of the mucosa leading to VOICE DISORDERS such as APHONIA and HOARSENESS.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to determine the clinical and pH-metric effect of treatment with pantoprazole 80 mg for 8 weeks in patients with ear, nose, and throat (ENT) manifestations of gastroesophageal reflux disease associated with pathological proximal acid exposure."9.14Effect of pantoprazole in patients with chronic laryngitis and pharyngitis related to gastroesophageal reflux disease: clinical, proximal, and distal pH monitoring results. ( Ben Mustapha, N; Besbes, G; Bibani, N; Boubaker, J; Filali, A; Kallel, L; Karoui, S; Matri, S; Sahtout, S; Serghini, M; Zouiten, L, 2010)
" Both pantoprazole and placebo resulted in a marked improvement in laryngitis scores (decrease of 8."9.10Effect of pantoprazole on the course of reflux-associated laryngitis: a placebo-controlled double-blind crossover study. ( Eherer, AJ; Friedrich, G; Habermann, W; Hammer, HF; Kiesler, K; Krejs, GJ, 2003)
" The aim of this study was to determine the clinical and pH-metric effect of treatment with pantoprazole 80 mg for 8 weeks in patients with ear, nose, and throat (ENT) manifestations of gastroesophageal reflux disease associated with pathological proximal acid exposure."5.14Effect of pantoprazole in patients with chronic laryngitis and pharyngitis related to gastroesophageal reflux disease: clinical, proximal, and distal pH monitoring results. ( Ben Mustapha, N; Besbes, G; Bibani, N; Boubaker, J; Filali, A; Kallel, L; Karoui, S; Matri, S; Sahtout, S; Serghini, M; Zouiten, L, 2010)
" Both pantoprazole and placebo resulted in a marked improvement in laryngitis scores (decrease of 8."5.10Effect of pantoprazole on the course of reflux-associated laryngitis: a placebo-controlled double-blind crossover study. ( Eherer, AJ; Friedrich, G; Habermann, W; Hammer, HF; Kiesler, K; Krejs, GJ, 2003)
"Extraesophageal manifestations of gastroesophageal reflux disease (GERD) can include upper airway disorders, asthma and chronic cough."2.43Extraesophageal manifestations of GERD: diagnosis and therapy. ( Halstead, LA, 2005)
"Gastroesophageal reflux (GER) is associated with a variety of laryngopharyngeal signs and symptoms."1.31Effect of aggressive therapy on laryngeal symptoms and voice characteristics in patients with gastroesophageal reflux. ( Fuleihan, N; Hamdan, AL; Sharara, AI; Younes, A, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karoui, S1
Bibani, N1
Sahtout, S1
Zouiten, L1
Kallel, L1
Matri, S1
Serghini, M1
Ben Mustapha, N1
Boubaker, J1
Besbes, G1
Filali, A1
Eherer, AJ1
Habermann, W2
Hammer, HF1
Kiesler, K1
Friedrich, G2
Krejs, GJ1
Halstead, LA1
Eherer, A1
Lindbichler, F1
Raith, J1
Hamdan, AL1
Sharara, AI1
Younes, A1
Fuleihan, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pantoprazole and Laryngitis

ArticleYear
Extraesophageal manifestations of GERD: diagnosis and therapy.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41 Suppl B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease;

2005

Trials

2 trials available for pantoprazole and Laryngitis

ArticleYear
Effect of pantoprazole in patients with chronic laryngitis and pharyngitis related to gastroesophageal reflux disease: clinical, proximal, and distal pH monitoring results.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2010, Volume: 23, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Chronic Disease; Esophageal pH Monitorin

2010
Effect of pantoprazole on the course of reflux-associated laryngitis: a placebo-controlled double-blind crossover study.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Cross-Over

2003

Other Studies

2 other studies available for pantoprazole and Laryngitis

ArticleYear
Ex juvantibus approach for chronic posterior laryngitis: results of short-term pantoprazole therapy.
    The Journal of laryngology and otology, 1999, Volume: 113, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chronic Disease;

1999
Effect of aggressive therapy on laryngeal symptoms and voice characteristics in patients with gastroesophageal reflux.
    Acta oto-laryngologica, 2001, Volume: 121, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Cisapride; Gastroesophag

2001