pamidronate has been researched along with Spondylitis, Ankylosing in 23 studies
Spondylitis, Ankylosing: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pamidronate at 60 mg was compared with pamidronate at 10 mg rather than placebo in view of the high incidence of transient arthralgias upon first IV exposure to the drug." | 5.10 | A six-month randomized, controlled, double-blind, dose-response comparison of intravenous pamidronate (60 mg versus 10 mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis. ( Aaron, SL; Chiu, P; Davis, P; Fitzgerald, AA; Homik, J; Jhangri, GS; LeClercq, S; Maksymowych, WP; Russell, AS; Sholter, D; Skeith, KJ; Yan, A, 2002) |
| " Examination of the responsiveness of the individual components of the BASMI revealed significance for lumbar side flexion in the 60 mg dosing group (ES = 0." | 2.71 | Clinimetric evaluation of the bath ankylosing spondylitis metrology index in a controlled trial of pamidronate therapy. ( Conner-Spady, B; Jauregui, E; Maksymowych, WP; Russell, AS, 2004) |
| "Pamidronate (60 mg) was given intravenously on Days 1, 2, 14, 28, and 56, over 4 h in 500 ml of 5% dextrose." | 2.70 | Clinical and radiological amelioration of refractory peripheral spondyloarthritis by pulse intravenous pamidronate therapy. ( Aaron, S; Chiu, P; Jhangri, GS; Lambert, R; Leclercq, S; Maksymowych, WP; Russell, AS; Wong, B, 2001) |
| "Ankylosing spondylitis is an inflammatory disorder affecting the axial skeleton and periphery." | 2.42 | The treatment of ankylosing spondylitis. ( Davis, JC; Scalapino, KJ, 2003) |
| "A FREQUENT AFFECTION: Ankylosing spondylitis is a chronic inflammatory rheumatism usually affecting young adults and characterized by an inflammatory enthesiopathy progressing towards ossification and ankylosis." | 2.42 | [Ankylosing spondylitis]. ( El Maghraoui, A, 2004) |
| "Management of ankylosing spondylitis (AS) is challenged by the progressive nature of the disease." | 2.41 | Conventional treatments for ankylosing spondylitis. ( Brandt, J; Dijkmans, B; Dougados, M; Khan, M; Maksymowych, W; van der Linden, S, 2002) |
| " In addition, the long-term use (efficacy and tolerability) of these two agents deserves attention." | 2.41 | Therapeutic advances in ankylosing spondylitis. ( Toussirot, E; Wendling, D, 2001) |
| "A patient with ankylosing spondylitis, after demonstrating incomplete clinical response to adalimumab, received three monthly infusions of pamidronate along with continuing TNF-alpha blockade." | 1.36 | The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis. ( Boulman, N; Odeh, M; Rimar, D; Rosner, I; Rozenbaum, M; Slobodin, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 19 (82.61) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goh, L | 1 |
| Samanta, A | 1 |
| Slobodin, G | 1 |
| Rosner, I | 1 |
| Rimar, D | 1 |
| Boulman, N | 1 |
| Rozenbaum, M | 1 |
| Odeh, M | 1 |
| Santra, G | 1 |
| Sarkar, RN | 1 |
| Phaujdar, S | 1 |
| Banerjee, S | 1 |
| Siddhanta, S | 1 |
| De Langhe, E | 1 |
| Lories, R | 1 |
| Maenaut, K | 1 |
| De Vlam, K | 1 |
| Dougados, M | 2 |
| Dijkmans, B | 1 |
| Khan, M | 1 |
| Maksymowych, W | 2 |
| van der Linden, S | 1 |
| Brandt, J | 2 |
| Toussirot, E | 2 |
| Wendling, D | 2 |
| Singh, R | 1 |
| Menon, Y | 1 |
| Cuchacovich, R | 1 |
| Espinoza, LR | 1 |
| Scalapino, KJ | 1 |
| Davis, JC | 2 |
| Haibel, H | 1 |
| Rudwaleit, M | 1 |
| Soerensen, H | 1 |
| Sieper, J | 1 |
| Braun, J | 1 |
| Huang, F | 1 |
| Cairns, AP | 1 |
| Wright, SA | 1 |
| Taggart, AJ | 1 |
| Coward, SM | 1 |
| Wright, GD | 1 |
| Jauregui, E | 2 |
| Conner-Spady, B | 2 |
| Russell, AS | 5 |
| Maksymowych, WP | 5 |
| El Maghraoui, A | 1 |
| Akerkar, SM | 1 |
| Bichile, LS | 1 |
| Boulos, P | 1 |
| Macleod, SM | 1 |
| Hunsche, E | 1 |
| Grover, R | 1 |
| Shankar, S | 1 |
| Aneja, R | 1 |
| Marwaha, V | 1 |
| Gupta, R | 1 |
| Kumar, A | 1 |
| Mallon, C | 1 |
| Richardson, R | 1 |
| Chung, C | 1 |
| Zappala, L | 1 |
| Pile, K | 1 |
| Malaviya, AN | 1 |
| Kapoor, S | 1 |
| Garg, S | 1 |
| Ahmad, I | 1 |
| Raja, RR | 1 |
| Chogle, AR | 1 |
| Mishra, H | 1 |
| Chakravarty, A | 1 |
| Jhangri, GS | 3 |
| Leclercq, S | 3 |
| Skeith, K | 1 |
| Yan, A | 2 |
| Lambert, R | 1 |
| Chiu, P | 2 |
| Wong, B | 1 |
| Aaron, S | 1 |
| Fitzgerald, AA | 1 |
| Skeith, KJ | 1 |
| Aaron, SL | 1 |
| Homik, J | 1 |
| Davis, P | 1 |
| Sholter, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined Treatment With TNF (Tumor Necrosis Factor) Inhibitor and Pamidronate in AS Patients: Effect on the Radiographic Progression[NCT02313727] | Phase 4 | 30 participants (Anticipated) | Interventional | 2014-12-31 | Not yet recruiting | ||
| Anti-Tumor Necrosis Factor (TNFR:Fc) in Ankylosing Spondylitis[NCT00000433] | Phase 2 | 42 participants | Interventional | 1999-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for pamidronate and Spondylitis, Ankylosing
| Article | Year |
|---|---|
A systematic MEDLINE analysis of therapeutic approaches in ankylosing spondylitis.
Topics: Adalimumab; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclona | 2009 |
Conventional treatments for ankylosing spondylitis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Azathioprine; Dipho | 2002 |
Recent progress in ankylosing spondylitis treatment.
Topics: Celecoxib; Controlled Clinical Trials as Topic; Diphosphonates; Drug Therapy; Humans; Methotrexate; | 2003 |
The treatment of ankylosing spondylitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antirheumatic Ag | 2003 |
New therapies for ankylosing spondylitis: etanercept, thalidomide, and pamidronate.
Topics: Anti-Inflammatory Agents; Diphosphonates; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Ag | 2003 |
[Ankylosing spondylitis].
Topics: Acquired Hyperostosis Syndrome; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2004 |
Pamidronate--a promising new candidate for the management of spondyloarthropathy.
Topics: Anti-Inflammatory Agents; Diphosphonates; Humans; Pamidronate; Spondylitis, Ankylosing | 2005 |
Pharmacological treatment of ankylosing spondylitis: a systematic review.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical | 2005 |
Therapeutic advances in ankylosing spondylitis.
Topics: Cyclooxygenase Inhibitors; Diphosphonates; Humans; Methotrexate; Pamidronate; Spondylitis, Ankylosin | 2001 |
7 trials available for pamidronate and Spondylitis, Ankylosing
| Article | Year |
|---|---|
An open study of pulse pamidronate treatment in severe ankylosing spondylitis, and its effect on biochemical markers of bone turnover.
Topics: Adult; Anti-Inflammatory Agents; Bone Remodeling; Collagen; Diphosphonates; Female; Humans; Male; Mi | 2005 |
Clinimetric evaluation of the bath ankylosing spondylitis metrology index in a controlled trial of pamidronate therapy.
Topics: Adult; Aged; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administrat | 2004 |
Treatment of ankylosing spondylitis with pamidronate: an open label study.
Topics: Adult; Anti-Inflammatory Agents; Diphosphonates; Female; Humans; Male; Pamidronate; Severity of Illn | 2006 |
A new strategy of drug treatment in NSAID-unresponsive ankylosing spondylitis: combination of pamidronate and methylprednisolone monthly intravenous infusions on the background of a combination of disease modifying drugs sulfasalazine and methotrexate.
Topics: Adolescent; Adult; Antirheumatic Agents; Bone Density Conservation Agents; Diphosphonates; Drug Resi | 2007 |
An open study of pamidronate in the treatment of refractory ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents; Blood Sedimentation; Diphosphonates; Female; Humans; Male; Middle A | 1998 |
Clinical and radiological amelioration of refractory peripheral spondyloarthritis by pulse intravenous pamidronate therapy.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Reactive; Blood Sedimentation; Bone Marrow; C-Reactive P | 2001 |
A six-month randomized, controlled, double-blind, dose-response comparison of intravenous pamidronate (60 mg versus 10 mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diphosphonates | 2002 |
7 other studies available for pamidronate and Spondylitis, Ankylosing
| Article | Year |
|---|---|
The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis.
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dip | 2010 |
Assessment of the efficacy of pamidronate in ankylosing spondylitis: an open prospective trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Sediment | 2010 |
The kaleidoscopic presentation of the spondyloarthritis concept in a female patient.
Topics: Acne Vulgaris; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arthritis; Arthritis, Reacti | 2011 |
A six-month randomized, controlled, double-blind, dose-response comparison of intravenous pamidronate (60 mg versus 10 mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis: comment on the article by Maksymowych et a
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diphosphonates; Double-Bli | 2003 |
Treatment of active ankylosing spondylitis with pamidronate.
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Diphosphonates; Female; Follow-Up Studies; Hum | 2003 |
Development and validation of the Edmonton Ankylosing Spondylitis Metrology Index.
Topics: Adult; Diphosphonates; Female; Hip Joint; Humans; Male; Observer Variation; Pamidronate; Radiography | 2006 |
A new strategy of drug treatment in NSAID--unresponsive ankylosing spondylitis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; | 2007 |