Compounds > pantoprazole
Page last updated: 2024-11-02

pantoprazole and Chemical and Drug Induced Liver Injury

pantoprazole has been researched along with Chemical and Drug Induced Liver Injury in 9 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
"This observation further supports the notion that pantoprazole can induce acute hepatocellular hepatitis, and it strongly suggests that it may trigger acute cholangitis and autoimmune liver injury."7.88Pantoprazole-induced autoimmune chronic hepatitis. ( Larrey, D; Meunier, L; Pageaux, GP; Ursic-Bedoya, J, 2018)
"This observation further supports the notion that pantoprazole can induce acute hepatocellular hepatitis, and it strongly suggests that it may trigger acute cholangitis and autoimmune liver injury."3.88Pantoprazole-induced autoimmune chronic hepatitis. ( Larrey, D; Meunier, L; Pageaux, GP; Ursic-Bedoya, J, 2018)
" Eight days before admission she had started and continued to take pantoprazole because of symptoms of gastroesophageal reflux."3.72[Pantoprazole-induced hepatitis]. ( Cordes, A; Maier, KP; Vogt, W, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Meunier, L1
Ursic-Bedoya, J1
Pageaux, GP1
Larrey, D1
Aslan, M1
Celik, Y1
Karadas, S1
Olmez, S1
Cifci, A1
Sandig, C1
Flechtenmacher, C1
Stremmel, W1
Eisenbach, C1
Cordes, A1
Vogt, W1
Maier, KP1
Wellhöfer, B1
Darabi, K1

Reviews

1 review available for pantoprazole and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

8 other studies available for pantoprazole and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Pantoprazole-induced autoimmune chronic hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Cholangitis; Cholestasis; Female; Hepatitis, Autoimmune; Hum

2018
Liver hepatotoxicity associated with pantoprazole: a rare case report.
    Wiener klinische Wochenschrift, 2014, Volume: 126, Issue:11-12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Ulcer Agents; Chemical and Drug Induce

2014
Pantoprazole induces severe acute hepatitis.
    Zeitschrift fur Gastroenterologie, 2011, Volume: 49, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chemical and Drug Induced Liver Injury; Female; Humans; Liv

2011
[Pantoprazole-induced hepatitis].
    Deutsche medizinische Wochenschrift (1946), 2003, Mar-21, Volume: 128, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdomen; Abdominal Pain; Anti-Ulcer Agents; Benzimidazoles;

2003
[Pantoprazole-induced hepatitis].
    Deutsche medizinische Wochenschrift (1946), 2003, Jul-04, Volume: 128, Issue:27

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Ulcer Agents; Benzimidazoles; Chemical

2003
Proton-pump-inhibitor-induced hepatitis.
    Southern medical journal, 2005, Volume: 98, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Chemical and Drug

2005