pamidronate has been researched along with Scleritis in 6 studies
Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner." | 8.83 | Scleritis complicating zoledronic acid infusion. ( Badros, A; Benderson, D; Karakunnel, J; Kathuria, S, 2006) |
| "To evaluate reported cases of scleritis and other ocular side effects associated with pamidronate disodium, with emphasis on previously unreported cases of scleritis." | 7.72 | Scleritis and other ocular side effects associated with pamidronate disodium. ( Fraunfelder, FT; Fraunfelder, FW; Jensvold, B, 2003) |
| "We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner." | 4.83 | Scleritis complicating zoledronic acid infusion. ( Badros, A; Benderson, D; Karakunnel, J; Kathuria, S, 2006) |
| "To evaluate reported cases of scleritis and other ocular side effects associated with pamidronate disodium, with emphasis on previously unreported cases of scleritis." | 3.72 | Scleritis and other ocular side effects associated with pamidronate disodium. ( Fraunfelder, FT; Fraunfelder, FW; Jensvold, B, 2003) |
| " Pamidronate, an inhibitor of bone resorption used primarily in the management of tumor-induced hypercalcemia and Paget's disease, is reported to cause conjunctivitis, anterior uveitis, and infrequently episcleritis and scleritis." | 3.72 | Posterior uveitis: an under-recognized adverse effect of pamidronate: 2 case reports. ( Claes, C; Haverbeke, G; Pertile, G; Zeyen, T, 2003) |
| "Uveitis and scleritis are the most serious ocular side effects of bisphosphonate therapy." | 1.35 | Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort. ( French, DD; Margo, CE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| French, DD | 1 |
| Margo, CE | 1 |
| Fraunfelder, FW | 2 |
| Winthrop, K | 1 |
| Suhler, E | 1 |
| Choi, D | 1 |
| Fraunfelder, FT | 3 |
| Jensvold, B | 1 |
| Haverbeke, G | 1 |
| Pertile, G | 1 |
| Claes, C | 1 |
| Zeyen, T | 1 |
| Benderson, D | 1 |
| Karakunnel, J | 1 |
| Kathuria, S | 1 |
| Badros, A | 1 |
| Macarol, V | 1 |
1 review available for pamidronate and Scleritis
| Article | Year |
|---|---|
Scleritis complicating zoledronic acid infusion.
Topics: Aged; Anti-Inflammatory Agents; Bone Density Conservation Agents; Diphosphonates; Humans; Imidazoles | 2006 |
5 other studies available for pamidronate and Scleritis
| Article | Year |
|---|---|
Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Databa | 2008 |
Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort.
Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Databases, Factual; Diphosphona | 2009 |
Scleritis and other ocular side effects associated with pamidronate disodium.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Conjunctivitis; Diphosphonates; Female; Humans; Male | 2003 |
Posterior uveitis: an under-recognized adverse effect of pamidronate: 2 case reports.
Topics: Bone Neoplasms; Bone Resorption; Carcinoma; Conjunctivitis; Diphosphonates; Fatal Outcome; Humans; M | 2003 |
Pamidronate disodium and possible ocular adverse drug reactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conjunctivitis; Diphosphonates; Drug Hypersensitivity; H | 1994 |