Page last updated: 2024-11-02

pamidronate and Spinal Fractures

pamidronate has been researched along with Spinal Fractures in 34 studies

Spinal Fractures: Broken bones in the vertebral column.

Research Excerpts

ExcerptRelevanceReference
" In this study, we evaluated whether intravenous pamidronate can prevent bone loss and reduce vertebral fractures in patients with malignant lymphoma who were receiving chemotherapy."9.11Effect of pamidronate on new vertebral fractures and bone mineral density in patients with malignant lymphoma receiving chemotherapy. ( Hahn, JS; Kim, SH; Lim, SK, 2004)
"The effect of pamidronate therapy on bone histology was studied in patients with osteoporosis with at least one vertebral fracture in a randomized, double-masked, placebo-controlled, multi-center trial."9.09Bone histomorphometric evaluation of pamidronate treatment in clinically manifest osteoporosis. ( Bravenboer, N; Hamdy, NA; Holzmann, P; Lips, P; Netelenbos, JC; Papapoulos, SE, 1999)
"To determine the efficacy and safety of 21 monthly cycles of pamidronate therapy in patients with advanced multiple myeloma."9.08Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. ( Ballester, O; Bell, R; Berenson, JR; Blacklock, H; Bordoni, R; Dimopoulos, MA; George, S; Heffernan, M; Keller, A; Knight, RD; Kovacs, M; Lichtenstein, A; Lipton, A; Porter, L; Reitsma, DJ; Seaman, J; Simeone, JF, 1998)
" Here, a case of a 9-year-old girl with familial HCS and multiple spinal fractures, who has been effectively treated with pamidronate, is presented."7.78Two-year cyclic infusion of pamidronate improves bone mass density and eliminates risk of fractures in a girl with osteoporosis due to Hajdu-Cheney syndrome. ( Galli-Tsinopoulou, A; Giannopoulou, EZ; Giza, S; Kyrgios, I; Laliotis, N; Maggana, I, 2012)
" To assess the role of biochemical bone markers in classification of children with osteogenesis imperfecta (OI), their possible association with vertebral compression fractures in milder forms of OI and their role in monitoring of intravenous pamidronate (APD) treatment."7.76Biochemical bone markers in the assessment and pamidronate treatment of children and adolescents with osteogenesis imperfecta. ( Aström, E; Eksborg, S; Magnusson, P; Söderhäll, S, 2010)
"To investigate the use of the aminobisphosphonate, disodium pamidronate, in children with vertebral osteoporosis."7.70Intravenous pamidronate in juvenile osteoporosis. ( Boivin, CM; Crabtree, NJ; Shaw, NJ, 2000)
"Pamidronate, a bisphosphonate analogue has been evaluated in a retrospective study for its analgesic effect on chronic back pain due to vertebral fractures in 26 patients suffering from senile osteoporosis or glucocorticoid-induced osteoporosis."7.70Analgesic effect of intravenous pamidronate on chronic back pain due to osteoporotic vertebral fractures. ( Appelboom, T; Gangji, V, 1999)
"We discuss this approach of treating osteoporosis with corticoids and immunosuppressors according to the present knowledge of bone biology."5.31[Vertebral osteoporosis induced by corticoids and cyclosporine ina a patient with Still disease]. ( Fassi, J; Plantalech, L, 2001)
"Our aim was to compare the analgesic efficacy of pamidronate (PAM) and synthetic human calcitonin (CT) in intravenous infusion for recent painful benign vertebral compression in a randomised prospective double-blind study."5.12Comparison of the analgesic efficacy of pamidronate and synthetic human calcitonin in osteoporotic vertebral fractures: a double-blind controlled study. ( Cantagrel, A; Cantogrel, S; Constantin, A; Jamard, B; Laroche, M; Mazières, B; Zabraniecki, L, 2006)
"We performed a randomized, double-blind, controlled clinical trial comparing intravenous pamidronate and placebo for pain relief in recent osteoporotic vertebral compression fractures (VCF)."5.12Intravenous pamidronate for pain relief in recent osteoporotic vertebral compression fracture: a randomized double-blind controlled study. ( Armingeat, T; Brondino, R; Lafforgue, P; Legré, V; Pham, T, 2006)
" In this study, we evaluated whether intravenous pamidronate can prevent bone loss and reduce vertebral fractures in patients with malignant lymphoma who were receiving chemotherapy."5.11Effect of pamidronate on new vertebral fractures and bone mineral density in patients with malignant lymphoma receiving chemotherapy. ( Hahn, JS; Kim, SH; Lim, SK, 2004)
"The effect of pamidronate therapy on bone histology was studied in patients with osteoporosis with at least one vertebral fracture in a randomized, double-masked, placebo-controlled, multi-center trial."5.09Bone histomorphometric evaluation of pamidronate treatment in clinically manifest osteoporosis. ( Bravenboer, N; Hamdy, NA; Holzmann, P; Lips, P; Netelenbos, JC; Papapoulos, SE, 1999)
"To determine the efficacy and safety of 21 monthly cycles of pamidronate therapy in patients with advanced multiple myeloma."5.08Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. ( Ballester, O; Bell, R; Berenson, JR; Blacklock, H; Bordoni, R; Dimopoulos, MA; George, S; Heffernan, M; Keller, A; Knight, RD; Kovacs, M; Lichtenstein, A; Lipton, A; Porter, L; Reitsma, DJ; Seaman, J; Simeone, JF, 1998)
" Here, a case of a 9-year-old girl with familial HCS and multiple spinal fractures, who has been effectively treated with pamidronate, is presented."3.78Two-year cyclic infusion of pamidronate improves bone mass density and eliminates risk of fractures in a girl with osteoporosis due to Hajdu-Cheney syndrome. ( Galli-Tsinopoulou, A; Giannopoulou, EZ; Giza, S; Kyrgios, I; Laliotis, N; Maggana, I, 2012)
" To assess the role of biochemical bone markers in classification of children with osteogenesis imperfecta (OI), their possible association with vertebral compression fractures in milder forms of OI and their role in monitoring of intravenous pamidronate (APD) treatment."3.76Biochemical bone markers in the assessment and pamidronate treatment of children and adolescents with osteogenesis imperfecta. ( Aström, E; Eksborg, S; Magnusson, P; Söderhäll, S, 2010)
"Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget's disease."3.70Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease. ( MacGowan, JR; Morris, VH; Pringle, J; Stamp, TC, 2000)
"To investigate the use of the aminobisphosphonate, disodium pamidronate, in children with vertebral osteoporosis."3.70Intravenous pamidronate in juvenile osteoporosis. ( Boivin, CM; Crabtree, NJ; Shaw, NJ, 2000)
"Pamidronate, a bisphosphonate analogue has been evaluated in a retrospective study for its analgesic effect on chronic back pain due to vertebral fractures in 26 patients suffering from senile osteoporosis or glucocorticoid-induced osteoporosis."3.70Analgesic effect of intravenous pamidronate on chronic back pain due to osteoporotic vertebral fractures. ( Appelboom, T; Gangji, V, 1999)
"Osteoporosis is a disorder of bone mineralisation occurring in about one third of adults with cystic fibrosis."3.01Bisphosphonates for osteoporosis in people with cystic fibrosis. ( Chang, AB; Conwell, LS; Jeffery, TC, 2023)
"Pamidronate treatment was associated with development of adynamic bone histology."2.71Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate. ( Bognar, I; Burris, L; Coco, M; Durkin, P; Faugere, MC; Figueroa, K; Glicklich, D; Greenstein, S; Malluche, H; McDonough, P; Schechner, R; Tellis, V; Wang, G, 2003)
"We discuss this approach of treating osteoporosis with corticoids and immunosuppressors according to the present knowledge of bone biology."1.31[Vertebral osteoporosis induced by corticoids and cyclosporine ina a patient with Still disease]. ( Fassi, J; Plantalech, L, 2001)
"Osteoporosis is common in patients with chronic cholestatic liver disease, and atraumatic spinal fracture is a recognized complication after orthotopic liver transplantation."1.30Intravenous bisphosphonate prevents symptomatic osteoporotic vertebral collapse in patients after liver transplantation. ( Day, CP; Francis, RM; Hudson, M; Manas, DM; Reeves, HL, 1998)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (23.53)18.2507
2000's19 (55.88)29.6817
2010's6 (17.65)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Jeffery, TC1
Chang, AB1
Conwell, LS1
Mhaskar, R1
Kumar, A1
Miladinovic, B1
Djulbegovic, B1
Wang, Z1
Han, Z1
Tao, J1
Lu, P1
Liu, X1
Wang, J1
Wu, B1
Huang, Z1
Yin, C1
Tan, R1
Gu, M1
Singh, A1
Schaeffer, EK1
Reilly, CW1
Aström, E1
Magnusson, P1
Eksborg, S1
Söderhäll, S1
Jenkinson, E1
Galli-Tsinopoulou, A1
Kyrgios, I1
Giza, S1
Giannopoulou, EZ1
Maggana, I1
Laliotis, N1
Heijckmann, AC1
Juttmann, JR1
Wolffenbuttel, BH1
Pappagallo, M1
Breuer, B1
Schneider, A1
Sperber, K1
Coco, M1
Glicklich, D1
Faugere, MC1
Burris, L1
Bognar, I1
Durkin, P1
Tellis, V1
Greenstein, S1
Schechner, R1
Figueroa, K1
McDonough, P1
Wang, G1
Malluche, H1
Kim, SH1
Lim, SK1
Hahn, JS1
Laroche, M2
Cantogrel, S1
Jamard, B1
Constantin, A1
Zabraniecki, L1
Cantagrel, A1
Mazières, B2
Boot, AM1
de Coo, RF1
Pals, G1
de Muinck Keizer-Schrama, SM1
Armingeat, T1
Brondino, R1
Pham, T1
Legré, V1
Lafforgue, P1
Bret, J1
Brouchet, A1
Lucarelli, S1
Borrelli, O1
Paganelli, M1
Capocaccia, P1
Frediani, T1
Ferri, F1
Cucchiara, S1
Ward, KA1
Adams, JE1
Freemont, TJ1
Mughal, MZ1
Muschitz, C1
Roschger, P1
Patsch, J1
Pollhammer, I1
Koller, B1
Klaushofer, K1
Resch, H1
Gleeson, H1
Wiltshire, E1
Briody, J1
Hall, J1
Chaitow, J1
Sillence, D1
Cowell, C1
Munns, C1
Reid, IR1
Wattie, DJ1
Evans, MC1
Gamble, GD1
Stapleton, JP1
Cornish, J1
Landman, JO1
Hamdy, NA2
Pauwels, EK1
Papapoulos, SE3
Berenson, JR1
Lichtenstein, A1
Porter, L1
Dimopoulos, MA1
Bordoni, R1
George, S1
Lipton, A1
Keller, A1
Ballester, O1
Kovacs, M1
Blacklock, H1
Bell, R1
Simeone, JF1
Reitsma, DJ1
Heffernan, M1
Seaman, J1
Knight, RD1
Man, Z1
Otero, AB1
Seymour, JF1
Reeves, HL1
Francis, RM1
Manas, DM1
Hudson, M1
Day, CP1
Bravenboer, N1
Holzmann, P1
Netelenbos, JC1
Lips, P1
Abdulla, AJ1
MacGowan, JR1
Pringle, J1
Morris, VH1
Stamp, TC1
Shaw, NJ1
Boivin, CM1
Crabtree, NJ1
Gangji, V1
Appelboom, T1
Fassi, J1
Plantalech, L1
Geusens, P1
Menten, J1
Vosse, D1
Vanhoof, J1
van der Linden, S1
Ninkovic, M1
Love, S1
Tom, BD1
Bearcroft, PW1
Alexander, GJ1
Compston, JE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation[NCT02074631]Phase 280 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for pamidronate and Spinal Fractures

ArticleYear
Bisphosphonates for osteoporosis in people with cystic fibrosis.
    The Cochrane database of systematic reviews, 2023, 01-10, Volume: 1

    Topics: Adult; Alendronate; Bone Density Conservation Agents; Child; Cystic Fibrosis; Diphosphonates; Female

2023
Bisphosphonates in multiple myeloma: an updated network meta-analysis.
    The Cochrane database of systematic reviews, 2017, 12-18, Volume: 12

    Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonat

2017
Clinical efficacy and safety of pamidronate therapy on bone mass density in early post-renal transplant period: a meta-analysis of randomized controlled trials.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Absorptiometry, Photon; Bone Density; Bone Density Conservation Agents; Diphosphonates; Humans; Immu

2014
Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1: do bisphosphonates relieve pain caused by acute osteoporotic vertebral compression fractures?
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:3

    Topics: Administration, Oral; Aged; Back Pain; Bone Density Conservation Agents; Diphosphonates; Female; Fra

2011
Bisphosphonates in the treatment of osteoporosis. Principles and efficacy.
    Annales de medecine interne, 2000, Volume: 151, Issue:6

    Topics: Administration, Oral; Alendronate; Animals; Bone and Bones; Bone Density; Calcium Channel Blockers;

2000

Trials

8 trials available for pamidronate and Spinal Fractures

ArticleYear
Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Biopsy; Bone Density; Diphosphonates; Female; Hormones; Humans; Imm

2003
Effect of pamidronate on new vertebral fractures and bone mineral density in patients with malignant lymphoma receiving chemotherapy.
    The American journal of medicine, 2004, Apr-15, Volume: 116, Issue:8

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Bone Density; Diphosphonates; Female; Humans; Lymph

2004
Comparison of the analgesic efficacy of pamidronate and synthetic human calcitonin in osteoporotic vertebral fractures: a double-blind controlled study.
    Clinical rheumatology, 2006, Volume: 25, Issue:5

    Topics: Aged; Aged, 80 and over; Analgesics; Bone Density Conservation Agents; Calcitonin; Diphosphonates; F

2006
Intravenous pamidronate for pain relief in recent osteoporotic vertebral compression fracture: a randomized double-blind controlled study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006, Volume: 17, Issue:11

    Topics: Acute Disease; Aged; Aged, 80 and over; Analgesics; Back Pain; Bone Density Conservation Agents; Dip

2006
Continuous therapy with pamidronate, a potent bisphosphonate, in postmenopausal osteoporosis.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:6

    Topics: Aged; Alkaline Phosphatase; Bone Density; Calcium; Diphosphonates; Double-Blind Method; Female; Huma

1994
Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:2

    Topics: Diphosphonates; Double-Blind Method; Drug Administration Schedule; Female; Fractures, Spontaneous; H

1998
Bone histomorphometric evaluation of pamidronate treatment in clinically manifest osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 9, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bone and Bones; Bone Remodeling; Diphosphonates; Double-Blind

1999
Lack of effect of intravenous pamidronate on fracture incidence and bone mineral density after orthotopic liver transplantation.
    Journal of hepatology, 2002, Volume: 37, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Bone Density; Diphosphonates; Female; Humans; Incidence; Injections

2002

Other Studies

21 other studies available for pamidronate and Spinal Fractures

ArticleYear
Vertebral Fractures in Duchenne Muscular Dystrophy Patients Managed With Deflazacort.
    Journal of pediatric orthopedics, 2018, Volume: 38, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Bone Density; Bone Density Conservation Agents; Child; Diphosph

2018
Biochemical bone markers in the assessment and pamidronate treatment of children and adolescents with osteogenesis imperfecta.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:12

    Topics: Adolescent; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Density; Bone Density Conservation A

2010
Two-year cyclic infusion of pamidronate improves bone mass density and eliminates risk of fractures in a girl with osteoporosis due to Hajdu-Cheney syndrome.
    Minerva endocrinologica, 2012, Volume: 37, Issue:3

    Topics: Abnormalities, Multiple; Acro-Osteolysis; Bone Density; Bone Density Conservation Agents; Child; Dip

2012
Intravenous pamidronate compared with oral alendronate for the treatment of postmenopausal osteoporosis.
    The Netherlands journal of medicine, 2002, Volume: 60, Issue:8

    Topics: Administration, Oral; Aged; Alendronate; Bone Density; Diphosphonates; Female; Fractures, Spontaneou

2002
Treatment of chronic mechanical spinal pain with intravenous pamidronate: a review of medical records.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Back Pain; Chronic Disease; Diphosphonates

2003
Muscle weakness as presenting symptom of osteogenesis imperfecta.
    European journal of pediatrics, 2006, Volume: 165, Issue:6

    Topics: Bone Density Conservation Agents; Child, Preschool; Diphosphonates; Electromyography; Electrophoresi

2006
Clinical and densitometric efficacy of the association of interferon alpha and pamidronate in the treatment of osteoporosis in patients with systemic mastocytosis.
    Clinical rheumatology, 2007, Volume: 26, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bone Density; Bone Marrow Cells; Bone Remodeling; Diphosphona

2007
Vertebral fractures and increased sensitivity to corticosteroids in a child with ulcerative colitis: successful use of pamidronate.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 43, Issue:4

    Topics: Back Pain; Bone Density; Bone Density Conservation Agents; Child; Colitis, Ulcerative; Diphosphonate

2006
Can bisphosphonate treatment be stopped in a growing child with skeletal fragility?
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007, Volume: 18, Issue:8

    Topics: Accidental Falls; Bone Density; Bone Density Conservation Agents; Child, Preschool; Diphosphonates;

2007
High-dose bisphosphonate therapy in an urgent case of spontaneous multiple vertebral fractures in a 55 year old woman.
    Wiener medizinische Wochenschrift (1946), 2007, Volume: 157, Issue:15-16

    Topics: Absorptiometry, Photon; Accidental Falls; Administration, Oral; Biopsy; Bone and Bones; Bone Density

2007
Childhood chronic recurrent multifocal osteomyelitis: pamidronate therapy decreases pain and improves vertebral shape.
    The Journal of rheumatology, 2008, Volume: 35, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Bone Density; Child; Child, Preschool; Diphosphonates; Female;

2008
Skeletal metabolism in patients with osteoporosis after discontinuation of long-term treatment with oral pamidronate.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:12

    Topics: Administration, Oral; Bone and Bones; Bone Density; Diphosphonates; Female; Femur Neck; Follow-Up St

1995
[New spine and non-spine fractures in 871 women/year treated with oral pamidronate plus calcium and vitamin D supplements].
    Medicina, 1997, Volume: 57 Suppl 1

    Topics: Accidental Falls; Bone Density; Calcium, Dietary; Diphosphonates; Female; Follow-Up Studies; Fractur

1997
Long-term pamidronate in multiple myeloma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7

    Topics: Antineoplastic Agents; Diphosphonates; Female; Fractures, Spontaneous; Humans; Male; Multiple Myelom

1998
Intravenous bisphosphonate prevents symptomatic osteoporotic vertebral collapse in patients after liver transplantation.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1998, Volume: 4, Issue:5

    Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Diphosphonates; Female; Follow-Up Studies; Fractu

1998
Use of pamidronate for acute pain relief following osteoporotic vertebral fractures.
    Rheumatology (Oxford, England), 2000, Volume: 39, Issue:5

    Topics: Acute Disease; Aged; Aged, 80 and over; Analgesics; Diphosphonates; Female; Humans; Middle Aged; Ost

2000
Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease.
    Skeletal radiology, 2000, Volume: 29, Issue:5

    Topics: Aged; Alkaline Phosphatase; Anti-Inflammatory Agents; Arthralgia; Diphosphonates; Etidronic Acid; Fo

2000
Intravenous pamidronate in juvenile osteoporosis.
    Archives of disease in childhood, 2000, Volume: 83, Issue:2

    Topics: Absorptiometry, Photon; Acute-Phase Reaction; Adolescent; Bone Density; Child; Diphosphonates; Femal

2000
Analgesic effect of intravenous pamidronate on chronic back pain due to osteoporotic vertebral fractures.
    Clinical rheumatology, 1999, Volume: 18, Issue:3

    Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents; Back Pain; Diphosphonates; Female; Human

1999
[Vertebral osteoporosis induced by corticoids and cyclosporine ina a patient with Still disease].
    Medicina, 2001, Volume: 61, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Benzothiadiazines; Calcitonin; Cyclosporine; Diphosphonates; Diureti

2001
Recovery from severe glucocorticoid-induced osteoporosis in an adolescent boy.
    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2001,Winter, Volume: 4, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Body Height; Bone Density; Brain Stem Neoplasms; Diphosphonate

2001