Page last updated: 2024-11-02

pantoprazole and Kidney Diseases

pantoprazole has been researched along with Kidney Diseases in 7 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" Following a single oral dose of 40 mg, Cmax is approximately 2."2.68Pharmacokinetics of pantoprazole in man. ( Bliesath, H; Hartmann, M; Huber, R; Lühmann, R; Steinijans, VW; Zech, K, 1996)
" If two drugs of the same class have a similar dose-efficacy profile, then the favourable/unfavourable balance of the pharmacokinetic characteristics of the drugs may determine the drug of choice."2.39Pharmacokinetics--a relevant factor for the choice of a drug? ( Benet, LZ; Zech, K, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Schefold, JC1
Krag, M1
Marker, S1
Perner, A1
Wetterslev, J1
Wise, MP1
Borthwick, M1
Bendel, S1
Keus, F1
Guttormsen, AB1
Lange, T1
Møller, MH1
Ismail, RS1
El-Awady, MS1
Hassan, MH1
Kohansal, P1
Rajai, N1
Dehpour, AR1
Rashidian, A1
Shafaroodi, H1
Lai, B1
Cervelli, MJ1
Benet, LZ1
Zech, K2
Huber, R1
Hartmann, M1
Bliesath, H1
Lühmann, R1
Steinijans, VW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sup-Icu RENal (SIREN) - a Sub-analysis of the Prospective SUP (Stress Ulcer Prophylaxis)-ICU Trial on the Risk of GI- Bleeding in ICU Patients Receiving Renal Replacement Therapy[NCT02718261]Phase 43,350 participants (Actual)Interventional2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pantoprazole and Kidney Diseases

ArticleYear
Pharmacokinetics--a relevant factor for the choice of a drug?
    Alimentary pharmacology & therapeutics, 1994, Volume: 8 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Aging; Benzimidazoles; Biological Ava

1994

Trials

3 trials available for pantoprazole and Kidney Diseases

ArticleYear
Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial.
    American journal of nephrology, 2019, Volume: 50, Issue:4

    Topics: Acute Kidney Injury; Aged; Clostridium Infections; Critical Care; Cross Infection; Female; Gastroint

2019
Effect of gastric acid suppression with pantoprazole on the efficacy of sevelamer hydrochloride as a phosphate binder in haemodialysis patients: a pilot study.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Biomarkers; Chelating Agents; Cross-Over Studies; Dou

2012
Pharmacokinetics of pantoprazole in man.
    International journal of clinical pharmacology and therapeutics, 1996, Volume: 34, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Aged; Anti-Ulcer A

1996

Other Studies

3 other studies available for pantoprazole and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
Pantoprazole abrogated cisplatin-induced nephrotoxicity in mice via suppression of inflammation, apoptosis, and oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cisplatin; Cytokin

2020
The protective effect of acute pantoprazole pretreatment on renal ischemia/reperfusion injury in rats.
    Fundamental & clinical pharmacology, 2019, Volume: 33, Issue:4

    Topics: Animals; Blood Urea Nitrogen; Blotting, Western; Creatinine; Dose-Response Relationship, Drug; Kidne

2019