pancuronium and Neuroleptic-Malignant-Syndrome

Neuroleptic malignant syndrome is an idiosyncratic reaction associated with the use of neuroleptic drugs. We report a case of this rare syndrome in a head injury patient associated with some unusual features: rhabdomyolysis with a high level of creatine kinase, the development of acute renal failure, the early use of continuous venovenous haemofiltration in treatment and rigidity that was refractory to conventional treatment with dantrolene and bromocriptine. The diagnosis in patients with multiple injuries must be based on a high index of suspicion.

Topics: Adolescent; Bromocriptine; Craniocerebral Trauma; Creatine Kinase; Dantrolene; Hemofiltration; Humans; Male; Multiple Trauma; Neuroleptic Malignant Syndrome; Pancuronium; Rhabdomyolysis

Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Electroconvulsive Therapy; Humans; Male; Malignant Hyperthermia; Neuroleptic Malignant Syndrome; Pancuronium; Thiopental

Topics: Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Pancuronium