Page last updated: 2024-11-02

pantoprazole and Cardiovascular Stroke

pantoprazole has been researched along with Cardiovascular Stroke in 8 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"In this randomized crossover study analyzing patients after acute myocardial infarction, omeprazole coadministration showed a significant pharmacodynamic interaction with clopidogrel, whereas pantoprazole did not."9.15Omeprazole, but not pantoprazole, reduces the antiplatelet effect of clopidogrel: a randomized clinical crossover trial in patients after myocardial infarction evaluating the clopidogrel-PPIs drug interaction. ( Albuquerque, A; Araújo, C; Fontes-Carvalho, R; Pimentel-Nunes, P; Ribeiro, VG, 2011)
"The purpose of this study was to determine the readmission rate for acute myocardial infarction (AMI) in patients discharged on clopidogrel and a proton-pump inhibitor (PPI) versus patients discharged on clopidogrel alone after experiencing an AMI and undergoing stent placement."7.76Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction. ( Binkley, P; Donnally, MR; Evanchan, J; Mazzaferri, E, 2010)
"105 patients with ST elevation myocardial infarction (STEMI), treated with percutaneous coronary angioplasty (PCI) and who received dual antiplatelet therapy, were randomized between pantoprazole (n=54) or ranitidine (n=51)."5.17Pantoprazole significantly interferes with antiplatelet effect of clopidogrel: results of a pilot randomized trial. ( Berti, S; Della Pina, F; Dushpanova, A; Gianetti, J; Giusti, B; Marcucci, R; Parri, MS; Saracini, C, 2013)
"To clarify the intestinal barrier function (IBF) state of patients with acute myocardial infarction-heart failure (AMI-HF), and to compare the therapeutic effects of rhubarb and Pantoprazole (proton pump inhibitor)."5.16[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart]. ( Mao, XB; Mao, Y; Wang, SQ, 2012)
"In this randomized crossover study analyzing patients after acute myocardial infarction, omeprazole coadministration showed a significant pharmacodynamic interaction with clopidogrel, whereas pantoprazole did not."5.15Omeprazole, but not pantoprazole, reduces the antiplatelet effect of clopidogrel: a randomized clinical crossover trial in patients after myocardial infarction evaluating the clopidogrel-PPIs drug interaction. ( Albuquerque, A; Araújo, C; Fontes-Carvalho, R; Pimentel-Nunes, P; Ribeiro, VG, 2011)
"The purpose of this study was to determine the readmission rate for acute myocardial infarction (AMI) in patients discharged on clopidogrel and a proton-pump inhibitor (PPI) versus patients discharged on clopidogrel alone after experiencing an AMI and undergoing stent placement."3.76Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction. ( Binkley, P; Donnally, MR; Evanchan, J; Mazzaferri, E, 2010)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brendel, K1
Weigel, G1
Griesmacher, A1
Pachinger, O1
Mair, J1
Allen, MJ1
McLean-Veysey, P1
Evanchan, J1
Donnally, MR1
Binkley, P1
Mazzaferri, E1
Fontes-Carvalho, R1
Albuquerque, A1
Araújo, C1
Pimentel-Nunes, P1
Ribeiro, VG1
Alexopoulos, D1
Xanthopoulou, I1
Tsigkas, G1
Damelou, A1
Theodoropoulos, KC1
Kassimis, G1
Chouchoulis, K1
Davlouros, P1
Chiladakis, J1
Hahalis, G1
Parri, MS1
Gianetti, J1
Dushpanova, A1
Della Pina, F1
Saracini, C1
Marcucci, R1
Giusti, B1
Berti, S1
Mao, XB1
Wang, SQ1
Mao, Y1
Mahabaleshwarkar, RK1
Yang, Y1
Datar, MV1
Bentley, JP1
Strum, MW1
Banahan, BF1
Null, KD1

Trials

4 trials available for pantoprazole and Cardiovascular Stroke

ArticleYear
Omeprazole, but not pantoprazole, reduces the antiplatelet effect of clopidogrel: a randomized clinical crossover trial in patients after myocardial infarction evaluating the clopidogrel-PPIs drug interaction.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Blood Platelets; Clopidogrel; Cross-Over Studies; Dru

2011
Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Blood Platelets; Clopidogrel; Female; Humans; Male; M

2012
Pantoprazole significantly interferes with antiplatelet effect of clopidogrel: results of a pilot randomized trial.
    International journal of cardiology, 2013, Sep-01, Volume: 167, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Clopidogrel; Drug Interactions; Female; Humans; Male;

2013
[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2012, Volume: 32, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Endotoxins; Female; Glutamine; Heart Failure; Humans;

2012

Other Studies

4 other studies available for pantoprazole and Cardiovascular Stroke

ArticleYear
Low prevalence of clopidogrel and acetylsalicylic acid resistance in patients with acute myocardial infarction and pantoprazole treatment in everyday practice.
    International journal of cardiology, 2013, Sep-20, Volume: 168, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug

2013
Interaction between clopidogrel and proton pump inhibitors.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2009, Jun-09, Volume: 180, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Case-Control Studies; Clopidogrel; Drug Interactions; Drug

2009
Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction.
    Clinical cardiology, 2010, Volume: 33, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Angioplasty, Balloon, Coronary; Anti-Ulcer Agents; Clopidog

2010
Risk of adverse cardiovascular outcomes and all-cause mortality associated with concomitant use of clopidogrel and proton pump inhibitors in elderly patients.
    Current medical research and opinion, 2013, Volume: 29, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Case-Control Studies; Clopidogrel;

2013