pancuronium and Eye-Injuries

Topics: Adult; Atracurium; Emergencies; Eye Injuries; Humans; Intraocular Pressure; Isoquinolines; Neuromuscular Blocking Agents; Pancuronium; Vecuronium Bromide

The effects of atracurium on intraocular pressure (IOP) were compared with those of pancuronium in 20 patients less than 45 years-of-age requiring surgery for trauma of one eye. After a standard premedication and the application of topical analgesia to the upper airway, anaesthesia was induced with thiopentone i.v. and the trachea was intubated without the use of neuromuscular blockade. Following 20 min of steady state anaesthesia during which measurements of IOP, arterial pressure, heart rate, FIO2, FE'CO2 and CVP were recorded, one group of patients received atracurium 0.45 mg kg-1 and the other pancuronium 0.1 mg kg-1. The observations were repeated for a further 15 min before surgery commenced. Neither atracurium nor pancuronium produced any change in IOP. Atracurium was associated with greater cardiovascular stability than pancuronium.

Topics: Adolescent; Adult; Anesthesia, General; Atracurium; Blood Pressure; Carbon Dioxide; Eye Injuries; Heart Rate; Humans; Intraocular Pressure; Isoquinolines; Neuromuscular Blocking Agents; Pancuronium

Intraocular pressure remained stable when either pancuronium or alcuronium was used to produce muscle relaxation, suggesting that alcuronium may be a reasonable alternative to pancuronium for routine surgery of the open eye, particularly in elderly patients with limited cardiac reserve.

Topics: Adolescent; Adult; Alcuronium; Blood Pressure; Central Venous Pressure; Eye Injuries; Heart Rate; Humans; Intraocular Pressure; Male; Pancuronium; Toxiferine

Topics: Drug Interactions; Eye Injuries; Gentamicins; Humans; Intubation, Intratracheal; Male; Middle Aged; Neuromuscular Blocking Agents; Pancuronium; Pneumonia, Aspiration; Time Factors; Vecuronium Bromide

Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Child; Child, Preschool; Eye Foreign Bodies; Eye Injuries; Humans; Intraocular Pressure; Intubation, Intratracheal; Middle Aged; Pancuronium; Postoperative Complications; Retrospective Studies; Succinylcholine; Tubocurarine; Wounds, Penetrating