panobinostat and Arthritis--Rheumatoid

panobinostat has been researched along with Arthritis--Rheumatoid* in 1 studies

Other Studies

1 other study(ies) available for panobinostat and Arthritis--Rheumatoid

Article	Year
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8 Epigenetic modifiers of the histone deacetylase (HDAC) family contribute to autoimmunity, cancer, HIV infection, inflammation, and neurodegeneration. Hence, histone deacetylase inhibitors (HDACi), which alter protein acetylation, gene expression patterns, and cell fate decisions, represent promising new drugs for the therapy of these diseases. Whereas pan-HDACi inhibit all 11 Zn Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Binding Sites; Carbolines; Cell Line, Tumor; Collagen Type II; HEK293 Cells; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Mice, Inbred DBA; Molecular Docking Simulation; Zebrafish	2018

Article

Year

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.

Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8

Epigenetic modifiers of the histone deacetylase (HDAC) family contribute to autoimmunity, cancer, HIV infection, inflammation, and neurodegeneration. Hence, histone deacetylase inhibitors (HDACi), which alter protein acetylation, gene expression patterns, and cell fate decisions, represent promising new drugs for the therapy of these diseases. Whereas pan-HDACi inhibit all 11 Zn

Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Binding Sites; Carbolines; Cell Line, Tumor; Collagen Type II; HEK293 Cells; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Mice, Inbred DBA; Molecular Docking Simulation; Zebrafish

2018