Page last updated: 2024-11-02

pantoprazole and Acute Coronary Syndrome

pantoprazole has been researched along with Acute Coronary Syndrome in 7 studies

Pantoprazole: 2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.
pantoprazole : A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Co-administration of pantoprazole may enhance the antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome undergoing PCI."9.14Pantoprazole may enhance antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome. ( Bielis, L; Boinska, J; Budzyński, J; Kasprzak, M; Koziński, M; Kubica, J; Marciniak, A; Plazuk, W; Rość, D; Siller-Matula, J, 2009)
"This study sought to compare the effect of 2 proton pump inhibitors (PPIs) on platelet response to clopidogrel after coronary stenting for non-ST-segment elevation acute coronary syndrome (NSTE ACS)."5.14Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study. ( Alessi, MC; Bali, L; Bonnet, JL; Brissy, O; Cuisset, T; Frere, C; Gaborit, B; Morange, PE; Poyet, R; Quilici, J, 2009)
"Co-administration of pantoprazole may enhance the antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome undergoing PCI."5.14Pantoprazole may enhance antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome. ( Bielis, L; Boinska, J; Budzyński, J; Kasprzak, M; Koziński, M; Kubica, J; Marciniak, A; Plazuk, W; Rość, D; Siller-Matula, J, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, YJ1
Kim, N1
Jang, IJ1
Cho, JY1
Nam, RH1
Park, JH1
Jo, HJ1
Yoon, H1
Shin, CM1
Park, YS1
Lee, DH1
Jung, HC1
Juurlink, D1
Yao, DK1
Chen, H1
Wang, L1
Li, HW1
Wang, LX1
Cuisset, T1
Frere, C1
Quilici, J1
Poyet, R1
Gaborit, B1
Bali, L1
Brissy, O1
Morange, PE1
Alessi, MC1
Bonnet, JL1
Kasprzak, M1
Koziński, M1
Bielis, L1
Boinska, J1
Plazuk, W1
Marciniak, A1
Budzyński, J1
Siller-Matula, J1
Rość, D1
Kubica, J1
Wu, H1
Jing, Q1
Wang, J1
Guo, X1
Canpolat, U1
Şahiner, L1
Aytemir, K1
Oto, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02733640]42 participants (Actual)Interventional2012-10-31Completed
The Effect of Ticagrelor on Acute Coronary Syndrome Patients With Clopidogrel Resistance Undergoing Percutaneous Coronary Intervention[NCT01812330]Phase 3180 participants (Anticipated)Interventional2013-01-31Recruiting
Institute of Emergency and Critical Care Medicine , School of Yang-Ming University[NCT01588886]9,000 participants (Actual)Observational2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for pantoprazole and Acute Coronary Syndrome

ArticleYear
Pantoprazole Does Not Reduce the Antiplatelet Effect of Clopidogrel: A Randomized Controlled Trial in Korea.
    Gut and liver, 2017, Jul-15, Volume: 11, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Aged; Clopidogrel; Cytochrome P-45

2017
Comparison of Intravenous plus Oral Pantoprazole Therapy and Oral Pantoprazole Alone for Preventing Gastrointestinal Bleeding in Acute Coronary Syndrome Patients with High Bleeding Risk.
    Heart, lung & circulation, 2015, Volume: 24, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Administration, Intravenous; Admin

2015
Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study.
    Journal of the American College of Cardiology, 2009, Sep-22, Volume: 54, Issue:13

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Corona

2009
Pantoprazole may enhance antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome.
    Cardiology journal, 2009, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Corona

2009
Pantoprazole for the prevention of gastrointestinal bleeding in high-risk patients with acute coronary syndromes.
    Journal of critical care, 2011, Volume: 26, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Age Factors; Aged; Anticoagulants;

2011

Other Studies

2 other studies available for pantoprazole and Acute Coronary Syndrome

ArticleYear
Clopidogrel and proton pump inhibitors.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014, Feb-18, Volume: 186, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Clinical Trials as Topic; Clopidog

2014
Allergic reaction to proton pump ınhibitor: pantoprazole induced Kounis syndrome.
    International journal of cardiology, 2012, Aug-23, Volume: 159, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Adult; Drug Hypersensitivity; Huma

2012