pancuronium has been researched along with Eye-Diseases* in 2 studies
1 trial(s) available for pancuronium and Eye-Diseases
| Article | Year |
|---|---|
Circulatory drugs modify the hemodynamic actions of alfentanil combined with vecuronium or pancuronium.
To verify, whether drugs used to treat hypertension, coronary disease, and heart insufficiency modify the hemodynamic effects of the combinations alfentanil-vecuronium and alfentanil-pancuronium, 36 patients taking these drugs (most often beta-adrenergic antagonists) were randomized to receive either vecuronium or pancuronium in connection with ophthalmic surgery. In comparison with healthy patients, the heart rate and arterial pressure changes during induction, intubation and surgery appeared to be smoothed. Heart rate and arterial pressure equaled between the study groups, indicating a block of the sympathomimetic actions of pancuronium. One third of the patients receiving vecuronium exhibited nodal rhythm and some of them showed slow heart rates during intense surgical stimulation. Pancuronium offered protection against bradyarrhythmias. Topics: Aged; Alfentanil; Blood Pressure; Cardiovascular Agents; Drug Interactions; Eye Diseases; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Pancuronium; Vecuronium Bromide | 1994 |
1 other study(ies) available for pancuronium and Eye-Diseases
| Article | Year |
|---|---|
Alfentanil combined with vecuronium or pancuronium for use in eye surgery.
The usefulness of alfentanil for eye surgery, when combined with either vecuronium or pancuronium, was evaluated in 44 fit anticholinergized patients. Following thiopentone, four min after the administration of the relaxant (0.1 mg/kg), and two min after the administration of alfentanil (15 micrograms/kg), a sixth of the patients bucked on introducing the endotracheal tube. The anesthesia for cataract extraction was maintained using alfentanil-relaxant-N2O in 18 patients. In 16 of them, a low dose alfentanil regimen, occasionally supplemented with thiopentone, was satisfactory, and the recovery of alertness was rapid. In 26 patients, alfentanil, 25 micrograms/kg, supplemented with isoflurane, efficiently obtunded the hemodynamic response after traction of extrinsic eye muscles at the commencement of major surgery. The patients receiving vecuronium presented with lower heart rates, than did those receiving pancuronium (P < 0.05). During major operations, nodal rhythm was more frequent in the vecuronium group, than in the pancuronium group (P < 0.0001). Topics: Aged; Alfentanil; Anesthesia Recovery Period; Cataract Extraction; Eye Diseases; Female; Hemodynamics; Humans; Intubation, Intratracheal; Male; Middle Aged; Pancuronium; Vecuronium Bromide | 1992 |