pantoprazole has been researched along with Heart Failure in 4 studies
Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the intestinal barrier function (IBF) state of patients with acute myocardial infarction-heart failure (AMI-HF), and to compare the therapeutic effects of rhubarb and Pantoprazole (proton pump inhibitor)." | 5.16 | [Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart]. ( Mao, XB; Mao, Y; Wang, SQ, 2012) |
| "Pantoprazole was infused at rates of 3 and 10 mg/kg/min intravenously, and hemodynamic parameters were recorded." | 1.42 | Negative hemodynamic effects of pantoprazole at high infusion rates in mice. ( Didié, M; Hasenfuß, G; Jacobshagen, C; Schillinger, W; Seidler, T; Sossalla, S; Teucher, N; Unsöld, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Unsöld, B | 1 |
| Teucher, N | 2 |
| Didié, M | 1 |
| Sossalla, S | 3 |
| Jacobshagen, C | 1 |
| Seidler, T | 1 |
| Schillinger, W | 3 |
| Hasenfuß, G | 1 |
| Schotola, H | 1 |
| Schmitto, J | 1 |
| Toischer, K | 1 |
| Sohns, C | 1 |
| Schwörer, H | 2 |
| Hasenfuss, G | 2 |
| Maier, L | 1 |
| Mao, XB | 1 |
| Wang, SQ | 1 |
| Mao, Y | 1 |
| Kettlewell, S | 1 |
| Werner, C | 1 |
| Raddatz, D | 1 |
| Elgner, A | 1 |
| Tenderich, G | 1 |
| Pieske, B | 1 |
| Ramadori, G | 1 |
| Schöndube, FA | 1 |
| Kögler, H | 1 |
| Kockskämper, J | 1 |
| Maier, LS | 1 |
| Smith, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart Failure[NCT00699361] | Phase 3 | 0 participants (Actual) | Interventional | 2008-08-31 | Withdrawn (stopped due to Study withdrawn for financial issues) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for pantoprazole and Heart Failure
| Article | Year |
|---|---|
[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Endotoxins; Female; Glutamine; Heart Failure; Humans; | 2012 |
3 other studies available for pantoprazole and Heart Failure
| Article | Year |
|---|---|
Negative hemodynamic effects of pantoprazole at high infusion rates in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Blood Pressure; Disease Models, Animal; Dose-Respo | 2015 |
Effects of different proton pump inhibitors on cardiac contractility in isolated human failing myocardium.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dose-Response Relationship, Drug; Esomeprazole; Heart Failu | 2011 |
Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits: evaluation of mechanisms.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Actin Cytoskeleton; Aniline Compounds; Animals; Anti-Ulcer | 2007 |